Results 281 to 290 of about 29,638 (318)

Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat

Digestive Diseases and Sciences, 1994
Taurohyodeoxycholic acid is a natural 6 alpha-hydroxylated bile acid with an apparent hydrophilicity intermediate between those of tauroursodeoxycholic and taurocholic acids. We investigated in the rat the hepatobiliary metabolism, choleretic properties, and biliary maximum secretory rate (SRmax) of taurohyodeoxycholic in comparison with these two bile
Mario Angelico, Leonardo Baiocchi, Alessandra Nistri, FRANCHITTO, Antonio, P. Della Guardia, GAUDIO, EUGENIO   +5 more
openaire   +5 more sources

Mixed Micelles of Sodium Salts of Bile Acids and Tween 40: Effect of the Steroid Skeleton on the Coefficient of Interaction in Mixed Micelles

, 2012
Salts of bile acids are steroid amphiphilic compounds which form micelles consisting of 2–12 monomer units. In nature, the formation of mixed micelles with phospholipids (gall bladder) increases the capacity of bile salts to solubilize cholesterol.
Mihalj Poša, D. Ćirin
semanticscholar   +1 more source

A Comparative Study of the Choleretic Effect of Bile Salts and Oleic Acid and Bile Salts

Annals of Internal Medicine, 1933
Excerpt For the past year we have employed a mixture of oleic acid and bile salts for the treatment of patients suffering from various forms of gall-bladder disease.
Reuben Finkelstein, Emanuel W. Lipschutz
openaire   +2 more sources

Spread monomolecular films of monohydroxy bile acids and their salts: influence of hydroxyl position, bulk pH, and association with phosphatidylcholine.

Biochemistry, 2000
Undissociated dihydroxy bile acids, alone or with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), lie with their long axes parallel to aqueous-lipid interfaces [Fahey, D. A., Carey, M. C., and Donovan, J. M. (1995) Biochemistry 34, 10886-10897].
M. R. Leonard, M. Bogle, M. Carey, J. Donovan   +3 more
semanticscholar   +1 more source

Polycationic salts as bile acid sequestering agents

Progress in Polymer Science, 1999
Abstract A review of bile acid chemistry is included in this paper. The structures, chemistry, physiology and metabolism of the bile acids and their effects on the human body are discussed. Additionally, the precursor of bile acids are examined at length as are current treatments for diseases arising from high levels of cholesterol or the ...
P. Zarras, Otto Vogl
openaire   +2 more sources

Sodium salts of bile acids in aqueous micellar solutions

2007
Aqueous micellar solutions of deoxycholate (DC), glycodeoxycholate (GDC), and taurodeoxycholate (TDC) were studied to find the predominant species and their formation constants.
BOTTARI, Emilio Giovanni, FESTA, Maria Rosa   +1 more
openaire   +4 more sources

Effects of acid and bile salts on the rabbit esophageal mucosa

Digestive Diseases and Sciences, 1981
We used the rabbit esophagus as a model to study clinically significant variables which may be important in the pathophysiology of reflux esophagitis in man.* Increased permeability to hydrogen ion, as indicated by a net acid flux (NAF) out of the lumen, was our index of injury.
John W. Harmon, John W. Harmon, John W. Harmon, Lawrence F. Johnson, Lawrence F. Johnson, Lawrence F. Johnson, Corrine L. Maydonovitch, Corrine L. Maydonovitch, Corrine L. Maydonovitch   +8 more
openaire   +3 more sources

Molecular interactions between lecithin and bile salts/acids in oils and their effects on reverse micellization.

Langmuir, 2013
It has been known that the addition of bile salts to lecithin organosols induces the formation of reverse wormlike micelles and that the worms are similar to long polymer chains that entangle each other to form viscoelastic solutions.
Ching-Wei Njauw, Chih-Yang Cheng, V. Ivanov, A. Khokhlov, S. Tung   +4 more
semanticscholar   +1 more source

Bile and pancreatic secretion in chickens: the effects of bile salts, feeding and acid

Comparative Biochemistry and Physiology Part A: Physiology, 1978
Abstract 1. 1. Bile production decreased after bile diversion, but increased when bile was returned to the duodenum, and during i.v. infusion of chenodeoxycholic and of taurocholic acid. In chickens, unlike rabbits, rats and guinea pigs, only a small fraction of bile flow was apparently independent of bile salt secretion. 2. 2.
C. G. Halpin, Ivan W Caple, Trevor Heath
openaire   +2 more sources

Bile salt hydrolase acyltransferase activity expands bile acid diversity

Nature
Bile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-soluble vitamins while shaping the gut microbiome because of their antimicrobial properties1-4. Here we identify the enzyme responsible for a mechanism of BA metabolism by the gut microbiota involving amino acid conjugation to the acyl-site of BAs, thus ...
Douglas V. Guzior, Maxwell Okros, Madison Shivel, Bruin Armwald, Christopher Bridges, Yousi Fu, Christian Martin, Anthony L. Schilmiller, Wendy M. Miller, Kathryn M. Ziegler, Matthew D. Sims, Michael E. Maddens, Stewart F. Graham, Robert P. Hausinger, Robert A. Quinn   +14 more
openaire   +2 more sources