Results 21 to 30 of about 109,357 (257)

Fetal and neonatal bilirubin metabolism

Frontiers in Pediatrics, 2023
Human fetal and neonatal bilirubin metabolism is centered on 4Z,15Z-bilirubin IXα (BR) due to the extremely low BR conjugating capacity of the liver. BR is a unique, highly lipophilic substance with physiological and toxic effects in the cell membranes ...
Susumu Itoh, Hitoshi Okada, Kosuke Koyano, Shinji Nakamura, Yukihiko Konishi, Takashi Iwase, Takashi Kusaka   +6 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Early prediction of adverse outcomes in infants with acute bilirubin encephalopathy. [PDF]

Ann Clin Transl Neurol, 2020
OBJECTIVE: Acute bilirubin encephalopathy (ABE) remains one of the important causes of neonatal mortality and child disability, early identification, and intervention which could improve outcomes.
Kang W, Yuan X, Zhang Y, Song J, Xu F, Liu D, Li R, Xu B, Li W, Cheng Y, Zhu C.   +10 more
europepmc   +2 more sources

Bile bilirubin pigment analysis in disorders of bilirubin metabolism in early infancy [PDF]

, 2001
BACKGROUNDEarly and accurate diagnosis of Crigler-Najjar syndrome, which causes prolonged unconjugated hyperbilirubinaemia in infancy, is important, as orthotopic liver transplantation is the definitive treatment.
M A Preece, McKiernan, P.J., Kelly, D.A., P J McKiernan, Kelly, Deirdre, B Burchell, Clarke, Douglas, Burchell, B, Lee, W. S., Beath, Susan, Baty, D, Clarke, D. J., Preece, M.A., Burchell, B., McKiernan, P. J., Lee, Way Seah, S V Beath, Clarke, DJ, D J Clarke, Clarke, D.J., Preece, Mary, Lee, WS, D Baty, W S Lee, Lee, W S, Beath, S.V., D A Kelly, Baty, D., Preece, M. A., Beath, S. V., McKiernan, Patrick, Kelly, D. A.   +31 more
core   +1 more source

Assessment of the Therapeutic Effect of Polyethylene glycol and Lactulose in Patients with Hepatic Encephalopathy

Novelty in Biomedicine, 2022
Background: The mechanism of cerebral dysfunction in hepatic encephalopathy is unknown, although ammonia produced by intestinal bacteria is an essential factor.
Majid Iranshahi Iranshahi, Parviz Amri, Mohamad Amri   +2 more
doaj   +1 more source

Fully automated simultaneous peripheral arteriovenous exchange transfusion not seen to aggravate brain function and the disorder of the internal environment in neonates with severe hyperbilirubinemia

Pediatrics and Neonatology, 2021
Background: The acute changes in brain function in newborn infants undergoing ET remain unclear. This study aimed to determine whether fully automated simultaneous peripheral arteriovenous ET would influence the brain function.
Wei-neng Lu, Xiao-yuan Yang, Shu-yao Ning, Zhuang-gui Chen, Si-nian Pan   +4 more
doaj   +1 more source

Bilirubin Induced Encephalopathy, a Review Article

, 2020
Hyperbilirubinemia is one of the most common neonatal disorders. Delayed diagnosis and treatment of the pathologic and progressive indirect hyperbilirubinemia lead to neurological deficits, defined as bilirubin induced encephalopathy .
Kazemian, Mohammad, Radfar, Mitra, Karimzadeh, Parvaneh, Fallahi, Minoo, Taslimi Taleghani, Naeeme, Nouripour, Shamsollah   +5 more
core   +1 more source

Risk factors for hepatic encephalopathy in patients with liver cirrhosis: a retrospective study

Di-san junyi daxue xuebao, 2019
Objective To explore the risk factors associated with hepatic encephalopathy in patients with cirrhosis. Methods A total of 188 cirrhotic patients diagnosed with hepatic encephalopathy admitted in our hospital during June 2016 and June 2018 were enrolled
WANG Na, LI Juan, LI Xia, LIANG Luwen, WANG Xiaomei   +4 more
doaj   +1 more source

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie [PDF]

, 2010
With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the need for improved methods of differential diagnosis. Exposure to bovine spongiform encephalopathy (
Bossers, A., A. Bossers, Y. Tang, Sauer, M., M. Sauer, L. J. M. van Keulen, J. P. M. Langeveld, J. G. Jacobs, Keulen, L.J.M., van, van Keulen, L.J.M., Tang, Y., Jacobs, J.G., Langeveld, J.P.M.   +12 more
core   +1 more source

A zebrafish model for studying the mechanisms of newborn hyperbilirubinemia and bilirubin-induced neurological damage

Frontiers in Cell and Developmental Biology, 2023
Unresolved neonatal hyperbilirubinemia may lead to the accumulation of excess bilirubin in the body, and bilirubin in neural tissues may induce toxicity. Bilirubin-induced neurological damage (BIND) can result in acute or chronic bilirubin encephalopathy,
Metehan Guzelkaya, Ebru Onal, Ebru Onal, Emine Gelinci, Abdullah Kumral, Abdullah Kumral, Gulcin Cakan-Akdogan, Gulcin Cakan-Akdogan   +7 more
doaj   +1 more source