The emerging roles of UFMylation in the modulation of immune responses. [PDF]
UFMylation regulates cGAS‐STING and RIG‐I pathways to defend pathogens. UFMylation regulates the PD‐1/PD‐L1 checkpoint. UFMylation component UFBP1 regulates the function of B cells. UFMylation regulates inflammation‐related pathways (e.g., TLRs and NF‐κB).
Liang Z +9 more
europepmc +2 more sources
Detection of EBV Infection and Gene Expression in Oral Cancer from Patients in Taiwan by Microarray Analysis [PDF]
Epstein‐Barr virus is known to cause nasopharyngeal carcinoma. Although oral cavity is located close to the nasal pharynx, the pathogenetic role of Epstein‐Barr virus (EBV) in oral cancers is unclear. This molecular epidemiology study uses EBV genomic microarray (EBV‐chip) to simultaneously detect the prevalent rate and viral gene expression patterns ...
Ching-Yu Yen +9 more
core +2 more sources
Latent DNA viruses disrupt the cell cycle and alter several colorectal cancer‐related regulatory proteins and signalling pathways, including the induction of mutations. Some bacteria contribute to foster a pro‐oncogenic microenvironment, further laying the ground for the establishment of CRC.
Luigi Marongiu, Heike Allgayer
wiley +1 more source
Abstract Exploitation of heterosis between indica and japonica has important significance in scientific research and agriculture application. However, the molecular mechanism of grain shape heterosis in indica–japonica hybrid remains unknown in rice (Oryza sativa L.).
Xiaoxiao Deng +8 more
wiley +1 more source
Comprehensive evolutionary analysis of complete Epstein Barr virus genomes from Argentina and other geographies [PDF]
The sequence variability of the Epstein–Barr virus has been extensively studied throughout previous years in isolates from various geographic regions and consequent variations at both genetic and genomic levels have been described. However, isolates from
Berenstein, Ariel José +8 more
core +1 more source
Clinical Features of the Course of Chronic Epstein-barr Viral Infection Depending on the Type of Immune Reaction of Organism [PDF]
The results of the study of the main regulatory cytokines levels in patients with chronic forms of EBV-infection (CEBV) are presented the work.Aim of research.
Liadova, T. (Tatiana)
core +4 more sources
The future of antiviral immunotoxins [PDF]
There is a constant need for new therapeutic interventions in a wide range of infectious diseases. Over the past few years, the immunotoxins have entered the stage as promising antiviral treatments.
Høy Jakobsen, Mette +3 more
core +1 more source
EBV BILF1 Evolved To Downregulate Cell Surface Display of a Wide Range of HLA Class I Molecules through Their Cytoplasmic Tail [PDF]
Abstract Coevolution of herpesviruses and their hosts has driven the development of both host antiviral mechanisms to detect and eliminate infected cells and viral ploys to escape immune surveillance. Among the immune-evasion strategies used by the lymphocryptovirus (γ1-herpesvirus) EBV is the downregulation of surface HLA class I ...
Griffin, B.D. +7 more
openaire +4 more sources
Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4 [PDF]
Members of the herpesviral family use multiple strategies to hijack infected host cells and exploit cellular signaling for their pathogenesis and latent infection.
Aigerim, A +14 more
core +1 more source
Complete sequence and analysis of the ovine herpesvirus 2 genome [PDF]
Ovine herpesvirus 2 (OvHV-2) is endemic in sheep populations worldwide and causes malignant catarrhal fever (MCF), a lymphoproliferative disease, in cattle, bison and deer. OvHV-2 has been placed in the gammaherpesvirus subfamily and is related closely
Ackermann, M +6 more
core +1 more source

