Results 201 to 210 of about 2,663,361 (333)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface. [PDF]

Nat Commun
Burendei B, Kaplan JP, Orellana GM, Liman ER, Forli S, Ward AB.   +5 more
europepmc   +1 more source

The binding of cyclic AMP receptor protein to two lactose promoter sites is not cooperative in vitro

, 1991
Janette M. Hudson, Michael G. Fried
openalex   +2 more sources

Dealing with stable structures at ribosome binding sites: Bacterial translation and ribosome standby [PDF]

, 2007
Cecilia Unoson, E. Gerhart H. Wagner
openalex   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

CFTR_TL: Transfer Learning-Enhanced Prediction of CFTR ATP Binding Sites with Multi-Window Convolutional Neural Networks. [PDF]

ACS Omega
Lee YC, Chang YY, Jhang WE, Le VT, Wei SS, Ou YY.   +5 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Mapping the sialic acid-binding sites of LuIII and H-1 parvovirus. [PDF]

J Virol
Busuttil K, Pittman N, Zachary J, Halder S, Geilen L, Singh A, Misseldine A, Kaplonek P, Chipman P, Heimburg-Molinaro J, Seeberger PH, Mietzsch M, Bennett AD, McKenna R.   +13 more
europepmc   +1 more source

A second guanyl nucleotide-binding site associated with adenylate cyclase. Distinct nucleotides activate adenylate cyclase and permit ADP-ribosylation by cholera toxin.

, 1983
D. Michael Gill, Roberta Meren
openalex   +1 more source

Localization of binding sites in protein structures by optimization of a composite scoring function [PDF]

, 2006
Andrea Rossi, Marc A. Martí‐Renom, Andrej Šali   +2 more
openalex   +1 more source