Results 41 to 50 of about 126,005 (293)
Ethanol binding sites on proteins
Journal of Molecular Graphics and Modelling, 2017 This study is on the analysis of ethanol binding sites on 3D structures of nonredundant proteins from the Protein Data Bank. The only one amino acid residue that is significantly overrepresented around ethanol molecules is Tyr. There are usually two or more Tyr residues in the same ethanol binding site, while residues of Thr, Asp and Gln are ...
Khrustalev, V. V. +2 more
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Molecules, 2023 The interaction of indomethacin with human serum albumin (HSA) has been studied here considering the primary and secondary binding sites. The Stern–Volmer plots were linear in the lower concentration range of indomethacin while a downward curvature was ...
Mohd Sajid Ali +5 more
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A client‐binding site of Cdc37 [PDF]
The FEBS Journal, 2005 The molecular chaperone Hsp90 is distinct from Hsp70 and chaperonin in that client proteins are apparently restricted to a subset of proteins categorized as cellular signaling molecules. Among these, many specific protein kinases require the assistance of Hsp90 and its co‐chaperone Cdc37/p50 for their biogenesis.
Kazuya Terasawa, Yasufumi Minami
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Functional microRNA binding site variants
Molecular Oncology, 2019 Germline single nucleotide polymorphisms are one of the most common genetic variations. Polymorphisms that cause nonsynonymous mutations in gene coding regions are known to cause serious deleterious downstream effects.
Ye Yuan, Joanne B. Weidhaas
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Anais da Academia Brasileira de Ciências, 2015 RESUMO Dois genes de α-actina do peixe Leporinus macrocephalus, referindo-se aos tecidos musculares branco e vermelho, foram isolados. Isoformas de actinas, que principalmente diferiram por uma substituição Ser/Ala155, podem ter uma significância ...
FERNANDA A. ALVES-COSTA +2 more
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Recent Advancements in Aptamer-Based Surface Plasmon Resonance Biosensing Strategies
Biosensors, 2021 Surface plasmon resonance (SPR) can track molecular interactions in real time, and is a powerful as well as widely used biological and chemical sensing technique.
Chia-Chen Chang
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Return of the Electric Binding Site [PDF]
The Journal of General Physiology, 2008 The BK-type Ca2+-activated K+ channel has been the subject of increasingly detailed mechanistic study since the first recordings of this channel were obtained more than 25 years ago (Pallotta et al., 1981; Latorre et al., 1982; Magleby, 2003; and references therein).
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Promiscuity of the Euonymus Carbohydrate-Binding Domain
Biomolecules, 2012 Plants synthesize small amounts of carbohydrate-binding proteins on exposure to stress. For example, on exposure to drought, high salt, wounding and by treatment with some plant hormones or by pathogen attack. In contrast to the ‘classical’ plant lectins
Els J.M. Van Damme, Elke Fouquaert
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Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [PDF]
arXiv, 2021 We calculated the patterns for the CCCTC transcription factor (CTCF) binding sites across many genomes on a first principle approach. The validation of the first principle method was done on the human as well as on the mouse genome. The predicted human CTCF binding sites are consistent with the consensus sequence, ChIP-seq data for the K562 cell ...
arxiv
The Na+ Binding Site of Thrombin [PDF]
Journal of Biological Chemistry, 1995 Thrombin is an allosteric serine protease existing in two forms, slow and fast, targeted toward anticoagulant and procoagulant activities. The slow --> fast transition is induced by Na+ binding to a site contained within a cylindrical cavity formed by three antiparallel beta-strands of the B-chain (Met180-Tyr184a, Lys224-Tyr228, and Val213-Gly219 ...
Enrico Di Cera +6 more
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