Results 91 to 100 of about 107,951 (150)

Data from: Immune challenges decrease biliverdin concentration in the spleen of Northern Bobwhite Quail, Colinus virginianus

, 2018
Most antioxidants have multiple functions; in addition to minimizing oxidative damage, many antioxidants have immune-modulating properties. For example, biliverdin is produced in the liver and spleen from the breakdown of heme, and has putative immune ...
Butler, Michael W., Hines, Justin K., Homsher, Melissa P., Astor, Michael T.   +3 more
core   +1 more source

The impact of ribavirin-induced anemia on BLVRA expression.

, 2013
BLVRA, biliverdin reductase A; HB, hemoglobin.
Tomas Zima (388035), Kristyna Kubickova (388033), Hendrik J. Vreman (388031), Petr Urbanek (388036), Miluse Kreidlova (388034), Martin Lenicek (355728), Ondrej Luksan (388032), Lucie Muchova (388030), Libor Vitek (355729), Iva Subhanova (388029)   +9 more
core   +1 more source

An Alternative to Biliverdin, Mesobiliverdin IXα and Mesobiliverdin-Enriched Microalgae: A Review on the Production and Applications of Mesobiliverdin-Related Products

Molecules
Despite attracting interest for decades due to its anti-inflammatory and antioxidant capabilities, the use of biliverdin IXα (BV) in medicine and agriculture is hampered by uncertain purity and limited availability.
Naveena Poudyal, Jon Y. Takemoto, Yuan-Yu Lin, Cheng-Wei T. Chang   +3 more
doaj   +1 more source

Nuclear localization of biliverdin reductase in the rat kidney: response to nephrotoxins that induce heme oxygenase-1.

, 2001
Biliverdin reductase catalyzes the reduction of biliverdin, the product of heme oxygenase (HO) activity, to bilirubin. The reductase is unique among all enzymes characterized to date in being dual pH/cofactor-dependent.
Tian J Huang, Nariman Panahian, James F Ewing, Mahin D Maines   +3 more
core  

Heme oxygenase-1, heme oxygenase-2 and biliverdin reductase in peripheral ganglia from rat, expression and plasticity

, 1999
The expression of inducible and constitutive heme oxygenase and biliverdin reductase was studied in normal and cultured peripheral ganglia from adult rats, using immunocytochemistry and in situ hybridization.
E. Elmér, M. Kanje, S. Magnusson, Magnusson, S, Ekstrom, J, P. Alm, J. Ekström, L. Ny, Elmer, Eskil, Kanje, Martin, Alm, Per, Ny, L, Alm, Per,, Elmer, Eskil,, Lund University.   +14 more
core   +1 more source

Biliverdin Reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β

Redox Biology
Brain insulin resistance links the failure of energy metabolism with cognitive decline in both type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular changes preceding overt brain insulin resistance remain unexplored ...
Chiara Lanzillotta, Antonella Tramutola, Simona Lanzillotta, Viviana Greco, Sara Pagnotta, Caterina Sanchini, Silvia Di Angelantonio, Elena Forte, Serena Rinaldo, Alessio Paone, Francesca Cutruzzolà, Flavia Agata Cimini, Ilaria Barchetta, Maria Gisella Cavallo, Andrea Urbani, D. Allan Butterfield, Fabio Di Domenico, Bindu D. Paul, Marzia Perluigi, Joao M.N. Duarte, Eugenio Barone   +20 more
doaj   +1 more source

Biliverdin reductase-A is a key modulator in insulin signaling and metabolism

Trends in Endocrinology & Metabolism
Biliverdin reductase-A (BVRA) is a pleiotropic enzyme traditionally known for its antioxidant role in the heme degradation pathway. Recent findings have redefined BVRA as a master regulator of insulin signaling, acting as a kinase, scaffold, and redox-sensitive integrator of metabolic cues.
Tramutola, Antonella, Di Domenico, Fabio, Perluigi, Marzia, Barone, Eugenio   +3 more
openaire   +3 more sources

Heme catabolic pathway.

, 2013
Heme oxygenase, the rate limiting enzyme in the heme catabolic pathway, catalyzes oxidative degradation of heme to form equimolar amounts of bioactive products carbon monoxide, iron and biliverdin, which is subsequently reduced to bilirubin by biliverdin
Tomas Zima (388035), Kristyna Kubickova (388033), Hendrik J. Vreman (388031), Petr Urbanek (388036), Miluse Kreidlova (388034), Martin Lenicek (355728), Ondrej Luksan (388032), Lucie Muchova (388030), Libor Vitek (355729), Iva Subhanova (388029)   +9 more
core   +1 more source

Bilirubin and the Yellow Players in Ferroptosis: A Delicate Balance in Human Health and Disease, with a Focus on the Liver, Cardiovascular System, and Brain

Biomolecules
Ferroptosis is a unique form of regulated lytic cell death driven by intracellular iron overload, excessive production of reactive oxygen species, failure of antioxidant defense systems, lipid peroxidation, and subsequent plasma membrane damage.
Camilla Dalla Verde, Libor Vitek, Claudio Tiribelli, Silvia Gazzin   +3 more
doaj   +1 more source

Tumor-Draining Lymph Secretome En Route to the Regional Lymph Node in Breast Cancer Metastasis

Breast Cancer: Targets and Therapy, 2020
Sulma I Mohammed,1,2 Odalys Torres-Luquis,1 Weidong Zhou,3 Nadia Attalah Lanman,1,2 Virginia Espina,3 Lance Liotta3 1Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, USA; 2Purdue University Center for Cancer Research ...
Mohammed SI, Torres-Luquis O, Zhou W, Lanman NA, Espina V, Liotta L   +5 more
doaj