Results 181 to 190 of about 234,802 (359)

m6A‐Mediated TMCO3 Promotes Hepatocellular Carcinoma Progression by Facilitating the Membrane Translocation and Activation of AKT

open access: yesAdvanced Science, EarlyView.
TMCO3 as a downstream target of ALKBH5 is found, which regulates its expression in an m6A‐dependent manner, and then a new phosphorylation site on TMCO3 is identified and determines the specific mechanism of TMCO3 with AKT. Moreover, the combined treatment of targeting the TMCO3 and inhibition of AKT in mice models with HCC achieves great results ...
Xinxin Li   +8 more
wiley   +1 more source

Epipolythiodioxopiperazine‐Based Natural Products: Building Blocks, Biosynthesis and Biological Activities

open access: yesChemBioChem, Volume 23, Issue 23, December 5, 2022., 2022
Housing sulfur: Certain fungi produce diketopiperazine compounds with a transannular sulfur bridge. These so‐called epipolythiodioxopiperzines are toxic by non‐specifically interacting with intracellular proteins and contribute to fungal pathogenicity. Producer strains serve as bio‐pesticides but also question safety of food fermentation.
Eva M. Huber
wiley   +1 more source

Biliary secretion and excretion in health and disease: Current concepts

open access: yesAnnals of Hepatology, 2007
Biliary secretion in health and disease is reviewed. The powerful techniques of molecular biology have enabled cloning of the transporters involved in biliary secretion and the enterohepatic circulation of bile acids.
Alan F Hofmann
doaj  

THE ESTIMATION OF BILE ACIDS IN URINE

open access: hybrid, 1923
Carl L.A. Schmidt, John Merrill
openalex   +1 more source

Occurrence of sulfated 5α-cholanoates in rat bile1

open access: yesJournal of Lipid Research, 1978
Bile acids in bile from male and female rats with cannulated bile ducts have been analyzed by repetitive scanning gas–liquid chromatography–mass spectrometry after initial fractionation of conjugate classes on diethylaminohydroxypropyl Sephadex LH-20 ...
H Eriksson, W Taylor, J Sjövall
doaj  

Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis [PDF]

open access: yes
The leukemia inhibitory factor (LIF) is member of interleukin (IL)-6 family of cytokines involved immune regulation, morphogenesis and oncogenesis. In cancer tissues, LIF binds a heterodimeric receptor (LIFR), formed by a LIFRβ subunit and glycoprotein ...
Bellini, Rachele   +21 more
core   +1 more source

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

open access: yesCell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner   +8 more
wiley   +1 more source

Stereochemical Course of the Conversion of Cholesterol to Bile Acid. [PDF]

open access: bronze, 1959
S. Bergström   +3 more
openalex   +1 more source

Nationwide medical database study for postoperative nutritional management in patients undergoing gastroenterological cancer surgery

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The study aim was to clarify how nutrition was managed in patients based on surgical site during the first 7 d after gastrointestinal cancer surgery. As results, oral intake after gastrointestinal cancer surgery started earliest in patients having liver surgery and latest in patients having esophageal surgery.
Yoshikuni Kawaguchi   +3 more
wiley   +1 more source

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