Results 31 to 40 of about 5,097,951 (211)

Being a binding site: Characterizing residue composition of binding sites on proteins [PDF]

Bioinformation, 2007
The Protein Data Bank contains the description of more than 45,000 three-dimensional protein and nucleic-acid structures today. Started to exist as the computer-readable depository of crystallographic data complementing printed articles, the proper interpretation of the content of the individual files in the PDB still frequently needs the detailed ...
Ivan, G, Szabadka, Z, Grolmusz, V
openaire   +3 more sources

The Chromosomal High-Affinity Binding Sites for the Drosophila Dosage Compensation Complex [PDF]

, 2008
Dosage compensation in male Drosophila relies on the X chromosome-specific recruitment of a chromatin-modifying machinery, the dosage compensation complex (DCC). The principles that assure selective targeting of the DCC are unknown.
Grimaud, Charlotte, Peter B Becker, Mitterweger Angelika, Grimaud Charlotte, Becker Peter B., Tobias Straub, Straub, Tobias, Mitterweger, Angelika, Peter B. Becker, Becker, Peter B., Gilfillan Gregor D., Gilfillan, Gregor D., Gregor D Gilfillan, Charlotte Grimaud, Angelika Mitterweger, Gregor D. Gilfillan, Straub Tobias   +16 more
core   +2 more sources

Quantitative analysis of uptake of free fatty acid by mammalian cells: lauric acid and human erythrocytes

Journal of Lipid Research, 1972
Quantitative aspects of the binding of free fatty acid to human erythrocytes were studied by measuring the distribution of various amounts of [1-14C]lauric acid between washed human erythrocytes and defatted human plasma albumin. Incubations were done at
Arthur A. Spector, J. Douglas Ashbrook, Elsa C. Santos, John E. Fletcher   +3 more
doaj   +1 more source

Nuclear factor I genomic binding associates with chromatin boundaries [PDF]

, 2013
BACKGROUND: The Nuclear Factor I (NFI) family of DNA binding proteins (also called CCAAT box transcription factors or CTF) is involved in both DNA replication and gene expression regulation.
Armelle Gaussin, Schmid, Christoph D., Mermod, Nicolas, Jozef Adamcik, Ambrosini, Giovanna, Schmid, C. D., Pjanic, P., Giovanna Ambrosini, Plasari, Genta, Genta Plasari, Bucher, P., Adamcik, Jozef, Kerschgens, J., Christoph D Schmid, Petar Pjanic, Pjanic, Petar, Kerschgens, Jan, Ambrosini, G., Pjanic, Milos, Gaussin, Armelle, Gaussin, A., Pjanic, M., Philipp Bucher, Plasari, G., Jan Kerschgens, Adamcik, J., Giovani Dietler, Bucher, Philipp, Milos Pjanic, Dietler, Giovani, Dietler, G., Schmid, C.D., Nicolas Mermod, Mermod, N., Ambrosini G, Adamcik J, Plasari G, Dietler G, Pjanic P, Gaussin A, Bucher P, Schmid CD, Kerschgens J, Pjanic M, Mermod N   +44 more
core   +2 more sources

Diversity of molecular targets and signaling pathways for CBD

Pharmacology Research & Perspectives, 2020
Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that examined the behavioral effects of CBD concluded that it lacks the psychotomimetic ...
Douglas L. deAlmeida, Lakshmi A. Devi
doaj   +1 more source

Identification of hACE2-interacting sites in SARS-CoV-2 spike receptor binding domain for antiviral drugs screening

Virus Research, 2022
The key structure of the interface between the spike protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and human angiotensin-converting enzyme 2 (hACE2) acts as an essential switch for cell entry by the virus and drugs targets ...
Xiaopeng Hu, Jiahua Cui, Jun Chen, Shujuan Du, Xinyu Wang, Yabin Zhang, Jiajun Qian, Haifeng Chen, Fang Wei, Qiliang Cai, Jinping Jia, Ji Wu   +11 more
doaj   +1 more source

Prediction of Functional Sites in SCOP Domains using Dynamics Perturbation Analysis [PDF]

, 2008
Dynamics perturbation analysis (DPA) finds regions in a protein structure where proteins are "ticklish", i.e., where interactions cause a large change in protein dynamics.
Michael E. Wall, Dengming Ming, Judith D. Cohn, Michael Wall, Judith Cohn   +4 more
core   +1 more source

Automatic generation of 3D motifs for classification of protein binding sites [PDF]

, 2007
BACKGROUND: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of protein function. Protein 3D structures can be clustered according to their fold
Herzyk, P, Herzyk, Pawel, Gilbert, D, Nebel, J, Gilbert, David R., Jean-Christophe Nebel, Herzyk, P., Gilbert, D.R., Nebel Jean-Christophe, Nebel, J.C., David R Gilbert, Gilbert David R, Nebel, Jean-Christophe, Pawel Herzyk, Herzyk Pawel   +14 more
core   +1 more source

A novel prediction method for protein DNA-binding residues based on neighboring residue correlations

Biotechnology & Biotechnological Equipment, 2022
Accurately identifying the protein DNA-binding residues is important for understanding the protein–DNA recognition mechanism and protein function annotation.
Jiazhi Song, Guixia Liu, Jingqing Jiang
doaj   +1 more source

Amyloid and Tau Positron Emission Tomography Imaging in Alzheimer’s Disease and Other Tauopathies

Frontiers in Aging Neuroscience, 2022
The detection and staging of Alzheimer’s disease (AD) using non-invasive imaging biomarkers is of substantial clinical importance. Positron emission tomography (PET) provides readouts to uncover molecular alterations in the brains of AD patients with ...
Cinzia Maschio, Ruiqing Ni, Ruiqing Ni
doaj   +1 more source