Results 61 to 70 of about 8,384,443 (422)

The Integration of Realistic Episodic Memories Relies on Different Working Memory Processes: Evidence from Virtual Navigation

open access: yesFrontiers in Psychology, 2018
Memory is one of the most important cognitive functions in a person’s life as it is essential for recalling personal memories and performing many everyday tasks.
Gaën Plancher   +8 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Public health careers: mapping information, informing practitioner needs [PDF]

open access: yes, 2016
Public health promotion and ill health prevention is a key priority for the NHS. The public health workforce is central to achieving improved health outcomes for a diverse and changing population.
Binding, Charlene   +2 more
core   +1 more source

Water-resistant gypsum binder

open access: yesMATEC Web of Conferences, 2016
The authors developed a multi-component gypsum binder (MGB) with an improved (by 1.8 to 2.2 times) water resistance value in comparison with the initial gypsum and a softening factor value within the range of 0.85 to 0.91 through the introduction of a ...
Panchenko Alexander I., Kozlov Nikita
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Adaptive evolution of transcription factor binding sites [PDF]

open access: yes, 2004
The regulation of a gene depends on the binding of transcription factors to specific sites located in the regulatory region of the gene. The generation of these binding sites and of cooperativity between them are essential building blocks in the ...
Berg, Johannes   +2 more
core   +4 more sources

Hepatoprotective Effects of Met-enkephalin on Acetaminophen-Induced Liver Lesions in Male CBA Mice

open access: yesMolecules, 2014
Recent histopathological investigations in patients with hepatitis suggested possible involvement of Met-enkephalin and its receptors in the pathophysiology of hepatitis.
Roko Martinić   +9 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

S100 Proteins—Intracellular and Extracellular Function in Norm and Pathology

open access: yesBiomolecules
The S100 proteins are small, ubiquitous, mostly homodimeric proteins containing two EF-hand structures, that is, helix-loop-helix motifs specialized in high-affinity calcium-binding (~10−6 M) [...]
Wiesława Leśniak, Anna Filipek
doaj   +1 more source

ERPs reveal the time-course of aberrant visual-phonological binding in developmental dyslexia

open access: yesFrontiers in Human Neuroscience, 2016
New evidence is accumulating for a deficit in binding visual-orthographic information with the corresponding phonological code in developmental dyslexia.
Manon Wyn Jones   +2 more
doaj   +1 more source

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