Results 11 to 20 of about 21,958 (289)

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

open access: yesCell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner   +8 more
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

open access: yesHepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr   +19 more
wiley   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

open access: yesHepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat   +22 more
wiley   +1 more source

Different clinical and genetic features of Alagille patients with progressive disease versus a jaundice‐free course

open access: yesJGH Open, Volume 6, Issue 12, Page 839-845, December 2022., 2022
This study highlighted the different disease courses of Alagille syndrome patients with progressive disease (PD) or the jaundice‐free (JF) courses based on clinical follow‐up. Patients in the JF group had a favorable outcome and longer native liver survival than the PD group.
Che‐Ming Chiang   +13 more
wiley   +1 more source

Prognosis of Biliary Atresia Associated With Cytomegalovirus: A Meta-Analysis

open access: yesFrontiers in Pediatrics, 2021
Objective: The etiology of biliary atresia is unclear, but viral infection has been implicated. The aim of the current meta-analysis was to investigate relationships between cytomegalovirus (CMV) and the prognosis of biliary atresia.Methods: PubMed ...
Yilin Zhao   +8 more
doaj   +1 more source

Value of the International Classification of Diseases code for identifying children with biliary atresia [PDF]

open access: yesClinical and Experimental Pediatrics, 2021
Background Although identifying cases in large administrative databases may aid future research studies, previous reports demonstrated that the use of the International Classification of Diseases, Tenth Revision (ICD-10) code alone for diagnosis leads to
Pornthep Tanpowpong   +3 more
doaj   +1 more source

Cold plasma endoscopy applied to biliary ducts: feasibility risk assessment on human-like and porcine models for the treatment of cholangiocarcinoma [PDF]

open access: yesJ. Phys. D. Appl. Phys., Vol. 55, No 45, 2022, 2023
For the past twelve years, cold plasmas have been positioned as a breakthrough technology for treating cancer thanks to their antitumor properties. The innovation of ad hoc plasma sources and personalized protocols appears crucial to treat cancers with a very poor prognosis.
arxiv   +1 more source

Waitlist mortality of young patients with biliary atresia: Impact of allocation policy and living donor liver transplantation

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Patients with biliary atresia (BA) below 2 years of age in need of a transplantation largely rely on partial grafts from deceased donors (deceased donor liver transplantation [DDLT]) or living donors (living donor liver transplantation [LDLT]).
Hedayatullah Esmati   +10 more
wiley   +1 more source

Nilai Diagnostik Ultrasonografi Hepatobilier sebagai Prediktor Atresiabilier pada Kolestasis Bayi di RSUP Sanglah Denpasar Tahun 2017 - 2021

open access: yesJurnal Kesehatan Andalas, 2023
Hepatobiliary ultrasound is the most common initial diagnostic modality in the early detection of biliary atresia. It is not the gold standard, but the hepatobiliary ultrasound examination can be used to determine the appropriate further management ...
Kristin Agustina   +5 more
doaj   +1 more source

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