Results 31 to 40 of about 276,357 (160)
Viewed against the background of known or supposed biosynthetic pathways for cholic and chenodeoxycholic acids in man and laboratory animals, the chemical nature of bile salts in more primitive animals clearly indicates that evolution from C27, 5α ...
G.A.D. Haslewood
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Role of High total protein in gallbladder bile in the formation of cholesterol gallstones. [PDF]
While it is generally accepted that cholesterol supersaturation of bile is of key importance in the rapid formation of cholesterol crystals, the role of total biliary protein and pH in the pathogenesis of cholesterol gallstones is less well understood ...
Ritter, Christoph von +3 more
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This report describes the synthesis of (24R)- and (24S)-24-methyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,25-tetrols and 24-ethyl-5 beta-cholestane-3 alpha,7 alpha,12 alpha,24 xi-tetrol starting from cholic acid.
B Dayal +4 more
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Chemical structures of vertebrate bile alcohols, bile acids, and vitamin D receptor ligands.
(A) The structure of cholesterol, from which all bile acids and alcohols are derived. The left panel (B-D) depicts representative bile alcohols: (B) 5α-petromyzonol, a C24 bile alcohol that is a unique and minor component of the lamprey bile alcohol pool,
David M. Reif (218469) +5 more
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Cholesterol nucleation time in gallbladder bile of patients with solitary or multiple cholesterol gallstones [PDF]
Patients with multiple cholesterol gallbladder stones have been found to be at a higher risk for the recurrence of gallstones after successful nonsurgical treatment than those with a solitary stone.
Ritter, Christoph von +4 more
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Bile acid synthesis from cholesterol is tightly regulated via a feedback mechanism mediated by the farnesoid X receptor (FXR), a nuclear receptor activated by bile acids.
Tomoko Nishimaki-Mogami +7 more
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Bile acids: analysis in biological fluids and tissues
The formation of bile acids/bile alcohols is of major importance for the maintenance of cholesterol homeostasis. Besides their functions in lipid absorption, bile acids/bile alcohols are regulatory molecules for a number of metabolic processes.
William J. Griffiths, Jan Sjövall
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Cerebrotendinous xanthomatosis (CTX) is a rare, recessively inherited lipid storage disease characterized by a markedly reduced production of chenodeoxycholic acid and an increased formation of 25-hydroxylated bile alcohols and cholestanol. Patients with
Akira Honda +9 more
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Biliary and urinary bile alcohol and bile acid composition has been determined by high performance liquid chromatography in patients with cerebrotendinous xanthomatosis before and after treatment with chenodeoxycholic acid.
A K Batta, S Shefer, M Batta, G Salen
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Increased urinary excretion of bile alcohol glucuronides in patients with primary biliary cirrhosis.
The bile alcohol glucuronides in urine of 12 patients with primary biliary cirrhosis (PBC), 10 patients with chronic active hepatitis (CAH), and 6 healthy volunteers were analyzed by capillary gas-liquid chromatography-mass spectrometry.
S Weydert-Huijghebaert +3 more
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