Results 201 to 210 of about 8,121,841 (424)

Receptor-Binding Sites on C3 and C3b [PDF]

, 1977
Manfred P. Dierich, Viktor A. Bokisch
openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Identical VL Region Sequences of Two Antibodies from Two Outbred Rabbits Exhibiting Complete Idiotypic Cross-Reactivity and Probably the Same Antigen-Binding Site Fine Structure [PDF]

, 1978
Daniel Ch. Brandt, Jean‐Claude Jaton
openalex   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen, Meng‐Meng Ji, Peng‐Peng Xu, Wei‐Li Zhao   +3 more
wiley   +1 more source

Nuclear magnetic resonance studies of the structure and binding sites of enzymes. IV. Cytidine 3'-monophosphate binding to ribonuclease.

, 1968
Donella H. Meadows, Oleg Jardetzky
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Properties of the Nicotinamide Adenine Dinucleotide-binding Sites of L-α-Glycerophosphate Dehydrogenase

, 1968
S J Kim, Brendan M. Anderson
openalex   +1 more source

Disease variants alter transcription factor levels and methylation of their binding sites

Nature Genetics, 2016
M. Bonder, R. Luijk, D. Zhernakova, M. Moed, Patrick Deelen, M. Vermaat, M. van Iterson, F. van Dijk, M. van Galen, J. Bot, R. Slieker, P. M. Jhamai, M. Verbiest, H. Suchiman, M. Verkerk, R. van der Breggen, J. V. van Rooij, N. Lakenberg, W. Arindrarto, S. Kiełbasa, I. Jonkers, Peter van ’t Hof, I. Nooren, M. Beekman, J. Deelen, D. van Heemst, A. Zhernakova, E. Tigchelaar, M. Swertz, A. Hofman, A. Uitterlinden, R. Pool, J. van Dongen, J. Hottenga, C. Stehouwer, C. V. D. van der Kallen, C. Schalkwijk, L. H. van den Berg, E. V. van Zwet, H. Mei, Yang Li, M. Lemire, T. Hudson, P. Slagboom, C. Wijmenga, J. Veldink, M. V. van Greevenbroek, C. V. van Duijn, D. Boomsma, A. Isaacs, R. Jansen, J. V. van Meurs, P. ’. ’t Hoen, L. Franke, B. Heijmans   +54 more
semanticscholar   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source