Results 81 to 90 of about 44,112 (353)

Magnetoelectric Nanotherapy Achieves Complete Tumor Ablation and Prolonged Survival in Pancreatic Cancer Murine Models

Advanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) serve as externally controlled, MRI‐activated theranostic agents for targeted cancer therapy by inducing electric field‐based ablation in solid tumors. MENPs enable simultaneous precise tumor ablation and MRI signal modulation, allowing real‐time treatment monitoring and prediction of therapeutic outcomes with no ...
John Michael Bryant, Max Shotbolt, Emmanuel Stimphil, Victoria Andre, Elric Zhang, Veronica Estrella, Kazim Husain, Joseph Weygand, Doug Marchion, Alex Sebastian Lopez, Dominique Abrahams, Shawnus Chen, Mostafa Abdel‐Mottaleb, Skye Conlan, Ibrahim Oraiqat, Vaseem Khatri, Jose Alejandro Guevara, Shari Pilon‐Thomas, Gage Redler, Kujtim Latifi, Natarajan Raghunand, Kosj Yamoah, Sarah Hoffe, James Costello, Jessica M. Frakes, Ping Liang, Robert A. Gatenby, Mokenge Malafa, Sakhrat Khizroev   +28 more
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Extrahepatic Cholangiocarcinoma in an adult Black Howler Monkey (Primates: Atelidae)

Brazilian Journal of Veterinary Medicine, 2019
Over the past years, the number of neoplasm cases reported in nonhuman primates have considerably increased, with hepatocellular tumors reported in several species.
Mariele de Santi, CAROLINE DO COUTO, GABRIEL LUIZ MONTANHIM, PAOLA CASTRO MORAES, PAULO HENRIQUE LEAL BERTOLO, ROSEMERI DE OLIVEIRA VASCONCELOS, ACÁCIA REBELLO COUTINHO, KARIN WERTHER   +7 more
doaj   +1 more source

Treatment of hilar cholangiocarcinoma (Klatskin tumors) with hepatic resection or transplantation [PDF]

, 1998
Background: Because of the rarity of hilar cholangiocarcinoma, its prognostic risk factors have not been sufficiently analyzed. This retrospective study was undertaken to evaluate various pathologic risk factors which influenced survival after curative ...
Dvorchik, I, Fung, JJ, Iwatsuki, S, Lee, RG, Madariaga, JR, Marsh, JW, Starzl, TE, Todo, S   +7 more
core   +1 more source

Immediate Reconstruction of Pancretaticogastrostomy Following Hepatopancreatoduodenectomy for Biliary Tact Cancer: A Single‐Center Review of 33 Consecutive Patients

Annals of Gastroenterological Surgery, EarlyView.
This study showed that the pancreaticogastrostomy technique in HPD of biliary tract cancer reduced the incidence of pancreatic fistula from 45% to 12%. In‐hospital mortality was also reduced from 27% to 3%. ABSTRACT Background and Purpose Although hepatopancreaticoduodenectomy (HPD) is effective for margin‐negative curative resection of biliary tract ...
Ryusei Matsuyama, Yasuhiro Yabusita, Tomoaki Takahashi, Yutaro Kikuchi, Kouta Sahara, Kentaro Miyake, Yu Sawada, Yuuki Homma, Takafumi Kumamoto, Itaru Endo   +9 more
wiley   +1 more source

CD8+ T cell memory is sustained in mice by hepatic stellate cells

Hepatology, EarlyView., 2022
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen, Yu‐Chia Su, Yee‐Ern Or, Chin‐Fu Cheng, John T. Kung   +4 more
wiley   +1 more source

A Case of Adenomyomatous Hyperplasia of the Distal Common Bile Duct Mimicking Malignant Stricture

The Korean Journal of Gastroenterology, 2016
Adenomyomatous hyperplasia is a reactive malformation or non-neoplastic tumor-like lesion frequently observed in the gallbladder, stomach, duodenum and jejunum, but rare in the extrahepatic bile duct.
Jin Ho Choi, Sang Hyub Lee, Joo Seong Kim, Jung Kim, Bang-sup Shin, Dong Kee Jang, Ji Kon Ryu, Yong-Tae Kim   +7 more
doaj   +1 more source

Genetic Tracing of Clonal Expansion and Progression of Pancreatic Ductal Adenocarcinoma: A Case Report and Multi-Region Sequencing Analysis

Frontiers in Oncology, 2020
Pancreatobiliary tumors frequently contain multiple malignant and precancerous lesions; however, the origin of the driver mutations and the mechanisms that underlie the generation of distinct clones within an organ field remain unclear.
Shion Tachibana, Shion Tachibana, Shion Tachibana, Yusuke Mizukami, Yusuke Mizukami, Yusuke Ono, Yusuke Ono, Yuya Sugiyama, Yuya Sugiyama, Tetsuhiro Okada, Tetsuhiro Okada, Arisa Kitazaki, Junpei Sasajima, Junpei Sasajima, Motoya Tominaga, Jun Sakamoto, Keisuke Kimura, Yuko Omori, Toru Furukawa, Taichi Kimura, Shinya Tanaka, Kazuo Nagashima, Hidenori Karasaki, Tomoyuki Ohta, Toshikatsu Okumura   +24 more
doaj   +1 more source

Left hepatic trisegmentectomy [PDF]

, 1982
Left hepatic trisegmentectomy was successfully performed upon four patients in whom the true left lobe of the liver and all, or part, of the anterior segment of the right lobe of the liver were removed in continuity.
Bron, KM, Dekker, A, Diliz, HS, Iwatsuki, SI, Shaw, BW, Starzl, TE, Van Thiel, D, Waterman, PM   +7 more
core  

Essential Updates 2023/2024: Minimally Invasive Surgery for Biliary Tract Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Minimally invasive surgery (MIS) for biliary tract cancer (BTC) has gained traction with advancements in laparoscopic and robotic techniques. However, its oncological impact remains uncertain. This review highlights key studies from 2023 and 2024 on MIS for BTC, including distal bile duct, hilar bile duct, gallbladder, and intrahepatic bile ...
Osamu Itano, Takuya Minagawa
wiley   +1 more source