Results 41 to 50 of about 159,964 (350)

Helicobacter pylori and Biliary Tract Cancers: A Meta-Analysis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2020
Background. Helicobacter pylori is detected in various extragastric diseases, including biliary tract cancers. Besides, gallbladder cancers, extracholangiocarcinomas, and intracholangiocarcinomas are highly lethal cancers with limited survival due to ...
Soumia Cherif, Kaoutar Bouriat, Hanane Rais, Said Elantri, Abdessamad Amine   +4 more
doaj   +1 more source

Single-cell atlas of diverse immune populations in the advanced biliary tract cancer microenvironment

npj Precision Oncology, 2022
Immunotherapies have been explored in treating solid tumors, albeit with disparate clinical effects in distinct cancer types. Systematic interrogation of immune cells in the tumor microenvironment (TME) is vital to the prediction of immunotherapy ...
Xuebing Shi, Zhixuan Li, Renqi Yao, Qingbao Cheng, Wei Li, Rui Wu, Zhihua Xie, Yanjing Zhu, Xinyao Qiu, Shuai Yang, Tao Zhou, Ji Hu, Yangqianwen Zhang, Tong Wu, Yan Zhao, Yani Zhang, Jianmin Wu, Hongyang Wang, Xiaoqing Jiang, Lei Chen   +19 more
doaj   +1 more source

The footprint of gut microbiota in gallbladder cancer: a mechanistic review

Frontiers in Cellular and Infection Microbiology
Gallbladder cancer (GBC) is the most common malignant tumor of the biliary system with the worst prognosis. Even after radical surgery, the majority of patients with GBC have difficulty achieving a clinical cure. The risk of tumor recurrence remains more
Shujie Liu, Weijian Li, Weijian Li, Weijian Li, Weijian Li, Jun Chen, Jun Chen, Jun Chen, Jun Chen, Maolan Li, Maolan Li, Maolan Li, Maolan Li, Yajun Geng, Yajun Geng, Yajun Geng, Yajun Geng, Yingbin Liu, Yingbin Liu, Yingbin Liu, Yingbin Liu, Wenguang Wu, Wenguang Wu, Wenguang Wu, Wenguang Wu   +24 more
doaj   +1 more source

A single‐arm, multicenter, open‐label phase 2 trial of surufatinib in patients with unresectable or metastatic biliary tract cancer

Cancer, 2021
Several clinical studies of vascular endothelial growth factor/vascular endothelial growth factor receptor (VEGF/VEGFR) therapy as a second‐line treatment for biliary tract cancer (BTC) have shown modest efficacy. In this study, surufatinib was evaluated
Jianming Xu, Y. Bai, Huichuan Sun, C. Bai, R. Jia, Yi Li, Wen-jie Zhang, Lei Liu, Cheng Huang, M. Guan, Jinghong Zhou, W. Su   +11 more
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Low expression of RACK1 is associated with metastasis and worse prognosis in cholangiocarcinoma

Heliyon
Background: Cholangiocarcinoma is a poorly prognostic malignant tumor, and the metastatic stage of cancer is not an early stage when diagnosed. Lymph node metastasis is common in the early stage.
Zhihui Gao, Wentao Sun, Xiaojian Ni, Wenze Wan, Tao Suo, Xiaoling Ni, Han Liu, Na Li, Sheng Shen, Houbao Liu   +9 more
doaj   +1 more source

Changing Landscape of Systemic Therapy in Biliary Tract Cancer

Cancers, 2022
Simple Summary Cancers from the bile ducts and gall bladder are lethal. Cure by surgery is not possible in most of these tumors as they are often identified in later stages. Unlike other cancers, they have few chemotherapy treatment options.
E. Woods, Dat Le, B. Jakka, A. Manne
semanticscholar   +1 more source

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

Arthritis Care &Research, EarlyView.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung, John P. Shelley, Gul Karakoc, John Still, Xiaodi Ruan, Jonathan Mosley, C. Michael Stein, Vivian K. Kawai   +7 more
wiley   +1 more source

Differential Item Functioning on the Patient Health Questionnaire‐8 by Disease Subtype, Language, Sex, and Age among People with Systemic Sclerosis: A Scleroderma Patient‐centered Intervention Network Cohort Study

Arthritis Care &Research, Accepted Article.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu, Marie‐Eve Carrier, Marie‐Claude Geoffroy, Meira Golberg, Linda Kwakkenbos, Susan J. Bartlett, Catherine Fortuné, Amy Gietzen, Karen Gottesman, Geneviève Guillot, Laura K. Hummers, Amanda Lawrie‐Jones, Vanessa L. Malcarne, Michelle Richard, Maureen Sauvé, Luc Mouthon, Andrea Benedetti, Brett D. Thombs, The SPIN Investigators, Claire E. Adams, Marie Hudson, Maureen D. Mayes, James Stempel, Robyn K. Wojeck, Christian Agard, Laurent Alric, Marc André, Floryan Beaslay, Elana J. Bernstein, Sabine Berthier, Lyne Bissonnette, Sophie Blaise, Eva Bories, Alessandra Bruns, Carlotta Cacciatore, Patricia Carreira, Marion Casadevall, Benjamin Chaigne, Lorinda Chung, Benjamin Crichi, Thylbert Deltombe, Christopher P. Denton, Tannvir Desroche, Robyn Domsic, James V. Dunne, Bertrand Dunogue, Regina Fare, Dominique Farge‐Bancel, Paul R. Fortin, Loraine Gauzère, Anne Gerber, Jessica K. Gordon, Brigitte Granel‐Rey, Aurélien Guffroy, Geneviève Gyger, Eric Hachulla, Daphna Harel, Monique Hinchcliff, Sabrina Hoa, Michael Hugues, Alena Ikic, Sindhu R. Johnson, Nader Khalidi, Kimberly S. Lakin, Marc Lambert, Maggie Larche, David Launay, Yvonne C. Lee, Paul Legendre, Catarina Leite, Hélène Maillard, Nancy Maltez, Joanne Manning, Isabelle Marie, Maria Martin Lopez, Thierry Martin, Ariel Masetto, Arsène Mekinian, Sheila Melchor Díaz, Morgane Mourguet, Christelle Nguyen, Karen Nielsen, Mandana Nikpour, Louis Olagne, Vincent Poindron, Janet Pope, Susanna Proudman, Grégory Pugnet, Loïc Raffray, François Rannou, Alexis Régent, Frederic Renou, Sébastien Rivière, David Robinson, Esther Rodríguez Almazar, Tatiana Sofia Rodríguez‐Reyna, Sophie Roux, Perrine Smets, Vincent Sobanski, Robert F. Spiera, Virginia Steen, Evelyn Sutton, Carter Thorne, Damien Vagner, John Varga, Pearce Wilcox, Vanessa Cook, Cassidy Dal Santo, Monica D'Onofrio, Elsa‐Lynn Nassar   +109 more
wiley   +1 more source

MicroRNA markers for the diagnosis of pancreatic and biliary-tract cancers.

PLoS ONE, 2015
It is difficult to detect pancreatic cancer or biliary-tract cancer at an early stage using current diagnostic technology. Utilizing microRNA (miRNA) markers that are stably present in peripheral blood, we aimed to identify pancreatic and biliary-tract ...
Motohiro Kojima, Hiroko Sudo, Junpei Kawauchi, Satoko Takizawa, Satoshi Kondou, Hitoshi Nobumasa, Atsushi Ochiai   +6 more
doaj   +1 more source