Results 71 to 80 of about 38,616 (261)

Extrahepatic Cholangiocarcinoma in an adult Black Howler Monkey (Primates: Atelidae)

Brazilian Journal of Veterinary Medicine, 2019
Over the past years, the number of neoplasm cases reported in nonhuman primates have considerably increased, with hepatocellular tumors reported in several species.
Mariele de Santi, CAROLINE DO COUTO, GABRIEL LUIZ MONTANHIM, PAOLA CASTRO MORAES, PAULO HENRIQUE LEAL BERTOLO, ROSEMERI DE OLIVEIRA VASCONCELOS, ACÁCIA REBELLO COUTINHO, KARIN WERTHER   +7 more
doaj   +1 more source

Genetic Tracing of Clonal Expansion and Progression of Pancreatic Ductal Adenocarcinoma: A Case Report and Multi-Region Sequencing Analysis

Frontiers in Oncology, 2020
Pancreatobiliary tumors frequently contain multiple malignant and precancerous lesions; however, the origin of the driver mutations and the mechanisms that underlie the generation of distinct clones within an organ field remain unclear.
Shion Tachibana, Shion Tachibana, Shion Tachibana, Yusuke Mizukami, Yusuke Mizukami, Yusuke Ono, Yusuke Ono, Yuya Sugiyama, Yuya Sugiyama, Tetsuhiro Okada, Tetsuhiro Okada, Arisa Kitazaki, Junpei Sasajima, Junpei Sasajima, Motoya Tominaga, Jun Sakamoto, Keisuke Kimura, Yuko Omori, Toru Furukawa, Taichi Kimura, Shinya Tanaka, Kazuo Nagashima, Hidenori Karasaki, Tomoyuki Ohta, Toshikatsu Okumura   +24 more
doaj   +1 more source

Pylorus‐Preserving Gastrectomy for Gastric Cancer: Current Evidence and Future Directions

Annals of Gastroenterological Surgery, EarlyView.
This review aims to outline the current evidence and future directions of PPG, focusing on the feasibility of extending its application beyond its traditional indications. ABSTRACT Pylorus‐preserving gastrectomy (PPG) is a function‐preserving surgery for clinically T1N0M0 (cT1N0M0) early gastric cancer (EGC) located in the middle third of the stomach ...
Sa‐Hong Kim, Hyuk‐Joon Lee
wiley   +1 more source

Cystic and Papillary Neoplasm at the Hepatic Hilum Possibly Originating in the Peribiliary Glands

Case Reports in Pathology, 2016
Cystic neoplasms of the liver are divided into two types: mucinous cystic neoplasm and cystic intraductal papillary neoplasm of the bile duct. We herein report two cases of cystic and papillary neoplasm of the liver which differed from the abovementioned
Takashi Miyata, Katsuhiko Uesaka, Yasuni Nakanuma   +2 more
doaj   +1 more source

Two cases of cholangiocarcinoma in diabetes mellitus causing worsening of glycemic control and acute liver dysfunction

Journal of Clinical and Translational Endocrinology Case Reports, 2018
This is a report of 2 cases of sudden and simultaneous worsening of glycemic control and acute liver dysfunction (biliary obstruction) suggestive of extrahepatic cholangiocarcinoma (ECC). Case 1 was a 59-year-old woman with a history of diabetes mellitus,
Masaru Oota
doaj   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Developmental Characteristics of the Embryonic Liver Tissue and Long‐Term Culture of Primary Hepatocytes in Duck

Animal Research and One Health, EarlyView.
Liver development was investigated at different embryonic ages (EAs). Furthermore, numerous hepatocyte media were formulated and evaluated. These results could elaborate the developmental characteristics of duck liver tissue and determine the most suitable medium for the proliferation and characteristic maintenance of hepatocytes in vitro, which would ...
Jie Wei, Jing Tang, Bo Zhang, Chenchen Du, Yunsheng Zhang, Ming Xie, Zhengkui Zhou, Shuisheng Hou   +7 more
wiley   +1 more source

Poorly Cohesive Carcinoma of Common Bile Duct: A Rare Histological Type of Cholangiocarcinoma

Clinical Medicine Insights: Case Reports
Biliary tract carcinomas (BTC) are malignant epithelial neoplasms subdivided anatomically into: gallbladder carcinomas and carcinomas of the bile duct or cholangiocarcinomas (CCA); including intrahepatic, hilar/perihilar, and distal CCA.
Derqaoui Sabrine, Hamid Mohamed, Ahmed jahid, Kaoutar Znati, Fouad Zouaidia, Settaf Abdellatif, Bernoussi Zakiya   +6 more
doaj   +1 more source

Episodic Biliary Obstruction: Intrahepatic Biliary Cystadenoma

Archives of Clinical and Experimental Surgery, 2014
Biliary cystadenomas are rare, benign but potentially malignant, multilocular, cystic neoplasms of a biliary origin. They often present with non-specific symptoms.
Ashwin Rammohan, Jeswanth Sathyanesan, Ravichandran Palaniappan   +2 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source