Results 71 to 80 of about 107,951 (150)

INHIBITION OF BILIVERDIN REDUCTASE DIMINISHED THE PROTECTIVE ACTIVITY OF BILIRUBIN AND BILIVERDIN AGAINST OXIDATIVE STRESS-INDUCED INJURY IN HUMAN VASCULAR ENDOTHELIUM

Acta Chimica Slovenica
Endothelial dysfunction, a key factor in cardiovascular diseases, is further aggravated by oxidative stress. Biliverdin (BV) and bilirubin (BR) are potent antioxidants that protect endothelial cells, with biliverdin reductase (BVR) converting BV to BR ...
Kuldeepak Sharma, Irena Zajc, Alen Albreht, Lovro Ziberna   +3 more
doaj   +1 more source

Isolation of blue-green eggshell pigmentation-related genes from Putian duck through RNA-seq

BMC Genomics, 2019
Background The diversity of avian eggshell colour plays important biological roles in ensuring successful reproduction. Eggshell colour is also an important trait in poultry, but the mechanisms underlying it are poorly understood in ducks.
Ding-Ping Bai, Xin-Yu Lin, Yan Wu, Shi-Ye Zhou, Zhong-bin Huang, Yi-Fan Huang, Ang Li, Xiao-Hong Huang   +7 more
doaj   +1 more source

Phycocyanobilin biosynthesis in Galdieria sulphuraria requires isomerization of phycoerythrobilin synthesized by bilin reductases

The FEBS Journal, Volume 293, Issue 10, Page 2908-2927, May 2026.
The biosynthesis of bilins, tetrapyrroles essential for light harvesting and sensing, is performed by specific enzymes (FDBRs). In Galdieria sulphuraria, both phycobiliprotein types bind phycocyanobilin, despite lacking the canonical synthesizing gene PCYA. Instead, PEBA and PEBB are encoded, producing phycoerythrobilin, proposed to be later isomerized
Federica Frascogna, Nathan C. Rockwell, Jana Hartmann, Julie M. Mudler, Nicole Frankenberg‐Dinkel   +4 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Biliverdin-IX alpha reductase and biliverdin-IX beta reductase from human liver. Purification and characterization.

Journal of Biological Chemistry, 1994
This report describes for the first time the identification of four forms of biliverdin reductase including two biliverdin-IX beta reductases and two biliverdin-IX alpha reductases, designated isozymes I and II and isozymes III and IV, respectively, in human liver cytosolic fractions. The four forms of biliverdin reductase were purified to homogeneity.
T, Yamaguchi, Y, Komoda, H, Nakajima
openaire   +2 more sources

Ferroptotic neurodegeneration and diet: a narrative review

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Dietary regimes and separate components have been reported to reduce ferroptosis by (1) altering iron metabolism, (2) increasing antioxidant defense, and (3) reducing lipid peroxidation. This ultimately leads to reduced ferroptosis and neurodegeneration.
Ximaine R. van der Burg, Danielle V. Toen, Scott Ayton, Hanno Pijl, Louise van der Weerd   +4 more
wiley   +1 more source

Biliverdin reductase-induced phytochrome chromophore deficiency in transgenic tobacco [PDF]

, 2001
Targeted expression of mammalian biliverdin IXalpha reductase (BVR), an enzyme that metabolically inactivates linear tetrapyrrole precursors of the phytochrome chromophore, was used to examine the physiological functions of phytochromes in the ...
Brian Thomas, Keara A. Franklin, Stephen D. Jackson, Lagarias, J. Clark, Marc W. Crepeau, Franklin, Keara A., Montgomery, Beronda L., Terry, Matthew J., Beronda L. Montgomery, Crepeau, Marc W., Jackson, Stephen D., Matthew J. Terry, Thomas, Brian, J. Clark Lagarias   +13 more
core   +2 more sources

The Crosstalk Mechanisms Between Ferroptosis and Pyroptosis and Their Applications in Diseases: From Molecular Networks to Clinical Strategies

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Ferroptosis and pyroptosis are two distinct forms of regulated cell death that play crucial roles in cancer, neurodegeneration, and inflammatory diseases. Ferroptosis is characterised by iron‐dependent lipid peroxidation, while pyroptosis is an inflammatory cell death mediated by gasdermin proteins.
Wei‐Yi Zhao, Lu‐yao Li, Fang‐wang Ye, Jin‐Wei Zhao   +3 more
wiley   +1 more source

Kinetic studies on biliverdin-IXalpha reductase

, 2006
THESIS 7990The species distribution of biliverdin-IXa reductase (BVR-A) has been reinvestigated. It appears increasingly likely that birds and amphibia have the potential to express an active biliverdin-IXa reductase. The full length cDNAs encoding human,
Franklin, Edward
core  

Urobilin Derived from Bilirubin Bioconversion Binds Albumin and May Interfere with Bilirubin Interacting with Albumin: Implications for Disease Pathology

Biomedicines
Background/Objectives: Bilirubin is a hydrophobic molecule that binds the carrier protein albumin for transport through systemic circulation. Bilirubin is cleared from the body through the liver and excreted into the intestines, where the microbiota ...
Kevin I. Williams, Priyanka Suryadevara, Chang-Guo Zhan, Terry D. Hinds, Zachary A. Kipp   +4 more
doaj   +1 more source