Results 21 to 30 of about 1,047,340 (417)

Establishment and characterization of an immortalized epithelial cell line from human gallbladder

Frontiers in Oncology, 2022
BackgroundAlthough a plethora of studies have employed multiple gallbladder cancer (GBC) cell lines, it is surprisingly noted that there is still lack of a normal gallbladder epithelial cell line as a normal counterpart, thus impeding substantially the ...
Ziyi Wang, Ziyi Wang, Ziyi Wang, Ziyi Wang, Shijia Wang, Shijia Wang, Shijia Wang, Shijia Wang, Ziheng Jia, Ziheng Jia, Ziheng Jia, Ziheng Jia, Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Mao Yang, Mao Yang, Mao Yang, Mao Yang, Weikang Yan, Weikang Yan, Weikang Yan, Weikang Yan, Tao Chen, Tao Chen, Tao Chen, Tao Chen, Dongxi Xiang, Dongxi Xiang, Dongxi Xiang, Rong Shao, Rong Shao, Rong Shao, Rong Shao, Rong Shao, Yingbin Liu, Yingbin Liu, Yingbin Liu, Yingbin Liu   +39 more
doaj   +1 more source

The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct interaction with YAP1

Journal of Translational Medicine, 2023
Background Gallbladder cancer (GBC) is the most prevalent and invasive biliary tract malignancy. As a GTPase-activating protein, Neurofibromin 1 (NF1) is a tumor suppressor that negatively regulates the RAS signaling pathway, and its abnormality leads to
Lingxiao Zhang, Lin Jiang, Ling Zeng, Zhaohui Jin, Xuanjia Dong, Yuhan Zhang, Litian Chen, Yijun Shu, Yingbin Liu, Ying Huang   +9 more
doaj   +1 more source

Development and Validation of a Prognostic Nomogram Based on the Systemic Immune-Inflammation Index for Resectable Gallbladder Cancer to Predict Survival and Chemotherapy Benefit

Frontiers in Oncology, 2021
ObjectivesTo investigate the prognostic significance of the systemic immune-inflammation index (SII) in patients after radical cholecystectomy for gallbladder cancer (GBC) using overall survival (OS) as the primary outcome measure.MethodsBased on data ...
Lin Li, Lin Li, Lin Li, Lin Li, Tai Ren, Tai Ren, Tai Ren, Ke Liu, Ke Liu, Ke Liu, Ke Liu, Mao-Lan Li, Mao-Lan Li, Mao-Lan Li, Ya-Jun Geng, Ya-Jun Geng, Ya-Jun Geng, Ya-Jun Geng, Yang Yang, Yang Yang, Yang Yang, Yang Yang, Huai-Feng Li, Huai-Feng Li, Huai-Feng Li, Xue-Chuan Li, Xue-Chuan Li, Xue-Chuan Li, Xue-Chuan Li, Run-Fa Bao, Run-Fa Bao, Run-Fa Bao, Yi-Jun Shu, Yi-Jun Shu, Yi-Jun Shu, Hao Weng, Hao Weng, Hao Weng, Wei Gong, Wei Gong, Wei Gong, Wan Yee Lau, Xiang-Song Wu, Xiang-Song Wu, Xiang-Song Wu, Ying-Bin Liu, Ying-Bin Liu, Ying-Bin Liu, Ying-Bin Liu   +48 more
doaj   +1 more source

Mutational spectrum and precision oncology for biliary tract carcinoma

Theranostics, 2021
Background: The genomic spectrum of biliary tract carcinoma (BTC) has been characterized and is associated with distinct anatomic and etiologic subtypes, yet limited studies have linked genomic alterations with personalized therapies in BTC patients ...
Jianzhen Lin, Yi-Ou Cao, Xu Yang, Guangyu Li, Yang Shi, Dongxu Wang, J. Long, Yang Song, J. Mao, Fucun Xie, Yi Bai, Lei Zhang, Xiaobo Yang, Xueshuai Wan, Anqiang Wang, M. Guan, Lin Zhao, K. Hu, Jie Pan, L. Huo, Xin Lu, Y. Mao, X. Sang, Henghui Zhang, Kai Wang, Xiaoyue Wang, Haitao Zhao   +26 more
semanticscholar   +1 more source

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D, Arcidiacono, Pg, Capurso, G., Cardinale, V, Carpino, G, Doglioni, C, Gaudio, E, Pedica, F, Petrone, Mc, Severi, C, Zaccari, P   +10 more
core   +1 more source

Evaluation of a 12-mm diameter covered self-expandable end bare metal stent for malignant biliary obstruction

Endoscopy International Open, 2018
Background and study aims Biliary metallic stents are used to drain unresectable malignant distal biliary obstructions. This study aimed to evaluate the efficacy of a novel 12-mm-diameter covered, self-expandable end bare metal stent (12-mm CSEEMS).
Kazunori Nakaoka, Senju Hashimoto, Naoto Kawabe, Takuji Nakano, Toshiki Kan, Masashi Ohki, Yuka Ochi, Tomoki Takamura, Takamitsu Kurashita, Sayuri Nomura, Keishi Koyama, Aiko Fukui, Kentaro Yoshioka   +12 more
doaj   +1 more source

Percutaneous transhepatic cholangiography and biliary drainage after liver transplantation: A five-year experience [PDF]

, 1987
Evaluation of the biliary tract by percutaneous transhepatic cholangiography (PTC) is often required in liver transplant patients with an abnormal postoperative course.
AB Zajko, AG Tzakis, Albert B. Zajko, David H. Thiel, DH Thiel Van, DJ Gallacher, G Martineau, J Northover, JC Gartner Jr, JJ Malatack, JMA Northover, JT Ferrucci Jr, Klaus M. Bron, Rajan Behal, RY Calne, RY Calne, S Iwatsuki, TE Starzl, TE Starzl, TE Starzl, TE Starzl, TE Starzl, TE Starzl, TE Starzl, TE Starzl, Thomas E. Starzl, W Molnar, William L. Campbell   +27 more
core   +1 more source

Evaluation of Combination Nivolumab and Ipilimumab Immunotherapy in Patients With Advanced Biliary Tract Cancers: Subgroup Analysis of a Phase 2 Nonrandomized Clinical Trial.

JAMA Oncology, 2020
Importance Biliary tract cancers represent a rare group of malignant conditions with very limited treatment options. Patients with advanced disease have a poor outcome with current therapies. Objective To evaluate the efficacy and safety of combination
O. Klein, D. Kee, A. Nagrial, B. Markman, C. Underhill, M. Michael, Louise Jackett, C. Lum, A. Behren, J. Palmer, N. Tebbutt, M. Carlino, J. Cebon   +12 more
semanticscholar   +1 more source

Congenital cystic lesions of the biliary tree [PDF]

, 2012
OBJECTIVE: The purpose of this essay is to illustrate the imaging findings of congenital cystic lesions of the biliary tract. CONCLUSION: Congenital cystic lesions of the biliary tract include ductal plate malformations and choledochal cysts and can be ...
Caseiro-Alves, F, Curvo-Semedo, L, Loureiro, R, Marques, C, Matos, C, Santiago, I, Tardáguila, F   +6 more
core   +1 more source

KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H ₂S axis and contributes to pancreatic cancer growth

Acta Biochimica et Biophysica Sinica, 2022
In pancreatic cancer, KRAS G12D can trigger pancreatic cancer initiation and development. Rapid tumor growth is often accompanied by excess intracellular reactive oxygen species (ROS) production, which is unfavorable to tumor.
Fan Kun, Zhang Shulong, Ni Xiaojian, Shen Sheng, Wang Jiwen, Sun Wentao, Suo Tao, Liu Han, Ni Xiaoling, Liu Houbao   +9 more
doaj   +1 more source