Results 81 to 90 of about 234,802 (359)

Critical roles of bile acids in regulating intestinal mucosal immune responses

Therapeutic Advances in Gastroenterology, 2021
Bile acids are a class of cholesterol derivatives that have been known for a long time for their critical roles in facilitating the digestion and absorption of lipid from the daily diet.
Ruicong Sun, Chunjin Xu, Baisui Feng, Xiang Gao, Zhanju Liu   +4 more
doaj   +1 more source

The role of fibroblast growth factor 19 in human liver [PDF]

, 2020
Bile acids are synthesized in the liver and are essential for intestinal absorption of lipids. Bile acid homeostasis is crucial and if not maintained, bile acids can accumulate to toxic levels and cause severe damage to the liver. Bile acid homeostasis
Johansson, Heléne
core   +1 more source

Polymer Nanogels with Albumin Reporting Interface Created Using RAFT Precipitation Polymerization for Disease Diagnosis and Food Testing

Advanced Materials Interfaces, EarlyView.
Herein, polymer nanogels with a reporting interface for albumin are synthesized through reversible addition–fragmentation chain transfer (RAFT) precipitation polymerization of di(ethylene glycol) methyl ether methacrylate and N,N’‐methylenebis(acrylamide) using a poly(2‐methacryloyloxyethyl phosphorylcholine) macro‐RAFT agent, followed by dansyl ...
Yukiya Kitayama, Erika Yoshimatsu, Atsushi Harada   +2 more
wiley   +1 more source

Fasting levels of monoketonic bile acids in human peripheral and portal circulation

Journal of Lipid Research, 1982
It has been suggested that large amounts of ketonic bile acids may be present in portal venous blood. We have therefore determined the approximate concentration of 3-oxo-, 7-oxo-, and 12-oxo-bile acids (monoketonic bile acids) in human peripheral and ...
I Björkhem, B Angelin, K Einarsson, S Ewerth   +3 more
doaj  

Electrophotographic Powder Application for Surface Functionalization of Polymer Parts with Thin Silver‐Nanoadditivated Bactericidal Layers

Advanced Materials Technologies, EarlyView.
Polyamide 12 powder nanoadditivated with laser‐synthesized silver nanoparticles is deposited and sintered on polymer parts via EPA‐PBF‐LB/P. The thin surface coating (140 µm) inhibits E. coli and S. aureus bacteria growth and significantly increases the UV light absorption, whereas the mechanical and thermal properties remain unchanged due to minimal ...
Jan Lino Kricke, Niklas Ebert, Ane Sorarrain, Stephan Roth, Dagmar Fischer, Michael Schmidt, Bilal Gökce, José María Marimón, Sebastian‐Paul Kopp, Carlos Doñate‐Buendía   +9 more
wiley   +1 more source

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

Advanced Science, EarlyView.
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou, Li Li, Peidi Ren, Ting‐Ting Zhou, Fan He, Jialing Chen, Huimin Cai, Xiumin Han, Yao‐Dong Wu, Jiandong Li, Xiu‐Rong Li, Qiming Tan, Wenhui Li, Qi Chen, Nian‐Zhang Zhang, Xiuju He, Wei‐Gang Chen, Yanping Zhao, Jiwen Sun, Qian Zhang, Yan‐Tao Wu, Yingan Liang, Jie You, Guohai Hu, Xue‐Qi Tian, Sha Liao, Bao‐Quan Fu, Ao Chen, Xue‐Peng Cai, Huanming Yang, Jian Wang, Xin Jin, Xun Xu, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan   +35 more
wiley   +1 more source

Hepatic bile acid uptake: effect of conjugation, hydroxyl and keto groups, and albumin binding

Journal of Lipid Research, 1982
Hepatic extraction of trihydroxy (free, glyco- and tauro-conjugated) dihydroxy, and monohydroxy bile acids has been evaluated in single pass liver perfusion experiments in rats.
R Aldini, A Roda, A M Labate, G Cappelleri, E Roda, L Barbara   +5 more
doaj  

Dysregulation of Bile Acids in Patients with NAFLD [PDF]

, 2018
Bile acids are synthesized in the liver and tightly regulated through the enterohepatic circulation. Recent studies reveal that bile acids serve as hormone-like signaling molecules to activate nuclear receptors, notably farnesoid X receptor (FXR ...
Deng, Ruitang, Zhang, Xinmu
core   +2 more sources

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Advanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li   +16 more
wiley   +1 more source

Characterization of the adsorption of conjugated and unconjugated bile acids to insoluble, amorphous calcium phosphate.

Journal of Lipid Research, 1994
Recently we showed that supplemental dietary calcium stimulates the intestinal formation of insoluble calcium phosphate and decreases the ratio of dihydroxy to trihydroxy bile acids in human duodenal bile. Because previous in vitro studies indicated that
M J Govers, D S Termont, G A Van Aken, R Van der Meer   +3 more
doaj