Results 101 to 110 of about 4,288,984 (317)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
LinguisticsInterpretive differences between overt subject pronouns relative to null subject pronouns are commonly considered a defining property of Consistent Null Subject Languages (CNSLs), in contradistinction to Partial Null Subject Languages (PNSLs).
Ruda Marta, Huang Nick
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Frontiers in NeuroscienceAmyloid-β (Aβ) is implicated in the pathophysiology of Alzheimer's disease (AD) and plays a significant role in neuronal degeneration. Aβ in solution is essential during the initial stages of developing lead compounds that influence Aβ fibrillation.
Raja Chinnappan +10 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Two time constants for the binding of proteins to DNA from micromechanical data [PDF]
, 2000 Recent experimental advances allow the direct measurement of the force/extension behavior for DNA in the presence of strongly binding proteins. Such experiments reveal information about the cooperative mechanism of protein binding.
Turner, Matthew S., Matthew S. Turner
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Nordic Concrete ResearchChloride binding plays a major role with respect to chloride ingress. On one hand, engineering models often rely on “apparent” diffusion coefficients, which account for both the diffusion of chlorides in the pore solution and chloride binding.
Ranger Maxime +3 more
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Neuron, 1999 Both Ghose and Maunsell and Shadlen and Movshon point out what is perhaps the fundamental problem with the binding hypothesis: even supposing that temporal coding is the vehicle for signaling which neural populations should be bound together, the theory does not adequately address how those combinations are computed.
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Structural and functional studies of intrinsically disordered fibronectin-binding proteins [PDF]
, 2009 Bacterial fibronectin-binding proteins (FnBPs) mediate adhesion of bacteria to host tissues through binding to the human protein fibronectin (Fn). FnBPs are predicted to contain a series of intrinsically disordered Fn-binding repeats (FnBRs), which ...
Norris, Nicole Catherine
core