Results 201 to 210 of about 139,449 (267)

The Synthesis of Stero-bile Acids. XV

, 1955
K. Fuziwara
openalex   +2 more sources

Beyond mammals: the evolution of chewing and other forms of oropharyngeal food processing in vertebrates

Biological Reviews, EarlyView.
ABSTRACT Oropharyngeal food processing exhibits a remarkable diversity among vertebrates, reflecting the evolution of specialised ‘processing centres’ associated with the mandibular, hyoid, and branchial arches. Although studies have detailed various food‐processing strategies and mechanisms across vertebrates, a coherent and comprehensive terminology ...
Daniel Schwarz, Maja Mielke, Stephan Handschuh, Anthony Herrel, Patrick Lemell, Léa Da Cunha, Nicolai Konow   +6 more
wiley   +1 more source

Central effects of bile acids on feed intake and mRNA expression of appetite-related neuropeptides in layer-type chicks. [PDF]

Poult Sci
Ghashghaei E, Mijiyawa A, Wang M, Zendehdel M, Lin H.   +4 more
europepmc   +1 more source

MECHANISMS OF BILE ACIDS ACTION ON PANCREATIC DUCTAL CELLS

, 2019
Л. А. Можейко
openalex   +2 more sources

Quantitative Systems Toxicology Modeling with DILIsym to Support Phase 3 Dose Selection for Fezolinetant

Clinical Pharmacology &Therapeutics, EarlyView.
Fezolinetant is a first‐in‐class, selective, non‐hormonal, neurokinin 3 receptor antagonist that is approved for the treatment of moderate to severe vasomotor symptoms due to menopause. In a phase 2b clinical study (n = 352), nine study participants experienced elevations in serum transaminases exceeding three times the upper limit of normal.
Jace C. Nielsen, Jeffrey L. Woodhead, Brett A. Howell, Lisl K. M. Shoda, Dolly A. Parasrampuria, Jiayin Huang, Megumi Iwai, Faith D. Ottery, Xuegong Wang, Marci English, Kentaro Miyazaki, Paul B. Watkins   +11 more
wiley   +1 more source

Biological Actions of Bile Acids via Cell Surface Receptors. [PDF]

Int J Mol Sci
Kiriyama Y, Tokumaru H, Sadamoto H, Nochi H.   +3 more
europepmc   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source

Bile acids and their receptors in hepatic immunity. [PDF]

Liver Res
Fiorucci S, Marchianò S, Distrutti E, Biagioli M.   +3 more
europepmc   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Maternal bile acids supplementation improves follicular development and offspring gut barrier by modulating Hedgehog-GnRH aixs and antioxidant pathways. [PDF]

Poult Sci
Xing R, Lei L, Fan Z, Wang L, Luo L, Huang Y, Zhang H, Feng Z, Chen W, Si X.   +9 more
europepmc   +1 more source