Results 101 to 110 of about 183 (125)

The specificity of biliverdin reductase. The reduction of biliverdin XIII isomers.

Biochimica et biophysica acta, 1984
The substrate specificity of the different molecular forms of biliverdin reductase (bilirubin:NAD(P)+ oxidoreductase, EC 1.3.1.24) using biliverdin XIII alpha, XIII beta and XIII gamma was examined. It was found that molecular form 1 (the major form in normal rat liver) reduced biliverdin XIII alpha at a much higher rate than the other two isomers ...
J, Awruch, M L, Tomaro, R B, Frydman, B, Frydman   +3 more
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Confirmation of the assignment of human biliverdin reductase to chromosome 7

Annals of Human Genetics, 1984
SummarySegregation of biliverdin reductase (BLVR) in 11 independent human‐mouse hybrids confirms the assignment to chromosome 7 in man and gives a regional localization of 7pter → 7q22. Isoelectric focusing of BLVR reveals genetically determined variation among inbred strains of mice.
M, Parkar, S J, Jeremiah, S, Povey, A F, Lee, F O, Finlay, P N, Goodfellow, E, Solomon   +6 more
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Biliverdin reductase activity in cattle, sheep, rabbits and rats

International Journal of Biochemistry, 1989
1. Biliverdin reductase (BVR) activity was measured in post-microsomal supernatants of livers of cattle, sheep, rabbits and rats. BVR activities in bovine and ovine livers were 4.7 and 5.0%, respectively, of rat liver activity. 2. The finding of BVR activity in ruminants is in contrast to a previous report and may be due to the use of a different assay
J W, George, K, Nulk, A, Weiss, M L, Bruss, C E, Cornelius   +4 more
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Evidences of Biological Functions of Biliverdin Reductase A in the Bovine Epididymis

Journal of Cellular Physiology, 2015
Epididymal sperm binding protein 1 (ELSPBP1) is secreted by the epididymal epithelium via epididymosomes and is specifically transferred to dead spermatozoa during epididymal transit. We identified biliverdin reductase A (BLVRA) as a partner of ELSPBP1 by immunoprecipitation followed by tandem mass spectrometry.
Olivier, D'Amours, Gilles, Frenette, Patrick, Caron, Clémence, Belleannée, Chantal, Guillemette, Robert, Sullivan   +5 more
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Affinity Chromatography of Biliverdin Reductase

Biochemical Society Transactions, 1976
WATT, JANE, O'CARRA, PÁDRAIG
openaire   +2 more sources

Crystal structure of rat biliverdin reductase.

Nature structural biology, 2001
Biliverdin reductase (BVR) is a soluble cytoplasmic enzyme that catalyzes the conversion of biliverdin to bilirubin using NADH or NADPH as electron donor. Bilirubin is a significant biological antioxidant, but it is also neurotoxic and the cause of kernicterus. In this study, we have determined the crystal structure of rat BVR at 1.4 A resolution.
A, Kikuchi, S Y, Park, H, Miyatake, D, Sun, M, Sato, T, Yoshida, Y, Shiro   +6 more
openaire   +1 more source

The heme oxygenase/biliverdin reductase system in skin cancers.

Journal of biological regulators and homeostatic agents, 2015
The heme oxygenase/biliverdin reductase (HO/BVR) pathway enhances cell stress response by degrading excess heme or producing antioxidant and cytoprotective molecules. Recently, members of the HO/BVR system have been proposed as biomarkers for the early diagnosis of free radical-related diseases.
Arena, Vincenzo, Pennacchia, Ilaria, Guerriero, Giuseppe, Mancuso, Cesare   +3 more
openaire   +2 more sources

Biliverdin reductase activity in relation to bilirubin

Biochemical Society Transactions, 1992
R, Beri, R, Chandra
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Biliverdin reductase

1993
Dietmar Schomburg, Margit Salzmann, Dörte Stephan   +2 more
openaire   +1 more source

Biliverdin Reductase A is a major determinant of neuroprotective Nrf2 signaling

Abstract Biliverdin reductase A (BVRA), the terminal enzyme in heme catabolism, generates the neuroprotective and lipophilic antioxidant bilirubin. Here, we identify a novel non-enzymatic role for BVRA in redox regulation. We show that BVRA directly interacts with nuclear factor erythroid-derived factor-like 2 (Nrf2), the master ...
Chirag, Vasavda, Ruchita, Kothari, Navneet Ammal, Kaidery, Suwarna, Chakraborty, Sunil Jamuna, Tripathi, Ryan S, Dhindsa, Samaneh, Saberi, Julia E, Lefler, Priyanka, Kothari, Kalyani, Chaubey, Cristina, Ricco, Adele M, Snowman, Michael C, Ostrowski, Eugenio, Barone, Lakshminarayan M, Iyer, L, Aravind, Sudarshana M, Sharma, Andrew A, Pieper, Bobby, Thomas, Solomon H, Snyder, Bindu D, Paul   +20 more
openaire   +2 more sources