Results 61 to 70 of about 8,774,932 (333)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

TFEBexplorer: An integrated tool to study genes regulated by the stress-responsive Transcription Factor EB

open access: yesAutophagy Reports, 2022
TFEBexplorer is a comprehensive web-tool to study genes modulated by the transcription factor EB (TFEB), a master regulator of lysosomal biogenesis and autophagy, that integrates multiple datasets following genetic perturbation of TFEB with ...
Rossella De Cegli   +7 more
doaj   +1 more source

Phosphorus Sorption following the Application of Charcoal and Sago (Metroxylon sagu) Bark Ash to Acid Soils

open access: yesAgronomy, 2022
Acidic cations such as Al, Fe, and Mn tend to fix P in soils, and this reaction make P unavailable for plant uptake. Several conventional strategies for farmers had been proposed to ameliorate Al toxicity either via liming or continuous P fertilization ...
Prisca Divra Johan   +7 more
doaj   +1 more source

Rubredoxin Variant Folds without Iron [PDF]

open access: yes, 1999
Pyroccocus furiosus rubredoxin (PFRD), like most studied hyperthermophilic proteins, does not undergo reversible folding. The irreversibility of folding is thought to involve PFRD’s iron-binding site.
Mayo, Stephen L., Strop, Pavel
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Inferring Binding Energies from Selected Binding Sites

open access: yesPLoS Computational Biology, 2009
We employ a biophysical model that accounts for the non-linear relationship between binding energy and the statistics of selected binding sites. The model includes the chemical potential of the transcription factor, non-specific binding affinity of the protein for DNA, as well as sequence-specific parameters that may include non-independent ...
Zhao, Yue, Granas, David, Stormo, Gary D
openaire   +5 more sources

Unraveling determinants of transcription factor binding outside the core binding site

open access: yesGenome Research, 2015
Binding of transcription factors (TFs) to regulatory sequences is a pivotal step in the control of gene expression. Despite many advances in the characterization of sequence motifs recognized by TFs, our ability to quantitatively predict TF binding to ...
M. Levo   +9 more
semanticscholar   +1 more source

RNA-Binding protein HuR and the members of miR-200 family play an unconventional role in the regulation of c-Jun mRNA [PDF]

open access: yes, 2016
Post-transcriptional gene regulation is a fundamental step for coordinating cellular response in a variety of processes. RNA-binding proteins (RBPs) and microRNAs (miRNAs) are the most important factors responsible for this regulation.
BOZZONI, Irene   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Detailed Experimental and In Silico Investigation of Indomethacin Binding with Human Serum Albumin Considering Primary and Secondary Binding Sites

open access: yesMolecules, 2023
The interaction of indomethacin with human serum albumin (HSA) has been studied here considering the primary and secondary binding sites. The Stern–Volmer plots were linear in the lower concentration range of indomethacin while a downward curvature was ...
Mohd Sajid Ali   +5 more
doaj   +1 more source

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