Results 71 to 80 of about 57,138 (354)

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Isolation and characterization of Faecalibacterium prausnitzii from calves and piglets. [PDF]

, 2014
The goal of our study was to isolate and characterize Faecalibacterium prausnitzii from fecal samples of healthy calves and piglets, in order to develop a novel probiotic for livestock animals.
Bicalho, Rodrigo C, Dias, Juliana M, Foditsch, Carla, Gaeta, Natália, Pereira, Richard VV, Santos, Thiago MA, Teixeira, Andre GV   +6 more
core   +2 more sources

Acid and bile salts induce DNA damage in human oesophageal cell lines [PDF]

Mutagenesis, 2004
Barrett's oesophagus is an acquired precancerous condition that develops from mucosal injury incurred due to chronic gastro-oesophageal reflux. The aim of this study was to determine if bile and/or acid components of the refluxate can induce DNA damage in vitro.
A J, Jolly, C P, Wild, L J, Hardie
openaire   +2 more sources

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Perinatal bile acid metabolism: analysis of urinary bile acids in pregnant women and newborns

Journal of Lipid Research, 1997
The metabolism of bile acids in 30 pregnant women was evaluated by analyzing the urinary composition of bile acids during late gestation (weeks 30-41) and again in these women and their newborn infants during the first week after delivery.
A Kimura, M Suzuki, T Murai, T Inoue, H Kato, D Hori, Y Nomura, T Yoshimura, T Kurosawa, M Tohma   +9 more
doaj   +1 more source

Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series

Gastroenterology Review, 2021
Pruritus commonly occurs in patients with cholestatic liver diseases. Pruritus that is refractory to pharmacological treatment may be an indication for liver transplantation [1–3]. Pathogenesis of hepatic pruritus is still not fully understood.
Magdalena Antoszewska, Piotr Spychalski, Gerda Elisabeth Villadsen, Niels Kristian Muff Aagaard   +3 more
doaj   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Potential of Lactic Acid Bacteria Isolated From Dangke and Indonesian Beef as Hypocholesterolaemic Agent [PDF]

, 2017
Lactobacillus fermentum strains were successfully isolated from dangke which was a fresh cheese-like product originating from Enrekang, South Sulawesi Province, Indonesia.
Arief, I. I. (I), Burhan, H. (H), Priyambada, S. A. (S), Taufik, E. (E)   +3 more
core  

Effect of Intraduodenal Bile and Na-Taurodeoxycholate on Exocrine Pancreatic Secretion and on Plasma Levels of Secretin, Pancreatic Polypeptide, and Gastrin in Man [PDF]

, 1990
The effect of intraduodenally administered cattle bile (CB) and Na-taurodeoxycholate (TDC) on basal pancreatic secretion and plasma levels of secretin, pancreatic polypeptide (PP), and gastrin were investigated on two separate days in 10 fasting ...
A. Scharl, Aronchick C A, Bjornsson O G, Bondesen S, Burhol P G, Burhol P G, Burhol P G, Carey M C, Davies H A, Dragstedt L R, F. Fiedler, Fahrenkrug J, Flaten O, Florholmen J, Forell M M, Forell M M, Greenberg G R, Gries E, Grossman M I, Hanssen L E, Hartmann W, Hunter W M, I. Hempen, J. Teufel, Jorde R, Konturek S J, Lehnert P, Londong W, Lonovics J, Malagelada J-R., Malagelada J-R., Miyasaka K, Miyazaki K, Moreland H J, Morris B J, Osnes M, Osnes M, Otte M, P. G. Burhol, P. Lehnert, Petersen H, R. L. Riepl, Scatchard G, Schaffalitzky de Muckadell O B, Schwartz T W, Thomas J E, Wormsley K G   +46 more
core   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source