Results 71 to 80 of about 183 (125)

Biliverdin Reductase A (BLVRA) Promotes Colorectal Cancer Cell Progression by Activating the Wnt/β-Catenin Signaling Pathway

open access: yesCancer Management and Research, 2020
Haiyan Mao,1,2 Yuan Xu,1 Zhengrong Zhang,1 Guozhuang Sun,3 Zhu Wang,1 Dawei Qiao,2 Xudong Yin,1 Siping Liu,4 Ping Bo2 1Oncology Department, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu Province 225000, People ...
Mao H   +8 more
doaj  

Bilirubin: an endogenous molecule with antiviral activity in vitro.

open access: yesFrontiers in Pharmacology, 2012
Bilirubin-IX-alpha (BR) is the final product of heme metabolism through the heme oxygenase/biliverdin reductase (HO/BVR) system. Previous papers reported on the microbicidal effects of the HO by-products biliverdin-IX-alpha, carbon monoxide and iron ...
Rosaria eSantangelo   +5 more
doaj   +1 more source

The role of bilirubin in diabetes, metabolic syndrome, and cardiovascular diseases

open access: yesFrontiers in Pharmacology, 2012
Bilirubin belongs to a phylogenetically old superfamily of tetrapyrrolic compounds, which have multiple biological functions. Although for decades they were believed to be only a waste product of the heme catabolic pathway at best, and a potentially ...
Libor eVitek
doaj   +1 more source

Epididymosomes: a heterogeneous population of microvesicles with multiple functions in sperm maturation and storage

open access: yesAsian Journal of Andrology, 2015
Extracellular microvesicles present in the epididymal fluid have been named epididymosomes. Many epididymosome-associated proteins are transferred to spermatozoa during their maturation in the excurrent duct.
Robert Sullivan
doaj   +1 more source

An Alternative to Biliverdin, Mesobiliverdin IXα and Mesobiliverdin-Enriched Microalgae: A Review on the Production and Applications of Mesobiliverdin-Related Products

open access: yesMolecules
Despite attracting interest for decades due to its anti-inflammatory and antioxidant capabilities, the use of biliverdin IXα (BV) in medicine and agriculture is hampered by uncertain purity and limited availability.
Naveena Poudyal   +3 more
doaj   +1 more source

Biliverdin Reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β

open access: yesRedox Biology
Brain insulin resistance links the failure of energy metabolism with cognitive decline in both type 2 Diabetes Mellitus (T2D) and Alzheimer's disease (AD), although the molecular changes preceding overt brain insulin resistance remain unexplored ...
Chiara Lanzillotta   +20 more
doaj   +1 more source

The Heme Oxygenase/Biliverdin Reductase System and Its Genetic Variants in Physiology and Diseases

open access: yesAntioxidants
Heme oxygenase (HO) metabolizes heme into ferrous iron, carbon monoxide (CO), and biliverdin-IXα (BV), the latter being reduced into bilirubin-IXα (BR) by the biliverdin reductase-A (BVR).
Cesare Mancuso
doaj   +1 more source

Tumor-Draining Lymph Secretome En Route to the Regional Lymph Node in Breast Cancer Metastasis

open access: yesBreast Cancer: Targets and Therapy, 2020
Sulma I Mohammed,1,2 Odalys Torres-Luquis,1 Weidong Zhou,3 Nadia Attalah Lanman,1,2 Virginia Espina,3 Lance Liotta3 1Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, USA; 2Purdue University Center for Cancer Research ...
Mohammed SI   +5 more
doaj  

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