Results 271 to 280 of about 8,121,841 (424)

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Peptides developed against receptor binding sites of the E glycoprotein neutralize tick-borne encephalitis virus. [PDF]

Sci Rep
Petroušková P, Bhide K, Mochnáčová E, Kulkarni A, Jozefiaková J, Tkáčová Z, Maľarik T, Kucková K, Talpašová L, Víglaský J, Kevély Á, Koči K, Nováková E, Koči J, Bhide M.   +14 more
europepmc   +1 more source

Localization of the binding site for cell attachment in the alpha1(I) chain of collagen

, 1978
Hynda K. Kleinman, Ermona B. McGoodwin, George R. Martin, Robert J. Klebe, Peter P. Fietzek, David E. Woolley   +5 more
openalex   +1 more source

Fast Kinetic Studies on the Allosteric Interactions between Acetylcholine Receptor and Local Anesthetic Binding Sites [PDF]

, 1979
Thiérry Heidmann, Jean‐Pierre Changeux   +1 more
openalex   +1 more source

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

Nature, 1981
D. Wiley, I. Wilson, J. Skehel
semanticscholar   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Unraveling the Mechanism of Action, Binding Sites, and Therapeutic Advances of CFTR Modulators: A Narrative Review. [PDF]

Curr Issues Mol Biol
Baroni D.
europepmc   +1 more source

Cellular uptake and nuclear binding of insulin in human cultured lymphocytes: evidence for potential intracellular sites of insulin action.

, 1977
Ira D. Goldfine, George J. Smith, K. Y. Wong, A. L. Jones   +3 more
openalex   +1 more source

A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

Cell, 2006
Chia-Lin Wei, Qiang Wu, V. Vega, K. Chiu, Patrick W. P. Ng, Tao Zhang, Atif Shahab, H. Yong, Yutao Fu, Z. Weng, Jianjun Liu, Xiao Dong Zhao, Joon-Lin Chew, Y. Lee, V. Kuznetsov, W. Sung, L. Miller, B. Lim, E. Liu, Qiang Yu, H. Ng, Y. Ruan   +21 more
semanticscholar   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source