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Bile acids and their receptors

Molecular Aspects of Medicine, 2017
Primary bile acids are synthetized from cholesterol within the liver and then transformed by the bacteria in the intestine to secondary bile acids. In addition to their involvement in digestion and fat solubilization, bile acids also act as signaling molecules. Several receptors are sensors of bile acids.
Martinot, Emmanuelle   +6 more
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Bile acid sulfates in serum bile acids determination

Steroids, 1979
Some bile acid sulfates were synthesized and characterized. The configuration of sulfate groups at C-3, C-7 and C-12 positions was confirmed by Nuclear Magnetic Resonance analysis. These sulfates were utilized in a study of their chemical behaviour in different analytical procedures currently used for serum bile acids determination. Procedures for bile
Bernard Duperray   +3 more
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Bile acids LVII. Bile acids and colorectal cancer

Lipids, 1978
AbstractSignificant correlations have been reported by epidemiologists between the mortality from colorectal cancer in various populations and the consumption of meat or lipids by these populations. These have directed considerable attention to possible relationships between diet and the occurrence of this neoplasm.
William H. Elliott, J. Wendell Davis
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BILE ACID TRANSPORT

Gastroenterology Clinics of North America, 1999
Bile acids undergo a unique enterohepatic circulation, which allows them to be efficiently reused with minimal loss. With the cloning of key bile acid transporter genes in the liver and intestine, clinicians now have a detailed understanding of how the different components in the enterohepatic circulation operate.
Ron Bahar, Andrew Stolz
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Microbial transformation of bile acids. A unified scheme for bile acid degradation, and hydroxylation of bile acids

Zeitschrift für allgemeine Mikrobiologie, 1982
AbstractThrough the isolation and identification of a wide variety of degradation products formed from bile acids by microorganisms, a unified scheme for the complete degradation of bile acids to carbon dioxide and water has been proposed and discussed.
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Bile Acid Synthesis

Annual Review of Physiology, 1983
Cholesterol is the obligatory precursor of bile acids, and the liver is the sole source and site of bile acid formation (1). In the transformation of choles­ terol to bile acids, the cyclopentanophenanthrene nucleus is first believed to undergo modifications followed by oxidation and cleavage of the choles­ terol side-chain.
Sarah Shefer, Gerald Salen
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Bile-Acid Malabsorption

JAMA: The Journal of the American Medical Association, 1979
To the Editor.— We read the stimulating report by Hutcheon et al (241:823, 1979) concerning observation of bile-acid malabsorption in three postcholecystectomy patients and the response to cholestyramine therapy. Our group has reported a similar experience 1-3 in three postcholecystectomy patients in whom bile-acid malabsorption was shown by studies ...
H. Fromm, R. P. Sarva
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Bile acid separation

Journal of Chromatography B: Biomedical Sciences and Applications, 1995
A review of the methods available for the separation of bile acids is presented, highlighting the most recent developments. The major chromatographic techniques (TLC, GC, HPLC) and combined detection systems for the determination of bile acids are critically evaluated and their advantages and disadvantages discussed.
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