Results 21 to 30 of about 1,090,016 (327)

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D, Arcidiacono, Pg, Capurso, G., Cardinale, V, Carpino, G, Doglioni, C, Gaudio, E, Pedica, F, Petrone, Mc, Severi, C, Zaccari, P   +10 more
core   +1 more source

Evaluation of a 12-mm diameter covered self-expandable end bare metal stent for malignant biliary obstruction

Endoscopy International Open, 2018
Background and study aims Biliary metallic stents are used to drain unresectable malignant distal biliary obstructions. This study aimed to evaluate the efficacy of a novel 12-mm-diameter covered, self-expandable end bare metal stent (12-mm CSEEMS).
Kazunori Nakaoka, Senju Hashimoto, Naoto Kawabe, Takuji Nakano, Toshiki Kan, Masashi Ohki, Yuka Ochi, Tomoki Takamura, Takamitsu Kurashita, Sayuri Nomura, Keishi Koyama, Aiko Fukui, Kentaro Yoshioka   +12 more
doaj   +1 more source

Establishment and characterization of an immortalized epithelial cell line from human gallbladder

Frontiers in Oncology, 2022
BackgroundAlthough a plethora of studies have employed multiple gallbladder cancer (GBC) cell lines, it is surprisingly noted that there is still lack of a normal gallbladder epithelial cell line as a normal counterpart, thus impeding substantially the ...
Ziyi Wang, Ziyi Wang, Ziyi Wang, Ziyi Wang, Shijia Wang, Shijia Wang, Shijia Wang, Shijia Wang, Ziheng Jia, Ziheng Jia, Ziheng Jia, Ziheng Jia, Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Yuhao Zhao, Mao Yang, Mao Yang, Mao Yang, Mao Yang, Weikang Yan, Weikang Yan, Weikang Yan, Weikang Yan, Tao Chen, Tao Chen, Tao Chen, Tao Chen, Dongxi Xiang, Dongxi Xiang, Dongxi Xiang, Rong Shao, Rong Shao, Rong Shao, Rong Shao, Rong Shao, Yingbin Liu, Yingbin Liu, Yingbin Liu, Yingbin Liu   +39 more
doaj   +1 more source

The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct interaction with YAP1

Journal of Translational Medicine, 2023
Background Gallbladder cancer (GBC) is the most prevalent and invasive biliary tract malignancy. As a GTPase-activating protein, Neurofibromin 1 (NF1) is a tumor suppressor that negatively regulates the RAS signaling pathway, and its abnormality leads to
Lingxiao Zhang, Lin Jiang, Ling Zeng, Zhaohui Jin, Xuanjia Dong, Yuhan Zhang, Litian Chen, Yijun Shu, Yingbin Liu, Ying Huang   +9 more
doaj   +1 more source

Mutational spectrum and precision oncology for biliary tract carcinoma

Theranostics, 2021
Background: The genomic spectrum of biliary tract carcinoma (BTC) has been characterized and is associated with distinct anatomic and etiologic subtypes, yet limited studies have linked genomic alterations with personalized therapies in BTC patients ...
Jianzhen Lin, Yi-Ou Cao, Xu Yang, Guangyu Li, Yang Shi, Dongxu Wang, J. Long, Yang Song, J. Mao, Fucun Xie, Yi Bai, Lei Zhang, Xiaobo Yang, Xueshuai Wan, Anqiang Wang, M. Guan, Lin Zhao, K. Hu, Jie Pan, L. Huo, Xin Lu, Y. Mao, X. Sang, Henghui Zhang, Kai Wang, Xiaoyue Wang, Haitao Zhao   +26 more
semanticscholar   +1 more source

Development and Validation of a Prognostic Nomogram Based on the Systemic Immune-Inflammation Index for Resectable Gallbladder Cancer to Predict Survival and Chemotherapy Benefit

Frontiers in Oncology, 2021
ObjectivesTo investigate the prognostic significance of the systemic immune-inflammation index (SII) in patients after radical cholecystectomy for gallbladder cancer (GBC) using overall survival (OS) as the primary outcome measure.MethodsBased on data ...
Lin Li, Lin Li, Lin Li, Lin Li, Tai Ren, Tai Ren, Tai Ren, Ke Liu, Ke Liu, Ke Liu, Ke Liu, Mao-Lan Li, Mao-Lan Li, Mao-Lan Li, Ya-Jun Geng, Ya-Jun Geng, Ya-Jun Geng, Ya-Jun Geng, Yang Yang, Yang Yang, Yang Yang, Yang Yang, Huai-Feng Li, Huai-Feng Li, Huai-Feng Li, Xue-Chuan Li, Xue-Chuan Li, Xue-Chuan Li, Xue-Chuan Li, Run-Fa Bao, Run-Fa Bao, Run-Fa Bao, Yi-Jun Shu, Yi-Jun Shu, Yi-Jun Shu, Hao Weng, Hao Weng, Hao Weng, Wei Gong, Wei Gong, Wei Gong, Wan Yee Lau, Xiang-Song Wu, Xiang-Song Wu, Xiang-Song Wu, Ying-Bin Liu, Ying-Bin Liu, Ying-Bin Liu, Ying-Bin Liu   +48 more
doaj   +1 more source

Infections Complicating Orthotopic Liver Transplantation: A Study Emphasizing Graft-Related Septicemia [PDF]

, 1976
In 93 recipients of 102 orthotopic liver homografts, the incidence of bacteremia or fungemia exceeded 70%. The graft itself was usually an entry site for systemic infection after both immunologic and nonimmunologic parenchymal injury, especially if there
Hansbrough, JF, Hoelscher, M, Porter, KA, Putnam, CW, Schröter, GPJ, Starzl, TE   +5 more
core   +1 more source

Evaluation of Combination Nivolumab and Ipilimumab Immunotherapy in Patients With Advanced Biliary Tract Cancers: Subgroup Analysis of a Phase 2 Nonrandomized Clinical Trial.

JAMA Oncology, 2020
Importance Biliary tract cancers represent a rare group of malignant conditions with very limited treatment options. Patients with advanced disease have a poor outcome with current therapies. Objective To evaluate the efficacy and safety of combination
O. Klein, D. Kee, A. Nagrial, B. Markman, C. Underhill, M. Michael, Louise Jackett, C. Lum, A. Behren, J. Palmer, N. Tebbutt, M. Carlino, J. Cebon   +12 more
semanticscholar   +1 more source

Updated management of malignant biliary tract tumors: an illustrative review [PDF]

, 2016
The management of malignant biliary tumors (MBTs) is complex and requires a multidisciplinary approach. Guidelines and methods of staging for biliary tumors have recently been released by main international societies, altering the clinical and radiologic
Cannavale, Alessandro, Catalano, Carlo, Fanelli, Fabrizio, Fiocca, Fausto, Gazzetti, Marianna, Maher, Ben, Santoni, Mariangela   +6 more
core   +1 more source

Chemotherapy for Biliary Tract Cancer in 2021

Journal of Clinical Medicine, 2021
Biliary tract cancer refers to a group of malignancies including cholangiocarcinoma, gallbladder cancer, and ampullary cancer. While surgical resection is considered the only curative treatment, postoperative recurrence can sometimes occur.
Takashi Sasaki, Tsuyoshi Takeda, T. Okamoto, M. Ozaka, N. Sasahira   +4 more
semanticscholar   +1 more source