Results 11 to 20 of about 20,671 (222)

A Self-Powered Biosensor for the Detection of Glutathione

open access: yesBiosensors, 2020
Glutathione is an important biological molecule which can be an indicator of numerous diseases. A method for self-powered detection of glutathione levels in solution has been developed using an enzymatic biofuel cell.
Brandon G. Roy   +4 more
doaj   +1 more source

The Role of Oxidative Stress in the Pathogenesis of Diabetic Vascular Complications [PDF]

open access: yesDiabetes & Metabolism Journal, 2012
Oxidative stress has been paid increasing attention to as an important causative factor for diabetic vascular complications. Among possible various sources, accumulating evidence has indicated that NAD(P)H oxidase may be the most important source for ...
Shuji Sasaki, Toyoshi Inoguchi
doaj   +1 more source

Electrochemical Sensor for Bilirubin Detection Using Paper-Based Screen-Printed Electrodes Functionalized with Silver Nanoparticles

open access: yesMicromachines, 2022
A notable diagnostic for the detection of hemolytic diseases is bilirubin, a by-product of haemoglobin breakdown. The concentration of bilirubin ranges from 0.3 to 1.9 mg in 100 mL of blood.
Nigar Anzar   +6 more
doaj   +1 more source

Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate

open access: yesFrontiers in Pharmacology, 2020
The inverse relationship of plasma bilirubin levels with liver fat accumulation has prompted the possibility of bilirubin as a therapeutic for non-alcoholic fatty liver disease. Here, we used diet-induced obese mice with non-alcoholic fatty liver disease
Terry D. Hinds   +5 more
doaj   +1 more source

Determination of the Sum of Bilirubin Sugar Conjugates in Plasma by Bilirubin Oxidase [PDF]

open access: yesClinical Chemistry, 1999
Abstract Background: A reliable indicator of cholestasis is the presence of abnormal concentrations of bilirubin mono- and diglucuronide [conjugated bilirubin (CB)] in blood. A routine assay of CB is available only to those who possess a certain type of clinical analyzer. We describe a two-point manual method for CB that could be adapted
B T, Doumas   +4 more
openaire   +2 more sources

Operational impact of using a vanadate oxidase method for direct bilirubin measurements at an academic medical center clinical laboratory

open access: yesPractical Laboratory Medicine, 2017
Objectives: The aim of this study was to compare the operational impact of using vanadate oxidase versus diazo direct bilirubin assays for an academic medical center patient population.
Neha Dhungana   +2 more
doaj   +1 more source

Electricity production from palm oil mill effluent (POME) through the integration of a microbial fuel cell and bilirubin oxidase-producing bacteria

open access: yesJournal of Degraded and Mining Lands Management, 2023
The microbial fuel cell (MFC) is a device that harnesses microbial metabolism to convert chemical energy into bio-electrical energy. Extensive research has demonstrated its efficacy in both wastewater treatment and power generation applications.
Junjira Thipraksa   +2 more
doaj   +1 more source

Simulation of Bilirubin Detoxification in the Newborn Using an Extracorporeal Bilirubin Oxidase Reactor [PDF]

open access: yesPediatric Research, 1989
Jaundice, which is characterized by an excessive accumulation of bilirubin in the blood and tissues, occurs in 13% of newborns. The common treatments for neonatal jaundice are phototherapy and blood exchange transfusion. A novel approach using an extracorporeal blood filter containing immobilized bilirubin oxidase was recently proposed to detoxify ...
C J, Mullon, C M, Tosone, R, Langer
openaire   +2 more sources

Bilirubin inhibits the up-regulation of inducible nitric oxide synthase by scavenging reactive oxygen species generated by the toll-like receptor 4-dependent activation of NADPH oxidase

open access: yesRedox Biology, 2015
It has been previously shown that bilirubin prevents the up-regulation of inducible nitric oxide synthase (iNOS) in response to LPS. The present study examines whether this effect is exerted through modulation of Toll-Like Receptor-4 (TLR4) signaling ...
Gila Idelman   +2 more
doaj   +1 more source

Translational Approach to the Protective Effect of Bilirubin in Diabetic Kidney Disease

open access: yesBiomedicines, 2022
Bilirubin has been regarded as a powerful endogenous antioxidant and anti-inflammatory molecule, able to act on cellular pathways as a hormone. Diabetic kidney disease (DKD) is a common chronic complication of diabetes, and it is the leading cause of end-
Annalisa Bianco   +2 more
doaj   +1 more source

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