Results 121 to 130 of about 282,772 (364)

Relationship between serum bilirubin levels and cardiovascular disease

open access: yesPLoS ONE, 2018
We tested the hypothesis that higher levels of bilirubin, a bile pigment with antioxidant properties, are associated with a decreased risk of cardiovascular disease (CVD).
S. Suh   +5 more
semanticscholar   +1 more source

Updated risk prediction model for pancreaticoduodenectomy using data from the National Clinical Database in Japan

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The calibration plots of the updated risk models for the endpoints were analyzed in each cohort. The predicted probability of each endpoint matched the observed probability in the development and validation cohorts. Abstract Aim Risk prediction models for mortality, severe postoperative complications, and postoperative pancreatic fistula in patients ...
Masamichi Mizuma   +8 more
wiley   +1 more source

Bilirubin-Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double-Strand Break Repair Pathways in Human Cells

open access: yesOxidative Medicine and Cellular Longevity, 2018
Unconjugated bilirubin is considered a potent antioxidant when present at moderate levels. However, at high concentrations, it produces severe neurological damage and death associated with kernicterus due to oxidative stress and other mechanisms.
Vipin Rawat   +4 more
semanticscholar   +1 more source

Effects of an increase in emergency cases with difficulties in transport to hospital during the COVID‐19 pandemic on postoperative short‐term outcomes of colorectal perforation: A study based on the National Clinical Database

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
In 2022, emergency cases with difficulties in transport markedly increased during the COVID‐19 pandemic, but had little effect on short‐term outcomes of colorectal perforation. These data suggest that the emergency system for patients with colorectal perforation was largely maintained during the pandemic in Japan, with no evidence indicating a serious ...
Shimpei Ogawa   +12 more
wiley   +1 more source

Beyond a Measure of Liver Function—Bilirubin Acts as a Potential Cardiovascular Protector in Chronic Kidney Disease Patients

open access: yesInternational Journal of Molecular Sciences, 2018
Bilirubin is a well-known neurotoxin in newborn infants; however, current evidence has shown that a higher serum bilirubin concentration in physiological ranges is associated with a lower risk for the development and progression of both chronic kidney ...
Ming-Tsun Tsai, D. Tarng
semanticscholar   +1 more source

Impact of hepatospleno volume ratio on postoperative chronic liver failure after major hepatectomy for perihilar cholangiocarcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The hepatospleno volume ratio and prealbumin levels 3 mo after major hepatectomy for perihilar cholangiocarcinoma are significant predictors of postoperative chronic liver failure (PCLF). The importance of this finding is that it emphasizes the need for targeted postoperative nutritional support and regular screening endoscopy to mitigate the risk of ...
Atsushi Takahashi   +8 more
wiley   +1 more source

Interpreting Missing Data Patterns in the ICU [PDF]

open access: yesarXiv, 2019
PURPOSE: Clinical examinations are performed on the basis of necessity. However, our decisions to investigate and document are influenced by various other factors, such as workload and preconceptions. Data missingness patterns may contain insights into conscious and unconscious norms of clinical practice.
arxiv  

Antioxidant bilirubin works in multiple ways to reduce risk for obesity and its health complications

open access: yesOpen Heart, 2018
Gilbert syndrome (GS) is a common genetic variant in which plasma unconjugated bilirubin levels are elevated throughout life, in the absence of hepatic pathology.1 This typically reflects decreased hepatic capacity for conjugation of bilirubin coupled ...
J. DiNicolantonio   +2 more
semanticscholar   +1 more source

FIB‐3 index as a novel age‐independent predictor of liver fibrosis and prognosis in hepatocellular carcinoma patients undergoing hepatectomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Fibrosis‐3 index (FIB‐3) can stratify the risk of the survival and the recurrence‐free survival. The FIB‐3 index is a reliable, age‐independent tool for assessing liver fibrosis and prognosis in HCC patients post‐hepatectomy. Its use may improve clinical outcomes and support personalized treatment strategies. Abstract Background Liver fibrosis is a key
Yuki Imaoka   +13 more
wiley   +1 more source

Morphology and composition of gallstones in 90 cholecystectomys performed at the Hospital Universitario del Caribe. 2008 -2009

open access: yesRevista Ciencias Biomédicas, 2010
The biliary lithiasis is a major problem in Western health systems; many studies have identified several risk factors including increased cholesterol saturation, which is why most of the gallstones can be dissolved with bile salts, but this constitutes a
Colpas-Morales Liceloth Sofía   +3 more
doaj  

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