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Bile acid sulfates in serum bile acids determination
Steroids, 1979Some bile acid sulfates were synthesized and characterized. The configuration of sulfate groups at C-3, C-7 and C-12 positions was confirmed by Nuclear Magnetic Resonance analysis. These sulfates were utilized in a study of their chemical behaviour in different analytical procedures currently used for serum bile acids determination. Procedures for bile
J F, Pageaux +3 more
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Digestive Diseases, 1998
Bile acids normally undergo enterohepatic circulation. When this circulation is interrupted, bile acids enter the colon in increased concentrations. Here, they produce Cl<sup>–</sup> secretion by a calcium- and cyclic AMP-dependent mechanism, resulting in diarrhea.
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Bile acids normally undergo enterohepatic circulation. When this circulation is interrupted, bile acids enter the colon in increased concentrations. Here, they produce Cl<sup>–</sup> secretion by a calcium- and cyclic AMP-dependent mechanism, resulting in diarrhea.
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Species differences in bile acids II. Bile acid metabolism
Journal of Applied Toxicology, 2018AbstractOne of the mechanisms of drug‐induced liver injury (DILI) involves alterations in bile acid (BA) homeostasis and elimination, which encompass several metabolic pathways including hydroxylation, amidation, sulfation, glucuronidation and glutathione conjugation.
Rhishikesh Thakare +4 more
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Bile acids. LIV—Mass spectra of conjugated bile acids
Biological Mass Spectrometry, 1978The electron impact mass spectra of conjugated bile acids, their 5alpha-analogs and methyl esters of glyco conjugates were determined by direct insertion into the ion source and their fragmentation patterns were found to be basically similar to those of methyl esters of the free bile acids. The conjugates are additionally characterized by a significant
R, Shaw, W H, Elliott
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Journal of Chromatography B: Biomedical Sciences and Applications, 1995
A review of the methods available for the separation of bile acids is presented, highlighting the most recent developments. The major chromatographic techniques (TLC, GC, HPLC) and combined detection systems for the determination of bile acids are critically evaluated and their advantages and disadvantages discussed.
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A review of the methods available for the separation of bile acids is presented, highlighting the most recent developments. The major chromatographic techniques (TLC, GC, HPLC) and combined detection systems for the determination of bile acids are critically evaluated and their advantages and disadvantages discussed.
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Bile acids and the gut microbiota: metabolic interactions and impacts on disease
Nature Reviews Microbiology, 2022Stephanie Collins +2 more
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