African Research Journal of Biosciences, 2023 This study delves into the therapeutic potential of two natural compounds, Amentoflavone and Bilobetin, by investigating their interactions with the BPIFB4 protein. BPIFB4, a member of the BPI fold-containing superfamily, has been associated with various biological processes, particularly in longevity and cardioprotection( LAV-BPIFB4).
openaire +1 more source
Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies [PDF]
, 2023 Objectives: This scoping review aims to present flavonoid compounds' promising effects and possible mechanisms of action on potential therapeutic targets in the SARS-CoV-2 infection process.
Araujo, DCD +11 more
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Inhibitory Potency of Amentoflavone and Bilobetin on the Binding of Androstenedione to Aromatase in HR+ Breast Cancer of Postmenopausal Women: An In Silico Approach [PDF]
BIO Web of ConferencesAndrostenedione (ASD) is a natural substrate of the aromatase enzyme in synthesizing estrone, a primary form of estrogen in postmenopausal women. Aromatase inhibition can be a promising strategy in treating hormone receptor-positive (HR+) breast cancer ...
Pinanti Honesty N.
doaj +1 more source
Natural products targeting ferroptosis in cancer: molecular mechanisms and applications. [PDF]
Front OncolFerroptosis is a novel class of programmed cell death that is mainly dependent on intracellular iron accumulation and lipid peroxidation. Ferroptosis is closely related to a variety of human diseases, especially different kinds of cancer.
Ye X, Ju X.
europepmc +3 more sources
Investigations on the chemical composition of volatile oils extracted from the leaves of spontaneous and cultivated Taxus baccata L. trees [PDF]
, 2023 Taxus L. is accepted in the literature as natural resources of biologically active compounds and volatile oils, with applications in medicine, pharmaceuticals, food, cosmetics, and with ecological impact on the natural living environment. In this context,
BĂDULESCU, Liliana +6 more
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Anticancer Effects of Five Biflavonoids from Ginkgo Biloba L. Male Flowers In Vitro
Molecules, 2019 Ginkgo biloba L., an ancient dioecious gymnosperm, is now cultivated worldwide for landscaping and medical purposes. A novel biflavonoid—amentoflavone 7′′-O-β-d-glucopyranoside (1)—and four known biflavonoids were isolated ...
Min Li +7 more
doaj +1 more source
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds [PDF]
, 2016 Misfolding and aggregation of the transthyretin (TTR) protein leads to certain forms of amyloidosis. Some nutraceuticals, such as flavonoids and natural polyphenols, have recently been investigated as modulators of the self-assembly process of TTR, but ...
BRACA, ALESSANDRA +6 more
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Journal of Cellular and Molecular Medicine, Volume 24, Issue 20, Page 11922-11935, October 2020., 2020 Abstract Selaginella moellendorffii Hieron. (SM), a perennial evergreen plant, has been used in the treatment of acute infectious hepatitis, thoracic and hypochondriac lumbar contusions, systemic oedema and thrombocytopaenia. However, the role of a biflavonoid‐rich extract from SM (SM‐BFRE) in anti‐larynx cancer has rarely been reported. In this study,
Huiqi Huang +8 more
wiley +1 more source
Phytochemical and Ethno-Pharmacological Review of the Genus Araucaria – Review [PDF]
, 2013 Distribution, traditional uses, isolated chemical constituents and pharmacological activities of some common species of the genus Araucaria are reviewed in this paper. Almost 19 species belong to the genus, Araucaria.
Aslam, MS +3 more
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Edible Flowers: Antioxidant Compounds and Their Functional Properties [PDF]
, 2021 Edible flowers have been widely consumed for ages until now. The attractive colors and shapes, exotic aroma, and delightful taste make edible flowers very easy to attain.
Oktavirina, Viki +3 more
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