Results 21 to 30 of about 451 (138)

Natural and Nature-Derived Products Targeting Human Coronaviruses [PDF]

, 2021
The ongoing pandemic of severe acute respiratory syndrome (SARS), caused by the SARS-CoV-2 human coronavirus (HCoV), has brought the international scientific community before a state of emergency that needs to be addressed with intensive research for the
Alexis, Michael N., Corona, Angela, Skaltsounis, Alexios-Leandros, Tramontano, Enzo, Vougogiannopoulou, Konstantina   +4 more
core   +1 more source

Paclitaxel‐Containing Extract Exerts Anti‐Cancer Activity through Oral Administration in A549‐Xenografted BALB/C Nude Mice: Synergistic Effect between Paclitaxel and Flavonoids or Lignoids

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Taxus yunnanensis is a paclitaxel‐containing herb with traditional usage in cancer treatment, and its extract possesses great oral bioavailability of paclitaxel. However, it is elusive whether paclitaxel‐containing extract (HDS‐1) can exert anti‐tumor effect through oral administration and how other components contribute to its efficacy.
Dake Cai, Jing Jin, Huichang Bi, Guoping Zhong, Minhua Zhou, Jianfen Guo, Yike Cai, Miaoyin Liang, Qiong Gu, Zixuan Hu, Yijing Lai, Zi Dai, Lingjie Li, Yuxing Chen, Haili Gao, Min Huang, Nianping Feng   +16 more
wiley   +1 more source

Virtual Screening of Natural Compounds Against Six Protein Receptors Coded by The SARS-CoV-2 Genome [PDF]

, 2023
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the virus that causes Coronavirus 2019 (COVID-19). To date, there has been no proven effective drug for the treatment or prevention of COVID-19.
Awaluddin, Fikry, Batubara, Irmanida, Tri Wahyudi, Setyanto   +2 more
core   +2 more sources

Ginkgo biloba: A Treasure of Functional Phytochemicals with Multimedicinal Applications

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Ginkgo biloba is an ancient plant species that is thought to provide a variety of health benefits to living organisms and contains plenty of bioactive components, making it a chemically diversified plant. G. biloba has been shown to have a variety of medicinal and pharmacological properties, including anticancer, antidementia, antidiabetic, antiobesity,
Noor-E-Tabassum, Rajib Das, Mashia Subha Lami, Arka Jyoti Chakraborty, Saikat Mitra, Trina Ekawati Tallei, Rinaldi Idroes, Amany Abdel-Rahman Mohamed, Md. Jamal Hossain, Kuldeep Dhama, Gomaa Mostafa-Hedeab, Talha Bin Emran, Harquin Simplice Foyet   +12 more
wiley   +1 more source

Development and Characterization of Potato Starch-Pectin-Based Active Films Enriched With Juniper Berry Essential Oil for Food Packaging Applications. [PDF]

Food Sci Nutr
Significant antibacterial activity of the bioactive films was observed against P. aeruginosa, S. aureus, and C. albicans. These findings suggest that JBEO enhances the functional and active properties of PSP edible films, making them suitable for food packaging applications.
Bhatia S, Jawad M, Chinnam S, Al-Harrasi A, Shah YA, Khan TS, Al-Azri MS, Koca E, Aydemir LY, Dıblan S, Mohan S, Najmi A, Khalid A, Khan MR.   +13 more
europepmc   +2 more sources

Bilobetin, a novel small molecule inhibitor targeting influenza virus polymerase acidic (PA) endonuclease was screened from plant extracts

Natural Product Research, 2020
The influenza A virus polymerase acidic (PA) endonuclease is an attractive target for anti-influenza drug development. In this study, plant extracts were used to screen the inhibitor against the PA endonuclease and its mutant. In 45 kinds of plant extracts, eight can effectively inhibit the PAN and PAN–I38T mutant in the primary screening.
Jinrui, Zhang, Ye, Wang
openaire   +2 more sources

Fertility booster effect of Selaginella bryopteris (Sanjivani) against high dose of estradiol exposed Swiss Albino mice [PDF]

, 2022
The present investigation was aimed to examine the antifertility effects of estradiol and phytochemical influences of Selaginella bryopteris (Sanjivani) in Swiss albino mice.
Abhinav Srivastava, Arun Kumar, Kritika Singh, Pankaj Kumar, Prabhat Shankar, Priti Mathur   +5 more
core   +2 more sources

In silico molecular docking and ADMET prediction of Ginkgo biloba biflavonoids as dual inhibitors of human HMG-CoA reductase and α-amylase [PDF]

Journal of the Serbian Chemical Society
There is an increasing interest in investigating phytochemicals as inhibitors of HMG-CoA reductase (HMGR) and α-amylase enzymes. Inhibition of these enzymes helps manage hypercholesterolemia and diabetes by reducing cholesterol synthesis and blood sugar ...
Agosto Nesteve John B.
doaj   +1 more source

Computer-assisted evaluation of plant-derived β-secretase inhibitors in Alzheimer’s disease

Egyptian Journal of Medical Human Genetics, 2021
Background Alzheimer’s disease (AD) is a progressive neurodegenerative age-related dementia that results in memory loss of elderly people. Many hypotheses have been formally articulated till now to decipher the pathogenesis of this disease.
Md. Asad Ullah, Fatema Tuz Johora, Bishajit Sarkar, Yusha Araf, Nafisa Ahmed, Abida Nurun Nahar, Tanzina Akter   +6 more
doaj   +1 more source

Effect of sciadopitysin on sodium arsenite-induced senescence of rat hippocampal neurons

环境与职业医学, 2022
BackgroundIn addition to the typical signs of skin damage, long-term arsenic exposure is often accompanied by signs and symptoms of neurobehavioral abnormalities.ObjectiveTo investigate potential intervention effect of sciadopitysin on senescence of ...
Cheng CHEN, Xiong CHEN, Aihua ZHANG
doaj   +1 more source