Results 21 to 30 of about 316 (98)
Frontiers in Pharmacology, 2022 CYP3A4-mediated Phase I biotransformation is the rate-limiting step of elimination for many commonly used clinically agents. The modulatory effects of herbal medicines on CYP3A4 activity are one of the risk factors affecting the safe use of drug and ...
Bo Wang +18 more
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In silico molecular docking and ADMET prediction of Ginkgo biloba biflavonoids as dual inhibitors of human HMG-CoA reductase and α-amylase [PDF]
Journal of the Serbian Chemical SocietyThere is an increasing interest in investigating phytochemicals as inhibitors of HMG-CoA reductase (HMGR) and α-amylase enzymes. Inhibition of these enzymes helps manage hypercholesterolemia and diabetes by reducing cholesterol synthesis and blood sugar ...
Agosto Nesteve John B.
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Computer-assisted evaluation of plant-derived β-secretase inhibitors in Alzheimer’s disease
Egyptian Journal of Medical Human Genetics, 2021 Background Alzheimer’s disease (AD) is a progressive neurodegenerative age-related dementia that results in memory loss of elderly people. Many hypotheses have been formally articulated till now to decipher the pathogenesis of this disease.
Md. Asad Ullah +6 more
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Effect of sciadopitysin on sodium arsenite-induced senescence of rat hippocampal neurons
环境与职业医学, 2022 BackgroundIn addition to the typical signs of skin damage, long-term arsenic exposure is often accompanied by signs and symptoms of neurobehavioral abnormalities.ObjectiveTo investigate potential intervention effect of sciadopitysin on senescence of ...
Cheng CHEN, Xiong CHEN, Aihua ZHANG
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Anticancer Effects of Five Biflavonoids from Ginkgo Biloba L. Male Flowers In Vitro
Molecules, 2019 Ginkgo biloba L., an ancient dioecious gymnosperm, is now cultivated worldwide for landscaping and medical purposes. A novel biflavonoid—amentoflavone 7′′-O-β-d-glucopyranoside (1)—and four known biflavonoids were isolated ...
Min Li +7 more
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Journal of Cellular and Molecular Medicine, Volume 24, Issue 20, Page 11922-11935, October 2020., 2020 Abstract Selaginella moellendorffii Hieron. (SM), a perennial evergreen plant, has been used in the treatment of acute infectious hepatitis, thoracic and hypochondriac lumbar contusions, systemic oedema and thrombocytopaenia. However, the role of a biflavonoid‐rich extract from SM (SM‐BFRE) in anti‐larynx cancer has rarely been reported. In this study,
Huiqi Huang +8 more
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BioMed Research International, Volume 2018, Issue 1, 2018., 2018 In the present study, the process of ultrasound‐assisted extraction (UAE) followed by macroporous resin purification was successfully developed to achieve maximal recovery of functional components (flavonoids and ginkgolides) with minimal contents of toxic components (alkylphenols) from Ginkgo biloba leaves.
Guisheng Zhou +8 more
wiley +1 more source
eFood, Volume 7, Issue 1, February 2026.Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram +6 more
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Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics
Proteins: Structure, Function, and Bioinformatics, Volume 93, Issue 8, Page 1314-1329, August 2025.Abstract Before the controversial approval of humanized monoclonal antibody lecanemab, which binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for Alzheimer's disease (AD) were symptomatic. The researchers are still struggling to find a breakthrough in AD therapeutic medicine, which is partially attributable to lack in ...
Sharif Arar +2 more
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A Phytopharmacological Review on a Medicinal Plant: Juniperus communis
International Scholarly Research Notices, Volume 2014, Issue 1, 2014., 2014 Juniperus communis is a shrub or small evergreen tree, native to Europe, South Asia, and North America, and belongs to family Cupressaceae. It has been widely used as herbal medicine from ancient time. Traditionally the plant is being potentially used as antidiarrhoeal, anti‐inflammatory, astringent, and antiseptic and in the treatment of various ...
Souravh Bais +4 more
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