Results 241 to 250 of about 2,617,421 (301)

Intracellular Retinoid-Binding Proteins (CRBP, CRALBP, CRABP) as Emerging Drug Targets in Retinal Disease. [PDF]

Int J Mol Sci
Regmi Bagale L, Kim HJ.
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Competition in drug binding and … the race to equilibrium

Fundamental & Clinical Pharmacology, 2022
AbstractBinding kinetics has become a popular topic in pharmacology due to its potential contribution to the selectivity and duration of drug action. Yet, the overall kinetic aspects of complex binding mechanisms are still merely described in terms of elaborate algebraic equations.
Georges Vauquelin, Dominique Maes
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Competitive binding assays for riboflavin and riboflavin-binding protein

Analytical Biochemistry, 1982
Abstract A competitive binding procedure that can be used to determine either riboflavin or riboflavin-binding protein has been developed. Riboflavin-binding protein from chicken egg white binds tightly to DEAE-cellulose while free riboflavin does not.
S E, Lotter, M S, Miller, R C, Bruch, H B, White   +3 more
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Competitive hapten-antibody binding: Solution of the binding equation

Journal of Theoretical Biology, 1965
Abstract The competitive binding equation which describes the reactions between two univalent homogeneous cross-reacting haptens and antibody heterogeneous with respect to equilibrium constants has been solved. The joint probability density function of equilibrium constants can be computed directly from binding measurements; no assumption about the ...
J, Wong, F, Aladjem
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ASSAY OF ALDOSTERONE BY COMPETITIVE PROTEIN BINDING

Acta Endocrinologica, 1970
ABSTRACT We have applied a competitive protein binding technique to the assay of aldosterone, utilizing the aldosterone binding protein (ABP) in kidney as the specific receptor molecule. Intracellular ABP was obtained from the homogenization of adrenalectomized rat kidneys in 0.25 M sucrose.
R G, Robinson, D D, Fanestil
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Effect of transport and competition on ligand binding

Biophysical Chemistry, 1999
We present a model to describe the physics of chemoreception in processes determined by competitive ligand binding. Our model describes the competition between various populations, such as ligands vs. blockers and receptors vs. decoys, in protein activation when diffusion is rate-determining.
C. A. CONDAT, DELSANTO, PIER PAOLO, E. RUFFINO, G. PEREGO   +3 more
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TESTOSTERONE ASSAYS BY COMPETITIVE PROTEIN BINDING

Acta Endocrinologica, 1970
ABSTRACT A review of competitive protein binding methods for the determination of testosterone in plasma is given. The different steps discussed are: Choice of the binding protein, dilution of the protein solution, separation of the free from the bound fraction, purification of the extract and factors determining the blank.
A, Vermeulen, L, Verdonck
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Competitive Protein Binding Assay for Piritrexim

Journal of Pharmaceutical Sciences, 1989
A competitive protein binding assay for piritrexim (PTX, 1) that makes use of a commercially available radioassay kit for methotrexate has been developed. After it is selectively extracted from plasma, PTX competes with [125l]methotrexate for binding to dihydrofolate reductase isolated from Lactobacillus casei. Free drug is separated from bound drug by
J L, Woolley, J L, Ringstad, C W, Sigel
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Competitive protein binding assay of corticosterone

Journal of Steroid Biochemistry, 1972
Abstract Details of a competitive protein binding assay of corticosterone are described. The preliminary TLC separation permits simultaneous estimation of corticosterone, aldosterone and progesterone. “Unstressed” rat plasma corticosterone values were obtained between 0.3 and 9 μg/ 100 ml.
A, Spät, S, Józan
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Cefmenoxime and Bilirubin: Competition for Albumin Binding

Pharmacology & Toxicology, 1991
Abstract:Certain drugs are known to compete with bilirubin for albumin binding; therefore, all drugs administered to neonates should be tested to determine the degree of competition. The effect of cefmenoxime on bilirubin‐albumin binding was determined by comparing the oxidation rate of free bilirubin in the presence and absence of drug.
D L, Onks, J F, Harris, A F, Robertson
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