Results 231 to 240 of about 391,701 (312)

AHR Deficiency Exacerbates Hepatic Cholesterol Accumulation via Inhibiting Bile Acid Synthesis in MAFLD Rats. [PDF]

Int J Mol Sci
Xu J, Liu P, Wu Y, He H, Hu D, Sun J, Chen J, Tian Y, Gong L.   +8 more
europepmc   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Structural mapping of NTCP distinguishes its dual functionality as a hepatitis B virus receptor and bile acid transporter. [PDF]

PLoS Pathog
Matsuzawa K, Ekimoto T, Kobayashi C, Shionoya K, Mifune J, Morita T, Takeuchi JS, Park SY, Ikeguchi M, Sureau C, Kawaguchi A, Watashi K.   +11 more
europepmc   +1 more source

Biliary secretion of alkalyne phosphatase (AP) in man: dependency on the bile acid (BA) secretion and detergency of BA pool

, 1983
Maurizio Ponz De Leon, Marco Bertolotti
openalex   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Microbiota-Mediated Bile Acid Metabolism as a Mechanistic Framework for Precision Nutrition in Gastrointestinal and Metabolic Diseases. [PDF]

Cells
Kang S, Jeong DY, Seo J, Daily JW, Park S.   +4 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Noscapine-bile acid hybrids as novel anticancer agents. [PDF]

RSC Med Chem
Babanezhad Harikandei K, Salehi P, Hasanpour Z, Bararjanian M, Kim W, Asghari SM, Mardinoglu A.   +6 more
europepmc   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

A Screening Assay for Bile Acid-Transforming Microorganisms Using Engineered Bacterial Biosensors. [PDF]

Biosensors (Basel)
Dallera D, Pastorelli D, Bellato M, Frusteri Chiacchiera A, Usai F, Cusella De Angelis MG, Brun P, Magni P, Pasotti L.   +8 more
europepmc   +1 more source