Results 21 to 30 of about 5,097,951 (211)
Galactoside-Binding Site in LacY [PDF]
Biochemistry, 2014 Although an X-ray crystal structure of lactose permease (LacY) has been presented with bound galactopyranoside, neither the sugar nor the residues ligating the sugar can be identified with precision at ~3.5 Å. Therefore, additional evidence is important for identifying side chains likely to be involved in binding.
Jiang, Xiaoxu +4 more
openaire +5 more sources
Surfaces, 2020 Surface density of adsorption sites on an adsorbent (including affinity-based sensors) is one of the basic input parameters in modeling of process kinetics in adsorption based devices.
Olga Jakšić +3 more
doaj +1 more source
Toxins, 2021 Cobra venoms contain three-finger toxins (TFT) including α-neurotoxins efficiently binding nicotinic acetylcholine receptors (nAChRs). As shown recently, several TFTs block GABAA receptors (GABAARs) with different efficacy, an important role of the TFTs ...
Lina Son +7 more
doaj +1 more source
Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2
Computational and Structural Biotechnology Journal, 2014 We have shown earlier that Kir2 channels are suppressed by the elevation of membrane cholesterol. Moreover, it is also well known that activation of Kir channels is critically dependent on a regulatory phospholipid, phosphatidylinositol-4,5-bisphosphate (
Avia Rosenhouse-Dantsker +2 more
doaj +1 more source
Variable structure motifs for transcription factor binding sites [PDF]
, 2010 Background: Classically, models of DNA-transcription factor binding sites (TFBSs) have been based on relatively few known instances and have treated them as sites of fixed length using position weight matrices (PWMs).
Evans, Kenneth J. +14 more
core +6 more sources
Models incorporating chromatin modification data identify functionally important p53 binding sites [PDF]
, 2013 Genome-wide prediction of transcription factor binding sites is notoriously difficult. We have developed and applied a logistic regression approach for prediction of binding sites for the p53 transcription factor that incorporates sequence information ...
Barker, Daniel +2 more
core +1 more source
Binding Sites of Bicarbonate in PEP Carboxylase [PDF]
, 2023 PhosphoEnolPyruvate Carboxylase is used in plant metabolism for fruit maturation or seed development, as well as in the C4 and CAM mechanisms in photosynthesis where it is used for the capture of hydrated CO2 (bicarbonate).
Nicolas, Chéron
core +2 more sources
Crystal engineering of porous coordination networks for C3 hydrocarbon separation
SmartMat, 2021 C3 hydrocarbons (HCs), especially propylene and propane, are high‐volume products of the chemical industry as they are utilized for the production of fuels, polymers, and chemical commodities.
Mei‐Yan Gao +3 more
doaj +1 more source
Mapping of the ligand-binding site on the b ' domain of human PDI: interaction with peptide ligands and the x-linker region [PDF]
, 2009 PDI (protein disulfide-isomerase) catalyses the formation of native disulfide bonds of secretory proteins in the endoplasmic reticulum. PDI consists of four thioredoxin-like domains, of which two contain redox-active catalytic sites (a and a'), and two ...
Freedman, R. B. +15 more
core +1 more source
Amyloid tracers detect multple binding sites in Alzheimer´s disease brain tissue. [PDF]
, 2013 Imaging fibrillar amyloid-β deposition in the human brain in vivo by positron emission tomography has improved our understanding of the time course of amyloid-β pathology in Alzheimer’s disease. The most widely used amyloid-β imaging tracer so far is 11C-
Nordberg, A, +9 more
core +1 more source