Results 11 to 20 of about 282,772 (364)
Measurement and clinical usefulness of bilirubin in liver disease
Advances in Laboratory Medicine, 2021 Elevated plasma bilirubin levels are a frequent clinical finding. It can be secondary to alterations in any stage of its metabolism: (a) excess bilirubin production (i.e., pathologic hemolysis); (b) impaired liver uptake, with elevation of indirect ...
Guerra Ruiz Armando Raúl +7 more
doaj +2 more sources
Journal of Translational Medicine, 2022 Atherosclerosis is a chronic inflammatory disease caused mainly by lipid accumulation and excessive inflammatory immune response. Although the lipid-lowering and cardioprotective properties of bilirubin, as well as the negative relationship between ...
Guanmei Wen +4 more
semanticscholar +1 more source
Bilirubin as a Therapeutic Molecule: Challenges and Opportunities
Antioxidants, 2021 There is strong evidence that serum free bilirubin concentration has significant effects on morbidity and mortality in the most significant health conditions of our times, including cardiovascular disease, diabetes, and obesity/metabolic syndrome ...
C. Adin
semanticscholar +1 more source
Molecules, 2021 Recent work has shown that bilirubin has a hormonal function by binding to the peroxisome proliferator-activated receptor-α (PPARα), a nuclear receptor that drives the transcription of genes to control adiposity.
Darren M. Gordon +3 more
semanticscholar +1 more source
Bilirubin as a Metabolic Hormone: The Physiological Relevance of Low Levels.
American Journal of Physiology. Endocrinology and Metabolism, 2020 Recent research on bilirubin, a historically well-known waste product of heme catabolism, suggests an entirely new function as a metabolic hormone that drives gene transcription by nuclear receptors.
J. Creeden +3 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2021 Ectopic lipid accumulation in skeletal muscle and liver drives the pathogenesis of diabetes mellitus type 2 (DMT2). Mild hyperbilirubinaemia has been repeatedly suggested to play a role in the prevention of DMT2 and is known for its capacity to shape an ...
Claudia A. Hana +18 more
doaj +1 more source
Aquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 540-551, December 2022., 2022 Abstract Feed effectors have been suggested to improve the efficiency of plant‐based shrimp diets by increasing attractability and palatability. This research trial aimed to expand upon previous Pacific white shrimp (Litopenaeus vannamei) research involving plant‐based diets, feed effectors and passive acoustic monitoring (PAM) in a laboratory setting ...
Samuel Walsh +4 more
wiley +1 more source
Physiological Reviews, 2020 Bilirubin is the end product of heme catabolism formed during a process that involves oxidation-reduction reactions and conserves iron body stores. Unconjugated hyperbilirubinemia is common in newborn infants, but rare later in life. The basic physiology
T. Hansen, R. Wong, D. Stevenson
semanticscholar +1 more source
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 81-90, January 2023., 2023 XELOXIRI neoadjuvant chemotherapy appears to be feasible and efficacious for patients with LARC. Although neoadjuvant XELOXIRI alone did not yield our expected pCR rate, the local recurrence rate, 3‐year DFS and measures of safety met current standards.
Chu Matsuda +16 more
wiley +1 more source
External Drainage of Giant Infantile Choledochal Cyst before Definitive Repair: Is it Worth? [PDF]
Journal of Clinical and Diagnostic Research, 2017 Infantile Choledochal Cysts (IFCC) usually present with jaundice, acholic stool and abdominal lump or abdominal distension. If the surgical intervention is delayed, they rapidly progress to liver fibrosis which is considered to be irreversible if ...
Vijai Datta Upadhyaya +3 more
doaj +1 more source