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Engineering of an Fc-specific monovalent protein G for the light-controlled affinity purification of antibodies. [PDF]

Sci Rep
Mayrhofer P, Skerra A.
europepmc   +1 more source

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Structure, function and properties of antibody binding sites.

Journal of Molecular Biology, 1991
Do antibody combining sites possess general properties that enable them to bind different antigens with varying affinities and to bind novel antigens? Here, we address this question by examining the physical and chemical characteristics most favourable for residues involved in antigen accommodation and binding.
IS Mian, A. Bradwell, A. Olson
semanticscholar   +3 more sources

Specific suppression by anti-binding site antibody

Cellular Immunology, 1975
Heterologous antisera against the binding site of different phosphorylcholine BALB/c myeloma proteins, TEPC-15, MOPC-167, and McPC-603, were prepared by absorption on TEPC-15-Sepharose in the presence of hapten. The binding of the absorbed anti-TEPC-15 to 125I-(Fab)2 TEPC-15 is inhibitable by unlabeled phosphorylcholine myeloma proteins and by hapten ...
Kohler, H, Smyk, S, Kluskens, L
openaire   +2 more sources