Results 151 to 160 of about 5,097,951 (211)

Correction: Widespread 3'UTR capped RNAs derive from G-rich regions in proximity to AGO2 binding sites. [PDF]

BMC Biol
Haberman N, Digby H, Faraway R, Cheung R, Chakrabarti AM, Jobbins AM, Parr C, Yasuzawa K, Kasukawa T, Yip CW, Kato M, Takahashi H, Carninci P, Vernia S, Ule J, Sibley CR, Martinez-Sanchez A, Lenhard B.   +17 more
europepmc   +1 more source

Master of Metals2: a graph neural network based architecture for the prediction of zinc binding sites in protein structures. [PDF]

Brief Bioinform
Laveglia V, Ciofalo C, Morelli E, Andreini C, Rosato A.   +4 more
europepmc   +1 more source

Identifying potential binding sites for complex formation between Tyrosyl-DNA phosphodiesterase 1 and poly [ADP-ribose] polymerase 1.

Phys Chem Chem Phys
Wang S, Üren A, Tiwari PB.
europepmc   +1 more source

Systematic structural and functional analysis of metal-binding sites in native proteomes

Quast J, Pagotto A, Separovich R, Dünnebacke M, Gillet L, Luo X, Züger E, Magnusson G, Correia M, Ciofalo C, Andreini C, Rosato A, Beltrao P, Zamboni N, de Souza N, Picotti P.   +15 more
europepmc   +1 more source

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Localization of the binding site on fibrin for the secondary binding site of thrombin

Biochemistry, 1988
Affinity chromatography of active site inhibited thrombin on immobilized fragments derived from the central (desAB-NDSK) and terminal (D1) globular domains of fibrinogen revealed that the site responsible for the binding of thrombin at its secondary fibrin binding site is located in the central domain.
Z, Vali, H A, Scheraga
openaire   +2 more sources

Cryptophycin 1 binds to tubulin at a site distinct from the colchicine binding site and at a site that may overlap the vinca binding site

Cancer Letters, 1996
Cryptophycin 1 is a new cytotoxic antimicrotubule agent with excellent antitumor activity. The methods of Sackett (Biochemistry, 34, 7010-7019, 1995), utilizing the selective and specific proteolysis of alpha- and beta-tubulin by trypsin and chymotrypsin, was used to identify the cryptophycin 1 binding site on tubulin.
S L, Mooberry, C R, Taoka, L, Busquets
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Benzodiazepine-Binding Site and Gaba-Binding Site

1983
There is a body of experimental evidence to suggest that the benzodiazepine-binding site, the GABA-binding site and the chloride ionophore are functionally correlated. To elucidate this issue, the interactions among these components in both membrane-bound state and soluble state are examined.
Li-ren Chang, Eric A. Barnard
openaire   +1 more source

Antibody Binding Sites

1996
This chapter assesses advances in the understanding and manipulation of antibody binding sites and variable regions. The antigen binding region of an antibody reduced to a 25-kDa minimum comprises of a noncovalent heterodimer of V H and V L domains.
J S, Huston, M N, Margolies, E, Haber
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What makes a binding site a binding site?

Current Opinion in Structural Biology, 1995
Organic probe molecules have recently been used to define hydrophobic binding sites on the surface of proteins. It appears that the presence of water on the surface of a protein plays a crucial role in the interaction between that protein and its binding site.
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Anatomy of lipase binding sites: the scissile fatty acid binding site

Chemistry and Physics of Lipids, 1998
Shape and physico-chemical properties of the scissile fatty acid binding sites of six lipases and two serine esterases were analyzed and compared in order to understand the molecular basis of substrate specificity. All eight serine esterases and lipases have similar architecture and catalytic mechanism of ester hydrolysis, but different substrate ...
J, Pleiss, M, Fischer, R D, Schmid
openaire   +2 more sources