Results 161 to 170 of about 5,097,951 (211)

Melatonin Binding Sites

Journal of Neurochemistry, 1988
Abstract: The distribution and characterization of specific melatonin binding sites were studied using 125I‐melatonin. Autoradiography revealed only three sites of specific melatonin binding in brain: the suprachiasmatic nuclei, the median eminence, and the small part of choroid plexus at the caudal end of the fourth ventricle.
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Interaction of the dibutylchloromethyltin chloride binding site with the carbodiimide binding site in mitochondria

Biochemical and Biophysical Research Communications, 1980
Abstract An examination of the effect of dibutylchloromethyltin/chloride on the carbodiimide binding proteolipid of mitrochondrial ATPase has revealed that in the presence of the alkyltin, (1) binding of dicyclohexycarbodiimide is decreased (2) the electron spin resonance spectrum of a nitroxide analogue of dicyclohexylcarbodiimide exhibits line ...
M D, Partis, E, Bertoli, D E, Griffiths, A, Azzi   +3 more
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Rhizoxin binding to tubulin at the maytansine-binding site

Biochimica et Biophysica Acta (BBA) - General Subjects, 1987
The binding of rhizoxin, a potent inhibitor of mitosis and in vitro microtubule assembly, to porcine brain tubulin was studied. Tubulin possesses one binding site for rhizoxin per molecule with a dissociation constant (Kd) of 1.7.10(-7) M. Ansamitocin P-3, a homologue of maytansine, was a competitive inhibitor of rhizoxin binding, with an inhibition ...
M, Takahashi, S, Iwasaki, H, Kobayashi, S, Okuda, T, Murai, Y, Sato   +5 more
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Hormone binding site of corticosteroid binding globulin

Nature Structural & Molecular Biology, 1995
A new location for the hormone-binding site of corticosteroid binding globulin is propose based on experimental data, together with a sequence and structural alignment of the serpin ...
P, Edgar, P, Stein
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Ligand Binding With Continuous Modification of Binding Sites

Journal of Biomolecular Structure and Dynamics, 2004
Simultaneous formulation binding and structure modification of the binding site leads to binding process that can be analyzed within the framework of the non-linear theory of dynamic systems. Such an approach allows us to obtain several properties of the binding center: plurality of stationary (stable and unstable) states at binding, recognition of ...
V B, Arakelyan, S G, Haroutiunian, H H, Abgaryan, A V, Arakelyan, T S, Haroutunyan   +4 more
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Metal-binding sites in proteins

Current Opinion in Biotechnology, 1991
A dramatic increase in the number of solved metalloprotein structures and recent breakthroughs in structural analysis have provided a sufficiently detailed understanding of the structural chemistry of some metal-binding sites to allow successful design.
J A, Tainer, V A, Roberts, E D, Getzoff
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The binding site for C1q on IgG

Nature, 1988
In humoral defence, pathogens are cleared by antibodies acting as adaptor molecules: they bind to antigen and trigger clearance mechanisms such as phagocytosis, antibody-dependent cell-mediated cytotoxicity and complement lysis. The first step in the complement cascade is the binding of C1q to the antibody.
A R, Duncan, G, Winter
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Ethanol binding sites on proteins

Journal of Molecular Graphics and Modelling, 2017
This study is on the analysis of ethanol binding sites on 3D structures of nonredundant proteins from the Protein Data Bank. The only one amino acid residue that is significantly overrepresented around ethanol molecules is Tyr. There are usually two or more Tyr residues in the same ethanol binding site, while residues of Thr, Asp and Gln are ...
Khrustalev, V. V., Khrustaleva, T. A., Lelevich, S. V.   +2 more
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On the receptor binding site of relaxins

International Journal of Peptide and Protein Research, 1988
Relaxin plays a critical role in viviparity and has recently been implicated as a hormone of oviparity as well. In most mammals relaxin causes the widening of the birth canal during parturition and suppresses uterine motility during pregnancy. Relaxins isolated from several species have shown a great deal of sequence variability, and speculations ...
E E, Büllesbach, C, Schwabe
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Mitochondrial Binding Sites for Triiodothyronine

Endocrinology, 1978
Metabolic effects upon rat liver mitochondria have been observed by others within 2 min of injection of massive amounts of L-T4. Reported here is the subcellular distribution of 2--5 ng high specific activity [125I]L-T3 2 min after ip injection with and without a loading dose of 30 micrograms unlabeled T3.
R L, Greif, D, Sloane
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