Results 71 to 80 of about 618 (230)

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

open access: yesMed Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang   +4 more
wiley   +1 more source

Regularized Joint Reconstruction and Slab Combination for Accelerated Three‐Dimensional Multi‐Slab Diffusion‐Weighted Imaging Using Multi‐Scale Energy Models

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To jointly reconstruct high‐resolution diffusion‐weighted volumes and eliminate slab‐boundary artifacts while preserving fine anatomical detail from undersampled 3D multi‐slab k‐space acquisitions. Methods A bilinear forward model was formulated to describe the 3D multi‐slab acquisition, treating the image volume and slab excitation ...
Reza Ghorbani   +4 more
wiley   +1 more source

R3Net: Recursive Residual Refinement Network Architecture for Decoder‐Free Medical Image Segmentation

open access: yesPrecision Radiation Oncology, EarlyView.
We propose R3Net, a decoder‐free medical image segmentation framework that recursively refines multiscale representations within the encoder using residual pathways. R3Net achieves competitive accuracy with reduced model complexity and improved computational efficiency across multiple medical imaging modalities.
Jing Huang   +5 more
wiley   +1 more source

New views of some invariants associated with the Cartesian 2D velocity gradient tensor

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Vorticity and divergence of horizontal flow are fundamental quantities in meteorology; both are linear functions of the four elements of the 2D velocity gradient tensor and both are formally unchanged under coordinate rotation. We explore four quadratic functions of the elements that are geometrically invariant in this sense, finding some novel ...
I. Roulstone, S. A. Clough, A. A. White
wiley   +1 more source

Evaluation of prestress losses in concrete beams using destructive and non‐destructive methods

open access: yesStructural Concrete, EarlyView.
Abstract Over the past few decades, prestressing techniques have become essential in the construction of key structures, infrastructure, and bridges. The serviceability and safety of prestressed concrete (PC) elements are closely tied to the effectiveness of the prestressing process.
A. N. Consiglio, G. Muciaccia, G. Rosati
wiley   +1 more source

Sensitivity study on accuracy and relevant parameters in numerical modeling of internal tendon breaks

open access: yesStructural Concrete, EarlyView.
Abstract This study investigates the numerical modeling of internal tendon breaks in prestressed concrete structures and evaluates the key parameters affecting accuracy. A combined approach is followed, involving global sensitivity analysis via the Elementary Effects Method and subsequent model calibration using experimental data from distributed fiber‐
Aeneas Paul, David Sanio, Peter Mark
wiley   +1 more source

Rotation capacity of continuous reinforced concrete slab strips revisited

open access: yesStructural Concrete, EarlyView.
Abstract Rotation capacity is a key characteristic of statically indeterminate reinforced concrete structures, as it (i) enables bending moment redistributions, whether intentionally introduced through optimized reinforcement layouts or arising from unforeseen self‐equilibrated stress states, and (ii) promotes large rotations at failure load, thereby ...
Nathalie Reckinger   +2 more
wiley   +1 more source

Experimental and analytical investigations on the effect of steel fibers on the crack behavior and strength of dapped‐end connections

open access: yesStructural Concrete, EarlyView.
Abstract Reinforced concrete (RC) dapped‐end connections feature a sharp re‐entrant corner subjected to high stress concentrations, leading to wide cracks under service loads and potential durability issues such as reinforcement corrosion. Effective crack control is therefore essential in the design of new dapped‐end connections. Steel fiber reinforced
Karin Yu   +3 more
wiley   +1 more source

Three‐parameter kinematic theory for shear assessment of reinforced concrete short columns

open access: yesStructural Concrete, EarlyView.
Abstract This work presents a rational kinematics‐based model for assessing the shear capacity of rectangular reinforced concrete short columns. Due to their high stiffness and brittleness, short columns are particularly vulnerable to seismic forces, often exhibiting critical failures.
Daniele Arcuri   +2 more
wiley   +1 more source

A literature‐based framework for anticipating golden jackal Canis aureus colonisation: insights from Europe and a Swiss case study

open access: yesWildlife Biology, EarlyView.
The expansion of the golden jackal Canis aureus in Europe, caused mainly by habitat fragmentation, climate change and the decline of large carnivores until half a century ago, poses emerging challenges for newly colonised regions. With the arrival of a new species, potential effects on local animal communities, hunting, livestock husbandry or the ...
Pablo del Rio   +3 more
wiley   +1 more source

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