Results 61 to 70 of about 44,525 (313)

Resectable Cholangiocarcinoma: Reviewing the Role of Adjuvant Strategies

Clinical Medicine Insights: Oncology, 2016
Cholangiocarcinoma is a very heterogeneous and rare group of neoplasms originating from the perihilar, intra-, or extrahepatic bile duct epithelium.
E. Una Cidon
doaj   +1 more source

Local excision as a treatment for tumors of ampulla of Vater [PDF]

, 2006
Background Although local excision (ampullectomy) was first described by Halsted in 1899, its adequacy as an alternative surgical treatment for the ampullary tumors is still a matter of debate.
Haralampos Demetriades, Emmanouil Zacharakis, Ioanna Kirou, Manousos-Georgios Pramateftakis, Nikolaos Sapidis, Ioannis Kanellos, Dimitrios Betsis   +6 more
core   +2 more sources

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Biliary cystadenoma and choledochal polyp: a rare association [PDF]

Journal of Clinical and Scientific Research, 2013
Biliary cystadenomas are rare, potentially malignant neoplasms of biliary origin occurring predominantly in middle aged women. Here we report a case of biliary cystadenoma in a young female who presented with an epigastric mass and features of ...
A.Y. Lakshmi, B.Vijayalakshmi Devi, P. Sriram, M. Kumaraswamy Reddy   +3 more
doaj  

Clinical evaluation, imaging studies, indications for cytologic study, and preprocedural requirements for duct brushing studies and pancreatic FNA: The papanicolaou society of cytopathology recommendations for pancreatic and biliary cytology [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106723/1/dc23095 ...
Al-Haddad, Anand, Baron, Berg, Bhutani, Bottrell, Boyle, Braddock, Bret, Cascinu, Choi, Chong, Coley, Cotton, Dawes, Dupuy, Early, Eloubeidi, Freeny, Freeny, Freeny, Fuhrman, Greenfield, Hollett, Hopper, Horwhat, Howard, Ichikawa, Jubelirer, Karlson, Khalid, Lees, Legmann, Legmann, McCarthy, Megibow, Mertz, Micames, Midwinter, Midwinter, Müller, Novick, Palazzo, Patel, Pizzi, Reuther, Rodgers, Sahani, Shmulewitz, Siqueira, Steinberg, Steiner, Stewart, Tanaka, Tanaka, Taylor, Tomiyama, Vedantham, Vellet, Vitellas, Walsh, Warshaw, Whitney, Yoshimi   +63 more
core   +1 more source

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

Long-Term Risks of Benign and Malign Complications after Endoscopic Sphincterotomy in the Management of Benign Biliopancreatic Pathology: A Cohort Study

Eurasian Journal of Medicine
Background: Endoscopic retrograde cholangiopancreatography (ERCP) is the preferred technique for treating pathologies of the bile duct. It has been suggested that this procedure, combined with sphincterotomy, may influence the subsequent development of ...
Mercedes Ibáñez, Cristina López, Jeancarlos Trujillo , Juan Ramón Gómez , Carlos Vaquero Puerta, Juan Carlos Martin del Olmo   +5 more
doaj   +1 more source

Mixed adenoneuroendocrine carcinoma of the extrahepatic bile duct: a case report

Journal of International Medical Research, 2019
Background The concept of mixed adenoneuroendocrine carcinoma (MANEC) was introduced in the 2010 World Health Organization classification of digestive neuroendocrine neoplasms. Bile duct invasion by MANEC is exceptionally rare. We herein report a case of
Hai-Wen Zhang, Kai Kou, Jun Qi, En-Bo Xie, Meng Wang, Yan Li, Guo-Yue Lv, Guang-Yi Wang   +7 more
doaj   +1 more source

Large Cell Neuroendocrine Carcinoma of the Extrahepatic Bile Duct

The Korean Journal of Gastroenterology, 2018
Primary neuroendocrine tumors originating from the extrahepatic bile duct are rare. Among these tumors, large cell neuroendocrine carcinomas (NECs) are extremely rare.
Ji Young Park, Tae Joo Jeon
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source