Results 21 to 30 of about 141,658 (207)

KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H 2S axis and contributes to pancreatic cancer growth

open access: yesActa Biochimica et Biophysica Sinica, 2022
In pancreatic cancer, KRAS G12D can trigger pancreatic cancer initiation and development. Rapid tumor growth is often accompanied by excess intracellular reactive oxygen species (ROS) production, which is unfavorable to tumor.
Fan Kun   +9 more
doaj   +1 more source

The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]

open access: yes, 2019
Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A.   +8 more
core   +1 more source

Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]

open access: yes, 2018
The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O   +9 more
core   +2 more sources

Hemobilia from biliary angiodysplasia diagnosed with cholangioscopy [PDF]

open access: yes, 2016
Biliary angiodysplasia is extremely rare. Our background search revealed only a few case reports in the English literature. We present a case of angiodysplasia of the proximal common bile duct in a patient with subacute upper gastrointestinal bleeding ...
Foong, Kap Sum   +3 more
core   +2 more sources

Non-invasive detection of biliary tract cancer by low-coverage whole genome sequencing from plasma cell-free DNA: A prospective cohort study

open access: yesTranslational Oncology, 2021
Background: The diagnosis of biliary tract cancer (BTC) is challenging in clinical practice. We performed a prospective study to evaluate the value of plasma copy number variation (CNV) assays in diagnosing BTC.
Xiang Wang   +9 more
doaj   +1 more source

Biliary drainage in malignant biliary obstruction: an umbrella review of randomized controlled trials

open access: yesFrontiers in Oncology, 2023
BackgroundThere are still many controversies about biliary drainage in MBO, and we aimed to summarize and evaluate the evidence associated with biliary drainage.MethodsWe conducted an umbrella review of SRoMAs based on RCTs. Through July 28, 2022, Embase,
Yaoqun Wang   +8 more
doaj   +1 more source

Biliary Tract Carcinoma

open access: yesUpsala Journal of Medical Sciences, 1980
A series of 127 patients treated for cancer of the biliary tract during the period 1965-1974 was studied with a follow-up period of at least five years. The mean age was 66 years and the female:male ratio was 3:1. An early diagnosis of biliary tract carcinoma is difficult and the prognosis unfavourable although not hopeless.
V, Skoog, L, Thorén
openaire   +2 more sources

Radiation therapy for primary carcinoma of the extrahepatic biliary system. An analysis of 63 cases. [PDF]

open access: yes, 1991
From 1976 to 1988, 63 patients received radiation therapy for primary cancers of the extrahepatic biliary system (eight gallbladder and 55 extrahepatic biliary duct). Twelve patients underwent orthotopic liver transplantation.
Carr, BI   +4 more
core   +1 more source

Additional BCAA-enriched nutrient mixture improves the nutritional condition in cirrhotic patients with hypoalbuminemia despite treatment with regular BCAA granules: A pilot study

open access: yesThe Turkish Journal of Gastroenterology, 2015
Background/Aims: To elucidate the effect of adding branched-chain amino acid (BCAA)-enriched nutrient mixtures in cirrhotic patients with hypoalbuminemia despite the use of BCAA granules. Materials and Methods: A BCAA-enriched nutrient mixture containing
Aiko Fukui   +11 more
doaj   +1 more source

Transplantation in children [PDF]

open access: yes, 1976
Kidney transplantation in very young children, less than 2 years of age, has usually failed, mainly because of difficulties maintaining these patients on hemodialysis long enough to permit retransplantation after loss of the original graft.
Charles W. Putnam   +15 more
core   +1 more source

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