Results 71 to 80 of about 38,809 (261)

Extrahepatic Cholangiocarcinoma in an adult Black Howler Monkey (Primates: Atelidae)

Brazilian Journal of Veterinary Medicine, 2019
Over the past years, the number of neoplasm cases reported in nonhuman primates have considerably increased, with hepatocellular tumors reported in several species.
Mariele de Santi, CAROLINE DO COUTO, GABRIEL LUIZ MONTANHIM, PAOLA CASTRO MORAES, PAULO HENRIQUE LEAL BERTOLO, ROSEMERI DE OLIVEIRA VASCONCELOS, ACÁCIA REBELLO COUTINHO, KARIN WERTHER   +7 more
doaj   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

A Case of Adenomyomatous Hyperplasia of the Distal Common Bile Duct Mimicking Malignant Stricture

The Korean Journal of Gastroenterology, 2016
Adenomyomatous hyperplasia is a reactive malformation or non-neoplastic tumor-like lesion frequently observed in the gallbladder, stomach, duodenum and jejunum, but rare in the extrahepatic bile duct.
Jin Ho Choi, Sang Hyub Lee, Joo Seong Kim, Jung Kim, Bang-sup Shin, Dong Kee Jang, Ji Kon Ryu, Yong-Tae Kim   +7 more
doaj   +1 more source

Genetic Tracing of Clonal Expansion and Progression of Pancreatic Ductal Adenocarcinoma: A Case Report and Multi-Region Sequencing Analysis

Frontiers in Oncology, 2020
Pancreatobiliary tumors frequently contain multiple malignant and precancerous lesions; however, the origin of the driver mutations and the mechanisms that underlie the generation of distinct clones within an organ field remain unclear.
Shion Tachibana, Shion Tachibana, Shion Tachibana, Yusuke Mizukami, Yusuke Mizukami, Yusuke Ono, Yusuke Ono, Yuya Sugiyama, Yuya Sugiyama, Tetsuhiro Okada, Tetsuhiro Okada, Arisa Kitazaki, Junpei Sasajima, Junpei Sasajima, Motoya Tominaga, Jun Sakamoto, Keisuke Kimura, Yuko Omori, Toru Furukawa, Taichi Kimura, Shinya Tanaka, Kazuo Nagashima, Hidenori Karasaki, Tomoyuki Ohta, Toshikatsu Okumura   +24 more
doaj   +1 more source

Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments—A VigiBase Disproportionality Analysis Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian, Floriane Jochum, Elise Dumas, Florence Coussy, Kevin Bihan, Bénédicte Lebrun‐Vignes, Barbara Pistilli, Marc‐Antoine Benderra, Lise Selleret, Laurent Chouchana, Fabien Reyal, Anne‐Sophie Hamy, Paul Gougis   +12 more
wiley   +1 more source

Cholangioscopy-guided ERCP: expanding diagnostic and therapeutic applications

Frontiers in Medicine
Endoscopic retrograde cholangiopancreatography (ERCP) remains a cornerstone technique for the management of pancreaticobiliary diseases, but conventional ERCP relies largely on fluoroscopic images and cannot directly evaluate intraductal mucosal ...
Shengjie Yang, Hongyu Li
doaj   +1 more source

Cystic and Papillary Neoplasm at the Hepatic Hilum Possibly Originating in the Peribiliary Glands

Case Reports in Pathology, 2016
Cystic neoplasms of the liver are divided into two types: mucinous cystic neoplasm and cystic intraductal papillary neoplasm of the bile duct. We herein report two cases of cystic and papillary neoplasm of the liver which differed from the abovementioned
Takashi Miyata, Katsuhiko Uesaka, Yasuni Nakanuma   +2 more
doaj   +1 more source

Two cases of cholangiocarcinoma in diabetes mellitus causing worsening of glycemic control and acute liver dysfunction

Journal of Clinical and Translational Endocrinology Case Reports, 2018
This is a report of 2 cases of sudden and simultaneous worsening of glycemic control and acute liver dysfunction (biliary obstruction) suggestive of extrahepatic cholangiocarcinoma (ECC). Case 1 was a 59-year-old woman with a history of diabetes mellitus,
Masaru Oota
doaj   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Poorly Cohesive Carcinoma of Common Bile Duct: A Rare Histological Type of Cholangiocarcinoma

Clinical Medicine Insights: Case Reports
Biliary tract carcinomas (BTC) are malignant epithelial neoplasms subdivided anatomically into: gallbladder carcinomas and carcinomas of the bile duct or cholangiocarcinomas (CCA); including intrahepatic, hilar/perihilar, and distal CCA.
Derqaoui Sabrine, Hamid Mohamed, Ahmed jahid, Kaoutar Znati, Fouad Zouaidia, Settaf Abdellatif, Bernoussi Zakiya   +6 more
doaj   +1 more source