Results 101 to 110 of about 6,669,365 (283)

Cholinium-Based Ionic Liquids Modulate Protein Stability: A Comparative Study of Enzymes and Albumins

open access: yesMolecules
This work aims to assess the intermolecular interaction of choline ionic liquids (ILs) (choline malonate ([Ch][Mal]), choline succinate ([Ch][Suc]), and choline valinate ([Ch][Val]) with two enzymes (lysozyme and α-chymotrypsin).
Artashes A. Khachatrian   +9 more
doaj   +1 more source

Investigating ideomotor cognition with motorvisual priming paradigms: Key findings, methodological challenges, and future directions

open access: yesFrontiers in Psychology, 2012
Ideomotor theory claims that perceptual representations of action effects are functionally involved in the planning of actions. Strong evidence for this claim comes from a phenomenon called motorvisual priming.
Roland eThomaschke
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

"Algún" indefinite is not bound by adverbs of quantification

open access: yesIsogloss, 2021
Some indefinites cannot be bound by adverbs of quantification or the generic operator. I argue that this datum follows from the internal syntax of indefinites: only those indefinites consisting of a minimal structure can be bound, bigger indefinites ...
Luis López
doaj  

Rac1 S71 Mediates the Interaction between Rac1 and 14-3-3 Proteins

open access: yesCells, 2019
Both 14-3-3 proteins (14-3-3s) and Rho proteins regulate cytoskeleton remodeling and cell migration, which suggests a possible interaction between the signaling pathways regulated by these two groups of proteins.
Abdalla Abdrabou   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Overt pronouns in null subject languages: an experimental investigation of Kashubian, Polish, and Silesian

open access: yesLinguistics
Interpretive differences between overt subject pronouns relative to null subject pronouns are commonly considered a defining property of Consistent Null Subject Languages (CNSLs), in contradistinction to Partial Null Subject Languages (PNSLs).
Ruda Marta, Huang Nick
doaj   +1 more source

A novel fluorescent probe, triphenylamine rhodamine-3-acetic acid (mRA) for the detection of Amyloid-β aggregates in Alzheimer's disease

open access: yesFrontiers in Neuroscience
Amyloid-β (Aβ) is implicated in the pathophysiology of Alzheimer's disease (AD) and plays a significant role in neuronal degeneration. Aβ in solution is essential during the initial stages of developing lead compounds that influence Aβ fibrillation.
Raja Chinnappan   +10 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Combining Chloride Migration and Diffusion Tests to Estimate Freundlich Chloride Binding Parameters and Improve Predictions of Chloride Ingress

open access: yesNordic Concrete Research
Chloride binding plays a major role with respect to chloride ingress. On one hand, engineering models often rely on “apparent” diffusion coefficients, which account for both the diffusion of chlorides in the pore solution and chloride binding.
Ranger Maxime   +3 more
doaj   +1 more source

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