Results 221 to 230 of about 371,534 (304)

Increased Risk of Intrahepatic Cholestasis of Pregnancy in SLE Women Exposed to Azathioprine

Arthritis &Rheumatology, Accepted Article.
Objectives To evaluate the risk of intrahepatic cholestasis of pregnancy (ICP) in azathioprine (AZA)‐exposed versus unexposed SLE pregnancies within the multi‐centre prospective Lupus in prEGnAnCY (LEGACY) cohort. Methods LEGACY is conducted at Systemic Lupus International Collaborating Centres in Canada, South Korea, Peru, and Mexico.
Reem Farhat, Maria del Carmen Zamora‐Medina, Sang‐Cheol Bae, Megan R.W. Barber, Ann E. Clarke, Paul R. Fortin, Zahi Touma, Carl A. Laskin, Isabelle Malhamé, Giada Sebastiani, Christine Peschken, Manuel F. Ugarte‐Gil, Alexandra Legge, Sasha Bernatsky, Évelyne Vinet   +14 more
wiley   +1 more source

MS/MS Mass Spectrometry Filtering Tree for Bile Acid Regio- and Stereoisomer Annotation. [PDF]

Anal Chem
Mohanty I, Xing S, Castillo V, Agongo J, Patan A, El Abiead Y, Mannochio-Russo H, Gonçalves Nunes WD, Zemlin J, Mizrahi I, Siegel D, Wang M, Hagey LR, Dorrestein PC.   +13 more
europepmc   +1 more source

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

A microbiota-dependent bile acid reprograms alveolar macrophages to control lung inflammation. [PDF]

Signal Transduct Target Ther
Wolska M, Rodríguez-Viso P, Świątkowska A, Bulanda E, Wypych TP.   +4 more
europepmc   +1 more source

Bile Acids

Journal of Biological Chemistry, 1959
Robert L. Ratliff, John T. Matschiner, E.A. Doisy, S.L. Hsia, Sidney A. Thayer, William H. Elliott, Edward A. Doisy   +6 more
openaire   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Taurine Facilitates the Formation of Hepatocellular Carcinoma via the Bile Acid Pathway. [PDF]

Metabolites
Huang Q, Mao X, Zhang T, Zhang Y, Lan Z, Fang R, Xiong J, Li J, Sun Y.   +8 more
europepmc   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Dietary Fiber Regulation of Gut Microbiota and Bile Acid Metabolism in Animals: Implications for Animal Nutrition. [PDF]

Vet Sci
Lai J, Zentek J, Grześkowiak ŁM.
europepmc   +1 more source

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source