Results 151 to 160 of about 234,802 (359)
Surface Balance Studies of Bile Acid Monolayers. II. Monolayers of Litocholic and Glycolitocholic Acids. [PDF]
Per Ekwall+4 more
openalex +1 more source
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang+10 more
wiley +1 more source
Effects of cholestatic drugs towards hepatic canalicular and sinusoidal secretion of bile acids were investigated using a biphasic functional assay in human hepatoma HepaRG cells. After an initial loading phase with taurocholate, cells were re‐incubated in taurocholate‐free medium (efflux phase), with or without calcium (for modulating the opening of ...
Marc Le Vée+5 more
wiley +1 more source
During the last 80 years there have been extraordinary advances in our knowledge of the chemistry and biology of bile acids. We present here a brief history of the major achievements as we perceive them.
Alan F. Hofmann, Lee R. Hagey
doaj
LC/ESI-MS analysis of underivatized amino acids and mass spectrum [PDF]
We report the method of LC/ESI-MS analysis of underivatized amino acids with corresponding mass spectrum and fragmentation patterns. Diagnostic product ions determined by mass spectrometry can support the qualitative identification and quantitative estimation of individual amino acids. Therefore, the optimization of chromatographic separation using the
arxiv
The Role of Bifidobacterium SPP. on Cholestrol Assimilation in the in Vitro and in Vivo Studies [PDF]
The purpose of this study was to investigate the cholesterol removal by some bifidobacterium spp. at in vitro and in vivo conditions with the emphasis of their bile salt deconjugation ability.
Sabet, Maryam Rezaei
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Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation and extracellular matrix stiffening. An in vitro NAFLD model is developed using engineered hydrogels (G′ ≈ 1–6 kPa) and iPSC‐derived hepatic organoids. It is demonstrated that higher stiffness can increase lipid droplet accumulation, fibrosis, and metabolic dysregulation ...
Yueming Liu+11 more
wiley +1 more source
Proton magnetic resonance assay of total and taurine-conjugated bile acids in bile
Biliary bile acids, coexisting with phospholipid and cholesterol, are partly conjugated with taurine. In the present report we show that total and taurine-conjugated bile acids in bile can be simultaneously and quantitatively measured by high-resolution ...
Hiroki Ishikawa+8 more
doaj
Correlations of Amino Acids with Secondary Structure Types: Connection with Amino Acid Structure [PDF]
The correlations of primary and secondary structures were analyzed using proteins with known structure from Protein Data Bank. The correlation values of amino acid type and the eight secondary structure types at distant position were calculated for distances between -25 and 25.
arxiv
Downregulation of intestinal Farnesoid X Receptor in Erythropoietic protoporphyria [PDF]
Erythropoietic protoporphyria (EPP) is characterized by accumulation of protoporphyrin IX (PPIX) in the body. The liver is the major organ responsible for PPIX excretion through the biliary system. Because PPIX is highly hydrophobic, an excess amount of
Pradhan, Komal
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