Results 251 to 260 of about 354,033 (333)

Studies on Bile Salts of Toad (Bufo vulgaris japonicus). XI. Formation of Norcholic Acid from Δ²³-3(α), 7(α), 12(α)-Trihydroxycoprostenic Acid C₂₇H₄₄O₅ and Stem Acid C₂₇H₄₆O₂

, 1953
Shõhei Hayakawa
openalex   +2 more sources

Microbiome‐Informed Dosing: Exploring Gut Microbial Communities Impact on Mycophenolate Enterohepatic Circulation and Therapeutic Target Achievement

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacomicrobiomics is an emerging field due to important microbiome effects on pharmacokinetics and clinical outcomes. However, the application of this knowledge remains limited. Mycophenolic acid (MPA) is the primary active metabolite of the immunosuppressant, mycophenolate mofetil (MMF).
Abdelrahman Saqr, Shen Cheng, Mahmoud Al‐Kofahi, Christopher Staley, Pamala A. Jacobson   +4 more
wiley   +1 more source

The role of bile acid metabolism-related genes in prognosis assessment of hepatocellular carcinoma and identification of NPC1 as a biomarker. [PDF]

Front Endocrinol (Lausanne)
Xu M, Zhang Y, Tie Y, Luo Y, Wang Y, Zhang Z.   +5 more
europepmc   +1 more source

The Synthesis of Stero-bile Acid. VI. The Synthesis of Trihydroxycoprostane

, 1954
Taro Kazuno, A. Mori
openalex   +2 more sources

Advancing Predictions of Oral Drug Absorption, CYP3A4 Induction, and Transporter‐Mediated Interactions Using a Human Primary Intestinal 3D Model (EpiIntestinal™)

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate prediction of oral drug absorption in humans is essential for early drug development; however, physiologically relevant human models are lacking. This study aims to comprehensively assess the EpiIntestinal™, a human primary intestinal 3D model, for its ability to predict oral absorption (Fa), intestinal availability (Fg), CYP3A4 induction, and
Paresh P. Chothe, Andrea Whitcher‐Johnstone, Aniruddha Karve, Diane Ramsden, Niresh Hariparsad   +4 more
wiley   +1 more source

Calorie restriction plugs lithocholic bile acid into the lysosomal AMPK pathway. [PDF]

Life Metab
Viollet B.
europepmc   +1 more source

Infant Death due to Cannabis Ingestion

Drug Testing and Analysis, EarlyView.
ABSTRACT A child died in the emergency room of a local hospital a few hours after ingesting a substance the color of cork and the consistency of earth. At home, a modest amount of resinous substance was found. At the hospital, the child exhibited alterations in walking, balance, and consciousness.
Donata Favretto, Antonello Cirnelli, Roberto Pertile, Raffaella Stimamiglio, Clara Cestonaro, Oriana Cuman, Anna Pagliaro, Fabio Mattiazzi, Cristina Basso, Maddalena Galeazzi   +9 more
wiley   +1 more source

Aerobic Capacity and Exercise Mediate Protection Against Hepatic Steatosis via Enhanced Bile Acid Metabolism. [PDF]

Function (Oxf)
Kugler BA, Maurer A, Fu X, Franczak E, Ernst N, Schwartze K, Allen J, Li T, Crawford PA, Koch LG, Britton SL, Shankar K, Burgess SC, Thyfault JP.   +13 more
europepmc   +1 more source

The Synthesis of Stero-bile Acid. IV. The Partial Synthesis of Norsterocholic Acid

, 1953
Tatsumi BABA
openalex   +2 more sources

A Comprehensive Review on Capillary Electrophoresis–Mass Spectrometry in Advancing Biomolecular Research

ELECTROPHORESIS, EarlyView.
ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont, María Vergara‐Barberán, Enrique Javier Carrasco‐Correa   +2 more
wiley   +1 more source