Results 301 to 310 of about 57,138 (354)

Cholesterol, bile acid and bile salt adsorption to bran in vitro

Pharmacological Research Communications, 1981
Summary The in vitro adsorption of cholesterol (C) (0.6–1.1mM), bile acids (BA) and bile salts (BS) (5–10mM) on to bran and Amberlite XAD-2 (0.5 g) was studied. After the mixtures were shaken, three phases were obtained: phase 1 (the supernatant containing no bound lipids) phase 2 (bran and Amberlite were washed with buffer in order to obtain weakly ...
G, Salvioli, R, Salati, M, Pastorello, A, Gibertini   +3 more
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Human OATP1B1 (SLCO1B1) transports sulfated bile acids and bile salts with particular efficiency

Toxicology in Vitro, 2018
Human OATP1B1 is highly expressed at the basolateral membrane of the hepatocyte. It plays an important role in the sodium-independent transport of bile acids and bile salts and contributes to the systemic clearance of many drugs. In this study, the interaction of at least one representative of all major chemical classes of bile acids and bile salts ...
Toth, Beata; Jani, Marton; Beery, Erzsebet; Heslop, Teresa; Bayliss, Mark; Kitteringham, Neil R.; Park, B. Kevin; Weaver, Richard J.; Krajcsi, Peter   +9 more
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Subcellular distribution of bile acids, bile salts, and taurocholate binding sites in rat liver

Biochemistry, 1984
We have quantitated bile acids and their conjugates in rat liver using high-pressure liquid chromatography. Over 95% of the hepatic bile acid pool in rat liver homogenates is present as taurocholate and tauromuricholate. Although over 60% of the bile acid pool is recovered in the supernatant, evidence is presented suggesting that taurocholate ...
F A, Simion, B, Fleischer, S, Fleischer
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A Comparative Study of the Choleretic Effect of Bile Salts and Oleic Acid and Bile Salts

Annals of Internal Medicine, 1933
Excerpt For the past year we have employed a mixture of oleic acid and bile salts for the treatment of patients suffering from various forms of gall-bladder disease.
REUBEN FINKELSTEIN, EMANUEL W. LIPSCHUTZ
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Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat

Digestive Diseases and Sciences, 1994
Taurohyodeoxycholic acid is a natural 6 alpha-hydroxylated bile acid with an apparent hydrophilicity intermediate between those of tauroursodeoxycholic and taurocholic acids. We investigated in the rat the hepatobiliary metabolism, choleretic properties, and biliary maximum secretory rate (SRmax) of taurohyodeoxycholic in comparison with these two bile
Mario Angelico, Leonardo Baiocchi, Alessandra Nistri, FRANCHITTO, Antonio, P. Della Guardia, GAUDIO, EUGENIO   +5 more
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Effects of acid and bile salts on the rabbit esophageal mucosa

Digestive Diseases and Sciences, 1981
We used the rabbit esophagus as a model to study clinically significant variables which may be important in the pathophysiology of reflux esophagitis in man.* Increased permeability to hydrogen ion, as indicated by a net acid flux (NAF) out of the lumen, was our index of injury.
J W, Harmon, L F, Johnson, C L, Maydonovitch   +2 more
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Effects of oleic acid and bile salts on canine villous motility

Life Sciences, 1989
The effects on canine villous motility of mucosal Tyrodes solution containing oleic acid (10 mM) and/or either taurocholic or cholic acid (15 mM) in the presence or absence of IV atropine (1 mg/kg) was used to assess the neural mediation of the effects of luminal nutrients. Villous motility was measured over 12 min periods by in vivo videomicroscopy of
D, Mailman, P, Tso, D N, Granger
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Effect of bile salts and bile acids on human gastric mucosal epithelial cells

Journal of Nanjing Medical University, 2008
Abstract Objective To explore the effect of bile salt and bile acid on cultured eternalized human gastric mucosa epithelium GES-1cells. Methods Cultured eternalized human gastric mucosa epithelium GES-1 cells were treated with media containing 6 different kinds of bile salts and 3 different kinds of bile acids and their mixture with different ...
Yinxue Song, Jun Gong
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Group separation of bile acids and salts by silicic acid column chromatography

Analytical Biochemistry, 1978
Abstract Group separations of unconjugated and conjugated bile acids and salts were performed using mixtures of conventional solvents by chromatography on columns of silicic acid. The results suggest that this method is useful for group separations of mono-, di-, and trihydroxycholan-24-oic acids and their conjugates with good recoveries. This method
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Bile and pancreatic secretion in chickens: the effects of bile salts, feeding and acid

Comparative Biochemistry and Physiology Part A: Physiology, 1978
Abstract 1. 1. Bile production decreased after bile diversion, but increased when bile was returned to the duodenum, and during i.v. infusion of chenodeoxycholic and of taurocholic acid. In chickens, unlike rabbits, rats and guinea pigs, only a small fraction of bile flow was apparently independent of bile salt secretion. 2. 2.
Ivan W Caple, C.G Halpin, Trevor Heath
openaire   +1 more source