Results 31 to 40 of about 276,357 (160)

Bile salt evolution

open access: yesJournal of Lipid Research, 1967
Viewed against the background of known or supposed biosynthetic pathways for cholic and chenodeoxycholic acids in man and laboratory animals, the chemical nature of bile salts in more primitive animals clearly indicates that evolution from C27, 5α ...
G.A.D. Haslewood
doaj   +1 more source

Role of High total protein in gallbladder bile in the formation of cholesterol gallstones. [PDF]

open access: yes, 1991
While it is generally accepted that cholesterol supersaturation of bile is of key importance in the rapid formation of cholesterol crystals, the role of total biliary protein and pH in the pathogenesis of cholesterol gallstones is less well understood ...
Ritter, Christoph von   +3 more
core   +1 more source

Synthesis of the putative metabolites of plant sterols: (24R)- and (24S)-24-methyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrols and 24-ethyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24 xi-tetrol.

open access: yesJournal of Lipid Research, 1984
This report describes the synthesis of (24R)- and (24S)-24-methyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrols and 24-ethyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24 xi-tetrol starting from cholic acid.
B Dayal   +4 more
doaj   +1 more source

Chemical structures of vertebrate bile alcohols, bile acids, and vitamin D receptor ligands.

open access: yes, 2016
(A) The structure of cholesterol, from which all bile acids and alcohols are derived. The left panel (B-D) depicts representative bile alcohols: (B) 5α-petromyzonol, a C24 bile alcohol that is a unique and minor component of the lamprey bile alcohol pool,
David M. Reif (218469)   +5 more
core   +1 more source

Cholesterol nucleation time in gallbladder bile of patients with solitary or multiple cholesterol gallstones [PDF]

open access: yes, 1992
Patients with multiple cholesterol gallbladder stones have been found to be at a higher risk for the recurrence of gallstones after successful nonsurgical treatment than those with a solitary stone.
Ritter, Christoph von   +4 more
core   +1 more source

Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor

open access: yesJournal of Lipid Research, 2004
Bile acid synthesis from cholesterol is tightly regulated via a feedback mechanism mediated by the farnesoid X receptor (FXR), a nuclear receptor activated by bile acids.
Tomoko Nishimaki-Mogami   +7 more
doaj   +1 more source

Bile acids: analysis in biological fluids and tissues

open access: yesJournal of Lipid Research, 2010
The formation of bile acids/bile alcohols is of major importance for the maintenance of cholesterol homeostasis. Besides their functions in lipid absorption, bile acids/bile alcohols are regulatory molecules for a number of metabolic processes.
William J. Griffiths, Jan Sjövall
doaj   +1 more source

Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27−/− mice and CTX

open access: yesJournal of Lipid Research, 2001
Cerebrotendinous xanthomatosis (CTX) is a rare, recessively inherited lipid storage disease characterized by a markedly reduced production of chenodeoxycholic acid and an increased formation of 25-hydroxylated bile alcohols and cholestanol. Patients with
Akira Honda   +9 more
doaj   +1 more source

Effect of chenodeoxycholic acid on biliary and urinary bile acids and bile alcohols in cerebrotendinous xanthomatosis; monitoring by high performance liquid chromatography.

open access: yesJournal of Lipid Research, 1985
Biliary and urinary bile alcohol and bile acid composition has been determined by high performance liquid chromatography in patients with cerebrotendinous xanthomatosis before and after treatment with chenodeoxycholic acid.
A K Batta, S Shefer, M Batta, G Salen
doaj   +1 more source

Increased urinary excretion of bile alcohol glucuronides in patients with primary biliary cirrhosis.

open access: yesJournal of Lipid Research, 1989
The bile alcohol glucuronides in urine of 12 patients with primary biliary cirrhosis (PBC), 10 patients with chronic active hepatitis (CAH), and 6 healthy volunteers were analyzed by capillary gas-liquid chromatography-mass spectrometry.
S Weydert-Huijghebaert   +3 more
doaj   +1 more source

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