Results 81 to 90 of about 38,616 (261)

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Idiopathic Vanishing Bile Duct Syndrome in a Young Female: A Case Report

The Korean Journal of Gastroenterology
Vanishing bile duct syndrome (VBDS) is characterized by the progressive loss and destruction of the intrahepatic bile ducts, leading to bile stasis and associated symptoms such as jaundice.
Min Ji Kim, Hyun Myung Cho, Young Mi Hong, Ki Tae Yoon   +3 more
doaj   +1 more source

Patterns of failure after resection of extrahepatic bile duct cancer: implications for adjuvant radiotherapy indication and treatment volumes

Radiation Oncology, 2018
Background The role of adjuvant radiotherapy (RT) and setting proper RT target volumes have not been clearly demonstrated for extrahepatic bile duct (EHBD) cancer, due to the rarity of the disease and the lack of randomized trials.
Hoon Sik Choi, Ki Mun Kang, Bae Kwon Jeong, Hojin Jeong, Yun Hee Lee, In Bong Ha, Tae Gyu Kim, Jin Ho Song   +7 more
doaj   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Total Pancreatectomy for Ampullary Adenocarcinoma in a 74-Year-Old Patient: Case Report and Literature Review

Case Reports in Surgery, 2020
Primary ampullary neoplasms have origin in the ampulla of Vater, an anatomical structure where the common bile duct and the pancreatic duct join together as a common channel. It represents
Gabriela A. Arroyo Murillo, Eleonore Choppin De Janvry, Manuela Garofalo, Fatima Della Pietra   +3 more
doaj   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Accuracy of Contrast-Enhanced Ultrasound in the Diagnosis of Bile Duct Obstruction

Ultrasound International Open, 2015
Purpose: To investigate the ability of contrast-enhanced ultrasound (CEUS) to differentiate benign from malignant lesions causing biliary duct obstruction.
F. J. P. Fontán, Á. R. Reboredo, A. R. Siso   +2 more
doaj   +1 more source

A Serous Cystadenocarcinoma of the Pancreas Diagnosed With Lymph Node Metastasis

Acta Medica Iranica, 2019
Serous cystic neoplasms of the pancreas account for 10% to 16% of all pancreatic cystic masses. Serous cystic neoplasms were evaluated as benign pancreatic masses.
Mustafa Ozsoy, Cigdem Ozdemir, Zehra Ozsoy, Sezgin Yilmaz, Yuksel Aeikan   +4 more
doaj  

Total duodeno-pancreatectomy for intraductal papillary and mucinous tumor of the pancreas: report of a complex case.

Batna Journal of Medical Sciences
Intraductal papillary mucinous neoplasms of the pancreas (IPMNs) are rare cystic neoplasms with significant malignant potential. Treatment is primarily based on surgical resection, tailored to the patient’s radiological and clinical profile.
Youcef KHENCHOUL, Hichem El Azhari BENMAMAR, Mustapha BOUMENDJEL, Dalel ZERROUK, Imen HAMIOUDA   +4 more
doaj   +1 more source

Intraductal papillary neoplasm of the bile duct

, 2022
La neoplasia papilar intraductal de la vía biliar (NPIVB) es una entidad infrecuente caracterizada por el crecimiento exofítico papilar del epitelio biliar hacia la luz ductal. Previamente incluida en el grupo de tumores del mismo nombre de localización pancreática, presenta diferencias evidentes con ellos y desde 2010 se considera una entidad propia ...
Pierini, Ángel, Pierini, Leandro, Ruiz, Guillermo, Evans Rhys, Brian, Elias, Juan Pablo, Meneghini, Rodrigo   +5 more
openaire   +1 more source