Results 171 to 180 of about 5,097,951 (211)
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Substrate-binding sites in acetylcholinesterase
Trends in Pharmacological Sciences, 1991Acetylcholinesterase is among the most efficient enzymes known. In order to provide an explanation for its catalytic and regulatory mechanisms, including the high turnover rate, the specific amino acid residues involved in substrate binding and hydrolysis need to be identified.
F, Hucho, J, Järv, C, Weise
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Echinomycin Binding Sites on DNA
Science, 1984The preferred binding sites of echinomycin on DNA can be determined by a method called "footprinting." A 32 P end-labeled restriction fragment from pBR322 DNA is protected by binding to echinomycin, and cleaved by a synthetic DNA cleaving reagent, methidiumpropyl--EDTA⋅Fe(II); the DNA cleavage products are then ...
Van Dyke, Michael M., Dervan, Peter B.
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A Binding Site for Chlorambucil on Metallothionein
Biochemistry, 1996It is of interest to test the hypothesis that induced metallothionein (MT) acts in acquired drug resistance by covalent sequestration. In this study MT was incubated in vitro with chlorambucil (CHB) under conditions where only 1:1 covalent adducts were formed.
J, Zaia +6 more
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Database Searches for Binding Sites
Science, 2000In their Report “Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons” (7 Apr., p. [136][1]), G. G. Loots and colleagues identify conserved noncoding sequences (CNSs) in orthologous regions of the interleukin (IL)-4/13/5 locus of ...
K, Murphy +3 more
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The Ribosome Binding Site Calculator
2011The Ribosome Binding Site (RBS) Calculator is a design method for predicting and controlling translation initiation and protein expression in bacteria. The method can predict the rate of translation initiation for every start codon in an mRNA transcript.
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Binding sites for calcium on tubulin
Biochemistry, 1977Calcium ions can inhibit the in vitro assembly of microtubules and, therefore, may play a role in the regulation of microtubule formation in vivo. In order to test the validity of this hypothesis; the interaction between calcium and pruified brain microtubular protein has been investigated by standard binding assays.
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3DLigandSite: Structure-Based Prediction of Protein–Ligand Binding Sites
Nucleic Acids Research, 2022Mark N. Wass +2 more
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Neurofibrosarcoma at Irradiation Site in a Patient With Neurofibromatosis and Wilms' Tumor
Ca-A Cancer Journal for Clinicians, 1981Jen-Yih Chu, Dennis M O'Connor
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Early Diagnosis of Oral Cancer: The Erythroplastic Lesion in High Risk Sites
Ca-A Cancer Journal for Clinicians, 1978Arthur Mashberg, A Mashberg, L Garfinkel
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