Results 241 to 250 of about 8,730,538 (402)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

An Orc6 tether mediates ORC binding-site switching during replication origin licensing. [PDF]

Proc Natl Acad Sci U S A
Driscoll D, Friedman LJ, Gelles J, Bell SP.   +3 more
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

The structural effects of indel polymorphisms outside the binding site on RNA-protein interactions are shaped by selection. [PDF]

PLoS Comput Biol
Owusu-Ansah C, Shatoff E, Bundschuh R.
europepmc   +1 more source

A second guanyl nucleotide-binding site associated with adenylate cyclase. Distinct nucleotides activate adenylate cyclase and permit ADP-ribosylation by cholera toxin.

, 1983
D. Michael Gill, Roberta Meren
openalex   +1 more source

Localization of binding sites in protein structures by optimization of a composite scoring function [PDF]

, 2006
Andrea Rossi, Marc A. Martí‐Renom, Andrej Šali   +2 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Identification of the client-binding site on the Golgi membrane protein adaptor Vps74/yGOLPH3. [PDF]

iScience
Lesniak AM, Ye Z, Banfield DK.
europepmc   +1 more source

Faculty Opinions recommendation of Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.

, 2008
Titia K. Sixma
openalex   +2 more sources

LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor [PDF]

, 2018
Farah Deba, Hamed I. Ali, Abisola Tairu, Kara Ramos, Jihad Ali, Ayman K. Hamouda   +5 more
openalex   +1 more source