Results 151 to 160 of about 282,772 (364)

Evaluation of therapeutic strategies of neonatal jaundice by medicinal herbalists of Mazandaran province: a descriptive cross sectional study

open access: yesJournal of Medicinal Plants, 2020
Background: Neonatal jaundice is as a disease caused by the abnormality of bilirubin metabolism that tendency of people to traditional medicine is very high for the treatment.
Moloud Fakhri   +6 more
doaj  

Assessment of ethnic differences in pharmacokinetics and clinical responses of acalabrutinib between Chinese and White patients with B‐cell malignancies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to assess differences between Chinese and White patients in pharmacokinetics (PK) of, and clinical response to, acalabrutinib and its pharmacologically active major metabolite, ACP‐5862, to support recommended dosing in Chinese patients with B‐cell malignancies.
Tingting Yao   +5 more
wiley   +1 more source

The protective effects of rutin on the liver, kidneys, and heart by counteracting organ toxicity caused by synthetic and natural compounds

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 39-56, January 2023., 2023
Rutin is a flavonoid present in many plant species. Because of its antioxidant, anti‐inflammatory, and anti‐apoptotic properties, rutin is of interest for its potential protective effects against toxic agents. Rutin has potential therapeutic effectiveness against several toxicants, and its beneficial effects are more than likely mediated by its ...
Sohrab Rahmani   +4 more
wiley   +1 more source

Association of serum bilirubin with longevity: Evidence from a retrospective longitudinal study and cross-sectional data

open access: yesAnthropological Review, 2017
Bilirubin is a potent antioxidant and an important anti-inflammatory factor. Therefore, there has been an increasing focus on serum bilirubin as a negative risk factor of cardiovascular mortality in men and an indicator of improved survival in both sexes,
Chmielewski Piotr   +4 more
doaj   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang   +7 more
wiley   +1 more source

Evaluation of the acute toxicity and 28‐days subacute toxicity of the alcoholic extract from Ganoderma leucocontextum

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 434-442, January 2023., 2023
The toxicity of Ganoderma leucocontextum was evaluated for the first time. No toxicological changes were found in acute and subacute toxicity test. Ganoderma leucocontextum showed a good safety profile in animal study. Abstract Ganoderma leucocontextum is a well‐known traditional medicine in Tibet Autonomous Region, which has benefits, such as anti ...
Shizhan Deng   +4 more
wiley   +1 more source

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy