Results 61 to 70 of about 8,384,443 (422)
Memory is one of the most important cognitive functions in a person’s life as it is essential for recalling personal memories and performing many everyday tasks.
Gaën Plancher+8 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Public health careers: mapping information, informing practitioner needs [PDF]
Public health promotion and ill health prevention is a key priority for the NHS. The public health workforce is central to achieving improved health outcomes for a diverse and changing population.
Binding, Charlene+2 more
core +1 more source
The authors developed a multi-component gypsum binder (MGB) with an improved (by 1.8 to 2.2 times) water resistance value in comparison with the initial gypsum and a softening factor value within the range of 0.85 to 0.91 through the introduction of a ...
Panchenko Alexander I., Kozlov Nikita
doaj +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Adaptive evolution of transcription factor binding sites [PDF]
The regulation of a gene depends on the binding of transcription factors to specific sites located in the regulatory region of the gene. The generation of these binding sites and of cooperativity between them are essential building blocks in the ...
Berg, Johannes+2 more
core +4 more sources
Hepatoprotective Effects of Met-enkephalin on Acetaminophen-Induced Liver Lesions in Male CBA Mice
Recent histopathological investigations in patients with hepatitis suggested possible involvement of Met-enkephalin and its receptors in the pathophysiology of hepatitis.
Roko Martinić+9 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
S100 Proteins—Intracellular and Extracellular Function in Norm and Pathology
The S100 proteins are small, ubiquitous, mostly homodimeric proteins containing two EF-hand structures, that is, helix-loop-helix motifs specialized in high-affinity calcium-binding (~10−6 M) [...]
Wiesława Leśniak, Anna Filipek
doaj +1 more source
ERPs reveal the time-course of aberrant visual-phonological binding in developmental dyslexia
New evidence is accumulating for a deficit in binding visual-orthographic information with the corresponding phonological code in developmental dyslexia.
Manon Wyn Jones+2 more
doaj +1 more source