Results 151 to 160 of about 1,682,340 (366)

Differences between high-affinity forskolin binding sites in dopamine-rich and other regions of rat brain [PDF]

, 1988

openalex   +1 more source

Decision letter for "Mapping co‐regulatory interactions among ligand‐binding sites in ryanodine receptor 1"

, 2021

openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Identification of High Affinity Fatty Acid Binding Sites on Human Serum Albumin by MM-PBSA Method [PDF]

Human serum albumin (HSA) has seven common fatty acid (FA) binding sites. In this study, we used the molecular mechanics Poisson-Boltzmann surface area method to identify high affinity FA binding sites on HSA in terms of binding free energy.
Fujiwara, Shin-ichi, 100000236, 4875, 00362880, 20231996, 96, Amisaki, Takashi, 100000075   +7 more
core  

Evidence for presence of an arginine residue in the coenzyme A binding site of choline acetyltransferase.

, 1981
Henry G. Mautner, A A Pakula, Robert E. Merrill   +2 more
openalex   +2 more sources

A comparison of direct and indirect techniques using ferritin-conjugated ligands for the localization of concanavalin A binding sites on isolated hepatocyte plasma membranes. [PDF]

, 1983
Joseph V. Briggman, Christopher C. Widnell   +1 more
openalex   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat
Cancer immunotherapy has appeared as a prospective therapeutic modality. Therapeutic antibodies induced in an in vitro expression system act as “targeting missiles” against tumor‐associated binding sites, and subsequently, immune system attack on tumors ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
doaj   +1 more source

The binding site for the liver-specific transcription factor Tf-LF1 and the TATA box of the human transferrin gene promoter are the only elements necessary to direct liver-specific transcriptionin vitro

, 1990
Daniel Mendelzon, F. Boissier, Mario M. Zakin   +2 more
openalex   +2 more sources

Identification of Pterin Binding Sites on Class I HLA Molecules Associated with the Interleukin 2 Receptor [PDF]

, 1991
Irmgard Ziegler, Richard G.H. Cotton, Ian G. Jennings   +2 more
openalex   +1 more source