Results 191 to 200 of about 5,534,791 (400)

The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review

Advanced Science, EarlyView.
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong, Jin Jiang, Muhammad Hussain, Haoxuan Zhang, Ling Chen, Rongfa Guan   +5 more
wiley   +1 more source

Identification of short side chain bile acids in urine of patients with cerebrotendinous xanthomatosis

Journal of Lipid Research, 1990
Urine from patients with cerebrotendinous xanthomatosis (CTX) was found to contain a number of minor bile acids along with three major bile acids, 7-epicholic acid, norcholic acid, and cholic acid.
T Kuramoto, Y Furukawa, T Nishina, T Sugimoto, R Mahara, M Tohma, K Kihira, T Hoshita   +7 more
doaj  

Hydrogel‐Transformable Probiotic Powder for Targeted Eradication of Helicobacter pylori with Enhanced Gastric Mucosal Repair and Microbiota Preservation

Advanced Science, EarlyView.
A multifunctional, edible, and hydrogel‐transformable probiotic powder is developed based on the “bacteria‐mediated bacterial eradication” strategy. By leveraging the targeted binding capability of L. reuteri to H. pylori, this approach achieves an integrated therapeutic effect, including bactericidality, anti‐inflammation, gastric mucosal repair, and ...
Yongkang Lai, Hanchun Shen, Shige Wang, Yongliang Ouyang, Xinyuan Zhang, Bin Hu, Xiaoyi Zhang, Guisheng Li, Lizhi Xu, Jiulong Zhao   +9 more
wiley   +1 more source

Cholecystectomy prevents expansion of the bile acid pool and inhibition of cholesterol 7α-hydroxylase in rabbits fed cholesterol

Journal of Lipid Research, 2001
To study the effect of cholecystectomy on the regulation of classic and alternative bile acid syntheses, gallbladder-intact (n = 20) and cholecystectomized (n = 20) New Zealand White rabbits were fed either chow or chow with 2% cholesterol (3 g/day ...
Guorong Xu, Gerald Salen, Benjamin L. Shneider, M. Ananthanarayanan, Sarah Shefer, Lin Ma, Ashok Batta, Lien B. Nguyen, Josephine J. Lingutla, G. Stephen Tint, Mark Pcolinsky, Frederick J. Suchy   +11 more
doaj  

On the Metabolism of Bile Acids in the Mouse. Bile Acids and Steroids. 87. [PDF]

, 1959
Henry Danielsson, Taro Kazuno, H. Fex, B. Högberg, P. Kneip, H. Palmstierna   +5 more
openalex   +1 more source

Autocrine GDF10 Inhibits Hepatic Stellate Cell Activation via BMPR2/ALK3 Receptor to Prevent Liver Fibrosis

Advanced Science, EarlyView.
Liver fibrosis is a growing global health burden with no specific treatment. HSC activation is the predominant driver of liver fibrogenesis and the current focus in antifibrotic drug discovery. This study identifies autocrine GDF10 activates BMPR2/ALK3‐SMAD1/5/8‐SMAD7 pathway to counteract the TGF‐β‐SMAD2/3 pathway in HSCs, thereby inhibiting HSC ...
Yinliang Zhang, Xiaochen Gai, Yuhui Li, Zuoyu Chen, Xi Zhang, Wei Qiao, Ping Qiu, Chunyuan Du, Sufang Sheng, Jingran Hao, Yujie Zhang, Heng Fan, Xiaorong Li, Ming Liu, Jun Zhang, Zhe Pan, Yongsheng Chang   +16 more
wiley   +1 more source

Estimation of bile acid pool sizes from their spillover into systemic blood.

Journal of Lipid Research, 1985
We have examined the possibility of assessing primary bile acid pool sizes from the spillover of the bile acids into systemic blood after intestinal exposure to the total endogenous bile acid pool; the studies were carried out in 16 healthy subjects ...
S D van der Werf, G P van Berge Henegouwen, W van den Broek   +2 more
doaj  

Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis

Nature reviews: Gastroenterology & hepatology, 2018
Wei Jia, G. Xie, Weiping Jia
semanticscholar   +1 more source

Generation of a High‐Precision Whole Liver Panorama and Cross‐Scale 3D Pathological Analysis for Hepatic Fibrosis

Advanced Science, EarlyView.
Using the MOSTtechnology and whole‐liver Nissl staining method, a multi‐structural 3D pathological panorama of liver fibrosis is obtained. The damaged sinusoids, steatotic hepatocytes, and collagen deposition are all concentrated in pericentral areas.
Xiaochuan Zhang, Weicheng Yang, Xiaoliang Li, Yanli Zhao, Zongneng Xie, Shuangqu Li, Yue Zeng, Xiaoxu Hao, Xiaohong Xin, Yu Zhang, Zixuan Feng, Hualiang Jiang, Zhaobing Gao, Xianzhen Yin   +13 more
wiley   +1 more source

Ursodeoxycholic acid, chenodeoxycholic acid, and 7-ketolithocholic acid are primary bile acids of the guinea pig.

Journal of Lipid Research, 1990
Guinea pig gallbladder bile contains chenodeoxycholic acid (62 +/- 5%), ursodeoxycholic acid (8 +/- 5%), and 7-ketolithocholic acid (30 +/- 5%). All three bile acids became labeled to the same specific activity within 30 min after [3H]cholesterol was ...
GS Tint, GR Xu, AK Batta, S Shefer, W Niemann, G Salen   +5 more
doaj