Results 11 to 20 of about 299,762 (246)

Bilirubin as a Therapeutic Molecule: Challenges and Opportunities

Antioxidants, 2021
There is strong evidence that serum free bilirubin concentration has significant effects on morbidity and mortality in the most significant health conditions of our times, including cardiovascular disease, diabetes, and obesity/metabolic syndrome ...
C. Adin
semanticscholar   +1 more source

Gilbert’s Syndrome and the Gut Microbiota – Insights From the Case-Control BILIHEALTH Study

Frontiers in Cellular and Infection Microbiology, 2021
The heme catabolite bilirubin has anti-inflammatory, anti-oxidative and anti-mutagenic effects and its relation to colorectal cancer (CRC) risk is currently under evaluation.
Patrick A. Zöhrer, Patrick A. Zöhrer, Claudia A. Hana, Nazlisadat Seyed Khoei, Nazlisadat Seyed Khoei, Christine Mölzer, Marlies Hörmann-Wallner, Anela Tosevska, Anela Tosevska, Anela Tosevska, Daniel Doberer, Rodrig Marculescu, Andrew C. Bulmer, Craig W. Herbold, David Berry, David Berry, Karl-Heinz Wagner, Karl-Heinz Wagner   +17 more
doaj   +1 more source

Application of the ALBI Scoring System for Mortality Outcome Prediction in Patients with Hypertrophic Cardiomyopathy

Global Heart, 2022
Background: There is no information about the clinical significance of the albumin-bilirubin (ALBI) score in patients with hypertrophic cardiomyopathy (HCM).
Ping Qiao, Liying Li, Haiyan Ruan, Muxin Zhang, Ziqiong Wang, Xinran Li, Rufeng Shi, Xin Wei, Linjia Duan, Yi Zheng, Sen He   +10 more
doaj   +1 more source

Evaluation of simple antioxidant blood parameters in patients with migraine

Frontiers in Neurology, 2022
BackgroundThe study aims to investigate the role of serum albumin (ALB) and creatinine (CRE), bilirubin (BIL), and uric acid (UA) as major intravascular antioxidants in migraine.MethodsWe enrolled 148 patients with migraine and 150 age- and sex-matched ...
Zhenzhen Yang, Pengfei Xu, Chaofan Geng, Hongju Zhang   +3 more
doaj   +1 more source

Identification of Binding Regions of Bilirubin in the Ligand-Binding Pocket of the Peroxisome Proliferator-Activated Receptor-A (PPARalpha)

Molecules, 2021
Recent work has shown that bilirubin has a hormonal function by binding to the peroxisome proliferator-activated receptor-α (PPARα), a nuclear receptor that drives the transcription of genes to control adiposity.
Darren M. Gordon, Stephen H Hong, Z. Kipp, T. Hinds   +3 more
semanticscholar   +1 more source

Impact of Occupational Lead Exposure on Liver and Kidney Function Tests on Silver Jewellery Workers [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: In unorganised silver jewellery industry, lead fumes and lead oxide dusts are generated while manufacturing the silver ring and the workers involved in this business are highly exposed to lead.
Mandakini S Kshirsagar, Arun J Patil, Jyotsna A Patil   +2 more
doaj   +1 more source

Bilirubin as a Metabolic Hormone: The Physiological Relevance of Low Levels.

American Journal of Physiology. Endocrinology and Metabolism, 2020
Recent research on bilirubin, a historically well-known waste product of heme catabolism, suggests an entirely new function as a metabolic hormone that drives gene transcription by nuclear receptors.
J. Creeden, Darren M. Gordon, D. Stec, T. Hinds   +3 more
semanticscholar   +1 more source

Total bilirubin and fasting plasma glucose levels are associated with coronary collateral development in elderly patients [PDF]

Journal of Men's Health, 2021
Background and objective: We aimed to investigate biochemical factors affecting coronary collateral circulation development in an elderly population aged 75 years and over.
Ertan Vuruskan, Irfan Veysel Duzen, Mehmet Kaplan, Gokhan Altunbas, Enes Alıc, Fatma Yılmaz Coskun, Murat Sucu   +6 more
doaj   +1 more source

Prognostic Value of Transaminases and Bilirubin Levels at Admission to Hospital on Disease Progression and Mortality in Patients with COVID-19—An Observational Retrospective Study

Pathogens, 2022
Introduction: Given the impact of COVID-19 on the world healthcare system, and the efforts of the healthcare community to find prognostic factors for hospitalization, disease progression, and mortality, the aim of the present study was to investigate the
Antonio Russo, Mariantonietta Pisaturo, Roberta Palladino, Paolo Maggi, Fabio Giuliano Numis, Ivan Gentile, Vincenzo Sangiovanni, Vincenzo Esposito, Rodolfo Punzi, Giosuele Calabria, Carolina Rescigno, Angelo Salomone Megna, Alfonso Masullo, Elio Manzillo, Grazia Russo, Roberto Parrella, Giuseppina Dell’Aquila, Michele Gambardella, Antonio Ponticiello, Nicola Coppola, on behalf of CoviCam Group   +20 more
doaj   +1 more source

Molecular Physiology and Pathophysiology of Bilirubin Handling by the Blood, Liver, Intestine, and Brain in the Newborn.

Physiological Reviews, 2020
Bilirubin is the end product of heme catabolism formed during a process that involves oxidation-reduction reactions and conserves iron body stores. Unconjugated hyperbilirubinemia is common in newborn infants, but rare later in life. The basic physiology
T. Hansen, R. Wong, D. Stevenson
semanticscholar   +1 more source