Results 221 to 230 of about 238,773 (337)

Artificial intelligence modelling of tyrosine kinase inhibitors at risk of malabsorption and bioavailability‐enhancing strategies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens   +8 more
wiley   +1 more source

Infrared-spectroscopic Studies on Bile Acids. [PDF]

open access: bronze, 1958
Ingrid Fischmeister   +5 more
openalex   +1 more source

Intergenerational Enlargement of Human Organs as a Driver of Increased Cancer Risk?

open access: yesBioEssays, Volume 47, Issue 8, August 2025.
Identifying the environmental factors and associated mechanisms driving increased cancer incidence in younger generations is a matter of great urgency. Here, we propose and discuss a new potential mechanism: larger organ sizes in younger individuals resulting from intergenerational differences in lifestyle, diet, and environmental exposures.
Costas Koufaris, Vicky Nicolaidou
wiley   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Carcinogenic and anticancer activities of microbiota-derived secondary bile acids. [PDF]

open access: yesFront Oncol
Kouhzad M   +7 more
europepmc   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

open access: yesCancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong   +10 more
wiley   +1 more source

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