Results 61 to 70 of about 394,621 (339)

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Detection of Contact Binary Candidates Observed By TESS Using the Autoencoder Neural Network

open access: yesThe Astronomical Journal
A contact binary may be the progenitor of a red nova that eventually produces a merger event and have a cut-off period of around 0.2 days. Therefore, a large number of contact binaries is needed to search for the progenitor of red novae and to study the ...
Xu Ding   +3 more
doaj   +1 more source

Stellar Properties of Observed Stars Stripped in Binaries in the Magellanic Clouds

open access: yesThe Astrophysical Journal, 2023
Massive stars (∼8–25 M _⊙ ) stripped of their hydrogen-rich envelopes via binary interaction are thought to be the main progenitors for merging neutron stars and stripped-envelope supernovae.
Y. Götberg   +8 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Quasi-binarity of massive stars in young dense clusters - the case of the ONC

open access: yes, 2007
Observations indicate that in young stellar clusters the binary fraction for massive stars is higher than for solar mass stars. For the Orion Nebula Cluster (ONC) there is a binary frequency of ~ 50% for solar-mass stars compared to 70-100% for the ...
Olczak, C., Pfalzner, S.
core   +1 more source

Red-giant stars in eccentric binaries [PDF]

open access: yes, 2014
The unparalleled photometric data obtained by NASA’s Kepler Space Telescope has led to improved understanding of red-giant stars and binary stars. We discuss the characterization of known eccentric system, containing a solar-like oscillating red-giant ...
Beck   +16 more
core   +3 more sources

Detection of Semidetached Eclipsing Binaries from TESS

open access: yesThe Astronomical Journal
Semidetached binaries, distinguished by their mass transfer phase, play a crucial role in elucidating the physics of mass transfer within interacting binary systems.
Xu Ding   +6 more
doaj   +1 more source

Distinguishing binary neutron star from neutron star-black hole mergers with gravitational waves [PDF]

open access: yesThe Astrophysical Journal Letters, 893, 2, L41, 2020, 2019
The gravitational-wave signal from the merger of two neutron stars cannot be easily differentiated from the signal produced by a comparable-mass mixed binary of a neutron star and a black hole. Indeed, both binary types can account for the gravitational-wave signal GW170817 even if its electromagnetic counterpart emission is taken into account.
arxiv   +1 more source

Binary Statistics and Star Formation [PDF]

open access: yesAstrophysics and Space Science, 1984
AbstractBinary statistics, in particular the distributions of mass ratios and orbital periods, are reviewed in an attempt to obtain clues to possible star formation and cloud fragmentation processes. Various observational selection effects which hamper the establishment of the true distributions are discussed.
openaire   +3 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

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